Binding of Isaac: Rebirth Wiki
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(in Repentance)

Empty Heart is an unlockable passive item added in The Binding of Isaac: Repentance.

Effects[ | ]

  • If Isaac has one red heart or less at the beginning of a floor, an empty heart container is added.

Notes[ | ]

Synergies[ | ]

  • Collectible Adrenaline iconAdrenaline: Activates the damage up effect of Adrenaline if conditions are met to grant an empty heart container at the beginning of each floor.
  • Crow HeartCrow Heart: If no Devil BeggarDevil Beggars or Blood Donation MachineBlood Donation Machines can be found, the Crow Heart trinket is a great way to guarantee red hearts are lost so long as you still have non-red health available.
  • Collectible Dark Prince's Crown iconDark Prince's Crown: The heart containers are empty when granted, which allows the crown's buff to stay active when advancing floors.
  • Collectible Guppy's Paw iconGuppy's Paw: The heart containers granted by Empty Heart can be used by Guppy's Paw while staying at or below 1 red heart, granting massively increased survivability.
  • Character Lazarus iconLazarus: The heart containers granted by Empty Heart allows Lazarus to effectively negate the downside that removes a single heart container on death, allowing him to purposefully use his mechanic to get a +0.5 damage up per floor. (As long as he still proceeds at one red heart or less)
  • Collectible Potato Peeler iconPotato Peeler: The heart containers granted by Empty Heart can be used by Potato Peeler while staying at or below 1 red heart, granting increased damage and a Collectible Cube of Meat iconCube of Meat per floor.

In-game footage[ | ]

Bugs[ | ]

Bug Bug! If Isaac is operating only on soul hearts and manages to get 12 empty heart containers by using this item, he will die immediately upon leaving the spawn room or picking up an item.
Bug Bug! Using Glowing Hourglass to go back to the previous floor will keep the new empty hearts that was obtained from Empty Heart.


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