Binding of Isaac: Rebirth Wiki

Added in Repentance
Disambig-dark.png This article is about Eye Drops, similar in appearance to Tropicamide.

Eye Drops is a passive item added in The Binding of Isaac: Repentance.


  • Decreases the tear delay of tears fired from Isaac's left eye by ~28%.
    • The difference in fire rates causes Isaac's tears to be fired at a staggered rate.
    • The first shot in a while is always a double shot.


  • Every type of attack that does not use both of Isaac's eyes benefits from the fire rate up, but will not have staggered attack rate. These include, for example:
  • Multi-shot attacks such as 20/20 20/20 and Mutant Spider Mutant Spider do have staggered firing.
  • The effectiveness of this item increases with Isaac’s tears stat, but not with items that directly decrease tear delay.