Epiphora is a passive item added in The Binding of Isaac: Afterbirth.
Effects[ | ]
Tear delay gradually decreases as the player shoots in one direction. Accuracy also decreases as the fire rate increases.
- At max "charge", it will reduce tear delay by half, rounding down.
- Fire rate gradually increases as the player shoots in one direction. Accuracy also decreases as the fire rate increases.
- At max "charge", it will increase fire rate by double.
- Rate of fire returns to its original value if Isaac stops firing, changes firing directions, uses an active item, or is hit.
- Being hit, changing rooms, and using items no longer reset the Epiphora bonus.
- Entering an unexplored boss room will reset the Epiphora bonus.
- During the delay when transitioning between rooms, picking up an item, or using an active item, it's possible to change the firing direction without resetting the bonus.
Being hit, changing rooms, and using items no longer reset the Epiphora bonus.Notes[ | ]
- Epiphora technically works with items that require a charge (such as Monstro's Lung), but requires releasing the key or button, causing players to lose the effect.
Synergies[ | ]
- Analog Stick: Epiphora's bonus will not reset when switching fire diagonally, as long as Isaac's head doesn't turn.
- Continuum: Reduces the need to change firing direction, allowing Isaac to maintain the increased rate of fire.
- Dr. Fetus / Ipecac: Firing bombs continually will decrease tear delay, although doing so is not recommended since it increases the risk of self-damage.
- The Forgotten: When tapping the attack button in a single direction repeatedly, the Ephiphora effect will cause the bone swings to speed up.
- How to Jump: Changing firing direction while jumping does not reset the bonus, similar to when changing rooms.
- Incubus: Incubus's fire rate will match Isaac's.
- The Ludovico Technique: Fire rate increases while moving the tear in one direction; it has a negligible effect during normal gameplay.
- Marked: Both items work as normal, with tear rate gradually increasing until Isaac turns his head, which can happen via him or the crosshair moving too out of parallel.
- Rubber Cement: Reduces the need to change firing direction allowing Isaac to maintain the increased rate of fire.
- Rock Bottom: Isaac will never lose the benefits of Epiphora, even after he stops firing. This effectively makes Epiphora a substantial tears up. Fully charging Ephiphora is still needed to gain a higher tears stat if an item that would increase the tears stat is picked up.
- Tractor Beam: Fire rate still increases when shooting in one direction, but will stay on the line (i.e. no loss in accuracy).
- Loki's Horns / Mom's Eye: Allows for firing in multiple directions at once, decreasing need to change firing direction.
Interactions[ | ]
- Charging items such as Brimstone, Chocolate Milk, Cursed Eye, Mom's Knife, Monstro's Lung, and Tech X: Effect only activates when holding charge in a specific direction, and deactivates when the charge is released, effectively making Epiphora useless unless Isaac has exceedingly low fire rate.
- Soy Milk / Almond Milk + Chocolate Milk / Cursed Eye / Monstro's Lung / Tech X: Due to constant firing, Epiphora's fire rate bonus can now be used.
- Soy Milk / Almond Milk + Brimstone: The Brimstone laser only gains the increased damage from higher tear rates when the laser starts firing, making Epiphora's bonus useless.
- Epic Fetus: Overrides Epiphora.
- Lilith: Lilith and her Incubus cannot gain extra fire rate from Epiphora.
- Incubus' fire rate will increase without the accuracy penalty
- Tainted Isaac: If you pick up an item and drop Epiphora while holding the attack button you will keep the fire rate. The effect will disappear upon entering a new floor.
- Bag of Crafting: Bag of Crafting can be used to switch directions without reducing fire rate when activated.
In-game Footage[ | ]
Trivia[ | ]
- Epiphora is an overflow of tears onto the face.
 The Binding of Isaac: Rebirth
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