Binding of Isaac: Rebirth Wiki
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Embryos are monsters that hop around the room, dealing contact damage. They are relatively harmless as they do not move much from their position and don’t target the player.

Trivia[ | ]

  • (in Rebirth) Embryos count as the Boss Blastocyst ingameBlastocyst boss. Blastocyst still splits into Embryos.
  • Embryos bear a strong resemblance to Spewer: the star of the game Spewer which was also created by Edmund Mcmillen, the maker of The Binding of Isaac.
  • In the original The Binding of Isaac, they have health bars (like mini-bosses or bosses have).
  • Embryos can often be seen in rooms with Blood Donation MachineBlood Donation Machines.
  • In the Bestiary, Embryos have a unique appearance in which they're smiling.


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