Epic Fetus

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Epic   Fetus
Removed in RepentanceItem icon
Added in RepentanceItem icon
Item altar
"On-demand air strike"
Table dividing line 1.png
Item ID
5.100.168
Character Appearance
Character appearance
Tear Appearance
Tear appearance
Table dividing line 2.png
Table dividing line 3.png
Collection Grid
Removed in Afterbirth(page 2, column 5, row 7)
Added in Afterbirth(page 2, column 5, row 3)
Unlock Method
Epic Fetus Complete The Family Man (challenge #19)

Epic Fetus is a special unlockable passive item.

Effects[edit | edit source]

  • Isaac's tears are replaced with guided missiles.
    • Missiles deal 20 times Isaac's damage.

Notes[edit | edit source]

  • Removed in Repentance Epic Fetus overrides most items in the game and has the highest priority of all tear modifiers, over 15►Brimstone Brimstone and 15►Mom's Knife Mom's Knife.
  • Isaac's tear delay determines how quickly a new (set of) missile(s) can be fired after the previous one has landed. Barring very high tear delay, this has little effect on damage rate due to the delay of the missiles themselves.
  • Missiles benefit from some bomb modifier items, though at a lesser scale compared to 15►Dr. Fetus Dr. Fetus.

Synergies[edit | edit source]

  • Added in Afterbirth 15►20/20 20/20/Added in Afterbirth † Bookworm/Conjoined/15►Mutant Spider Mutant Spider/15►The Inner Eye The Inner Eye: Fires a barrage of missiles.
  • 15►Blood Clot Blood Clot / 15►Chemical Peel Chemical Peel: Each missile has a 50% chance to deal 20 or 40 points more damage, respectively.
  • 15►Bob's Curse Bob's Curse/15►Scorpio Scorpio: Missiles gain a poison effect.
  • Added in Afterbirth 15►Brimstone Brimstone: Missile explosions shoot ten blood lasers in all directions.
  • 15►Butt Bombs Butt Bombs: Missile explosions will cloud up the screen, briefly confusing and dealing 10 damage to all enemies in the room.
  • 15►Fire Mind Fire Mind/Added in Afterbirth 15►Hot Bombs Hot Bombs: Missile explosions leave behind a fire that damage enemies on contact. Fire Mind's burn effect is overriden.
  • Added in Afterbirth † The Forgotten: The charge attack is replaced by a missile in the Forgotten's hand and a crosshair that may be moved for an indefinite amount of time. The missile is thrown at the crosshair when all attack buttons are released, with an additional melee swing in the same direction. The melee attack is unaffected.
  • Added in Afterbirth15►Glitter Bombs Glitter Bombs: Missile explosions have a small chance of spawning pickups.
  • Added in Afterbirth Homing tears: The crosshair slowly slides towards enemies.
  • Added in Afterbirth15►Host Hat Host Hat/15►Pyromaniac Pyromaniac: Isaac becomes immune to his own airstrikes.
  • 15►Ipecac Ipecac: Missiles have a poison effect, have a larger blast radius and deal drastically increased damage, as the +40 damage from Ipecac is run through the damage multiplier of Epic Fetus.
  • Added in Afterbirth 15►Mom's Knife Mom's Knife: Missile explosions shoot a ring of ten knives.
  • Added in Afterbirth 15►Monstro's Lung Monstro's Lung: 2 to 4 additional crosshairs orbit the main crosshair, and missiles are fired onto each crosshair.
  • 15►Mysterious Liquid Mysterious Liquid: Every missile explosion leaves a small, lasting pool of creep.
    • Added in Afterbirth: The pool of creep left by the explosion is larger.
  • 15►Polyphemus Polyphemus: Increased tear delay, but massively increases the missiles' blast radius and damage, as Polyphemus' damage multiplier is run through the damage multiplier of Epic Fetus.
  • 15►Sad Bombs Sad Bombs: Missile explosions fire ten tears in all directions. The shrapnel's damage is not run through the damage multiplier of Epic Fetus.
  • Added in Afterbirth 15►Strange Attractor Strange Attractor: Enemies get drawn towards the crosshair.
  • Added in Afterbirth 15►Technology Technology: Both fire normally. Missile explosions shoot ten Technology beams in all directions.
  • Added in Afterbirth15►Tech X Tech X: Missile explosions shoot ten Technology beams in all directions.

Interactions[edit | edit source]

  • Added in Afterbirth15►8 Inch Nails 8 Inch Nails: Missile explosions retain the knockback boost, so enemies that survive the blast will be knocked back far.
  • 15►Anti-Gravity Anti-Gravity: Overridden by Epic Fetus. Stat effects are still applied.
  • Azazel: Overridden by Epic Fetus.
  • 15►Bobby-Bomb Bobby-Bomb/Added in Afterbirth15►Bomber Boy Bomber Boy/15►Mr. Mega Mr. Mega/Added in Afterbirth15►Scatter Bombs Scatter Bombs/Added in Afterbirth15►Sticky Bombs Sticky Bombs/Added in Repentance15►Ghost Bombs Ghost Bombs: No effect.
  • Removed in Afterbirth15►Brimstone Brimstone: Overidden by Epic Fetus.
  • 15►Chocolate Milk Chocolate Milk: Reduces Isaac's tear delay by 20%. Missiles can't be charged.
  • 15►Cursed Eye Cursed Eye: Overridden by Epic Fetus.
  • 15►Dr. Fetus Dr. Fetus: Overridden by Epic Fetus.
  • 15►Godhead Godhead: Overriden by Epic Fetus.
    • Added in Afterbirth Stat effects apply and the crosshair gains a homing effect, but missiles do not have a damaging aura.
  • Removed in Afterbirth Homing tears: Overridden by Epic Fetus.
  • Added in Afterbirth15►Incubus Incubus: Incubus fires normal tears while the crosshair is being aimed.
  • 15►The Ludovico Technique The Ludovico Technique: Overridden by Epic Fetus.
  • Removed in Afterbirth 15►Monstro's Lung Monstro's Lung: Overridden by Epic Fetus.
  • Removed in Afterbirth 15►Mom's Knife Mom's Knife: Overridden by Epic Fetus.
  • 15►The Parasite The Parasite: No effect.
  • 15►Tammy's Head Tammy's Head / Added in Afterbirth †15►Varicose Veins Varicose Veins: Fires only normal tears, not missiles.
  • 15►Soy Milk Soy Milk: Not recommended. Damage of missiles is drastically reduced, and unlike normal tears, the fire rate will not significantly increase.
  • Added in Repentance15►Spirit Sword Spirit Sword: Overrides Epic Fetus.
  • Removed in Afterbirth 15►Technology Technology: Overriden by Epic Fetus.
  • 15►Technology 2 Technology 2: Not recommended. Technology 2 is overriden by Epic Fetus, but the damage multiplier is still applied, massively reducing the missiles' damage.
  • 15►Tiny Planet Tiny Planet: Overridden by Epic Fetus.
  • Added in Afterbirth15►The Wiz The Wiz: Makes two missiles drop in quick succession, and control of the crosshair is rotated 45 degrees clockwise. Not recommended, as it makes controlling the crosshair harder.

In-game Footage[edit | edit source]

Trivia[edit | edit source]

  • In the original game it was possible to control the crosshair with the mouse. This was removed in Rebirth.
    • Mouse control can however be re-enabled by editing the options.ini file in C:\Users\<username>\Documents\My Games\Binding of Isaac Afterbirth/Rebirth and changing the line MouseControl=0 into MouseControl=1. Also useful for The Ludovico Technique.
  • The Dr. Fetus and Epic Fetus items are based off of Dr. Fetus, the main villain in Super Meat Boy which is a game by Edmund McMillen (the creator of The Binding of Isaac: Rebirth).
  • This item is used in Glass Cannon (challenge #11).

Seeds[edit | edit source]

PC GOBD W8TB (Treasure Room adjacent to spawn)

PS4 8ETR M2M9 (First floor Treasure Room)

Vita 8G4J JFH8 (Treasure Room adjacent to spawn)


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