Binding of Isaac: Rebirth Wiki

(except in Rebirth)

Epiphora is a passive item added in The Binding of Isaac: Afterbirth.

Effects[ | ]

  • (except in Repentance) Tear delay gradually decreases as the player shoots in one direction. Accuracy also decreases as the fire rate increases.
    • At max "charge", it will reduce tear delay by half, rounding down.
  • (in Repentance) Fire rate gradually increases as the player shoots in one direction. Accuracy also decreases as the fire rate increases.
    • At max "charge", it will increase fire rate by double.
  • Rate of fire returns to its original value if Isaac stops firing, changes firing directions, uses an active item, or is hit.
    • (in Afterbirth † and Repentance) Being hit, changing rooms, and using items no longer reset the Epiphora bonus.
    • (in Repentance) Entering an unexplored boss room will reset the Epiphora bonus.
      • During the delay when transitioning between rooms, picking up an item, or using an active item, it's possible to change the firing direction without resetting the bonus.

Notes[ | ]

  • Epiphora technically works with items that require a charge (such as Collectible Monstro's Lung iconMonstro's Lung), but requires releasing the key or button, causing players to lose the effect.

Synergies[ | ]

  • (in Afterbirth † and Repentance)Collectible Analog Stick iconAnalog Stick: Epiphora's bonus will not reset when switching fire diagonally, as long as Isaac's head doesn't turn.
  • Collectible Continuum iconContinuum: Reduces the need to change firing direction, allowing Isaac to maintain the increased rate of fire.
  • Collectible Dr. Fetus iconDr. Fetus / Collectible Ipecac iconIpecac: Firing bombs continually will decrease tear delay, although doing so is not recommended since it increases the risk of self-damage.
  • Character The Forgotten iconThe Forgotten: When tapping the attack button in a single direction repeatedly, the Ephiphora effect will cause the bone swings to speed up.
  • Collectible How to Jump iconHow to Jump: Changing firing direction while jumping does not reset the bonus, similar to when changing rooms.
  • Collectible Incubus iconIncubus: Incubus's fire rate will match Isaac's.
  • Collectible The Ludovico Technique iconThe Ludovico Technique: Fire rate increases while moving the tear in one direction; it has a negligible effect during normal gameplay.
  • Collectible Marked iconMarked: Both items work as normal, with tear rate gradually increasing until Isaac turns his head, which can happen via him or the crosshair moving too out of parallel.
  • Collectible Rubber Cement iconRubber Cement: Reduces the need to change firing direction allowing Isaac to maintain the increased rate of fire.
  • (in Repentance)Collectible Rock Bottom iconRock Bottom: Isaac will never lose the benefits of Epiphora, even after he stops firing. This effectively makes Epiphora a substantial tears up. Fully charging Ephiphora is still needed to gain a higher tears stat if an item that would increase the tears stat is picked up.
  • Collectible Tractor Beam iconTractor Beam: Fire rate still increases when shooting in one direction, but will stay on the line (i.e. no loss in accuracy).
  • Collectible Loki's Horns iconLoki's Horns / Collectible Mom's Eye iconMom's Eye: Allows for firing in multiple directions at once, decreasing need to change firing direction.

Interactions[ | ]

  • Charging items such as Collectible Brimstone iconBrimstone, Collectible Chocolate Milk iconChocolate Milk, Collectible Cursed Eye iconCursed Eye, Collectible Mom's Knife iconMom's Knife, Collectible Monstro's Lung iconMonstro's Lung, and Collectible Tech X iconTech X: Effect only activates when holding charge in a specific direction, and deactivates when the charge is released, effectively making Epiphora useless unless Isaac has exceedingly low fire rate.
  • Collectible Epic Fetus iconEpic Fetus: Overrides Epiphora.
  • Character Lilith iconLilith: Lilith and her Incubus cannot gain extra fire rate from Epiphora.
    • (in Repentance) Incubus' fire rate will increase without the accuracy penalty
  • Character Tainted Isaac iconTainted Isaac: If you pick up an item and drop Epiphora while holding the attack button you will keep the fire rate. The effect will disappear upon entering a new floor.
  • (in Repentance)Collectible Bag of Crafting iconBag of Crafting: Bag of Crafting can be used to switch directions without reducing fire rate when activated.

In-game Footage[ | ]

Trivia[ | ]

  • Epiphora is an overflow of tears onto the face.