Eve's Mascara is an unlockable passive item.
Effects
- 2x damage multiplier.
- -0.5 shot speed.
0.5x tears / 2x tear delay multiplier. (The player's tear value will always be halved.)- 0.66x tears / 1.5x tear delay multiplier.
0.5x tears / 2x Notes
- Eve's Mascara is DPS neutral, though often the reduction of shot speed is a downgrade.
- Combos very well with any item that scales with damage but not with fire rate, such as Rotten Baby or Fate's Reward.
- Eve's Mascara is effectively a 33% increase in DPS, and the shot speed down is no longer as detrimental due to changes in how range works.
Synergies
- Abyss: When Eve's Mascara is picked up instead of being converted into a locust, it grants all of Abyss's locusts the high damage up without suffering the tears down allowing Isaac to increase his damage rate substantially the more items he uses Abyss on.
- Epic Fetus: Missiles are not affected by low shot speed and the fire rate difference is negligible, granting double damage with nearly no downside.
- Mom's Knife: The Knife is not affected by shot speed. Tears down and 2x damage multiplier still apply.
- Trisagion: Beams turn black and do double damage. The low shot speed makes beams damage enemies more frequently.
- Tech X: Tech X benefits from a lower shot speed due to it staying on enemies longer and is also not affected by range, giving little downsides.
- The tears down can be a major downside as it takes longer to charge Tech X and the damage dealt by Tech X is less than Isaac's damage when it is not fully charged.
Interactions
- Dr. Fetus / Ipecac: Shots travel a very short distance, so having Host Hat or Pyromaniac is strongly recommended.
- Eve's Mascara: No further effect when stacked.
- The Ludovico Technique: Not recommended. Tear travels very slowly, making it hard to kill mobile enemies.
In-game Footage
 Eve Unlocks
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 Boss Rush Unlocks
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 The Binding of Isaac: Rebirth
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