E Coli

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E   Coli
Item icon
Item altar
"Turdy touch"
Table dividing line 1.png
Item ID
Character Appearance
Character appearance
Table dividing line 2.png
Table dividing line 3.png
Collection Grid
Removed in Afterbirth(page 3, column 2, row 4)
Added in Afterbirth(page 2, column 12, row 6)

E Coli is a passive item.

Effects[edit | edit source]

  • Enemies that touch Isaac are turned into Poop.
  • Added in Afterbirth This item belongs to the Oh Crap set. Collecting three items from this set will transform Isaac into a walking pile of poop.

Notes[edit | edit source]

  • Bosses cannot be turned into poop.
  • Poop created by this item is not grid-aligned, and flashes red when hit, similar to damaging monsters.
    • Added in Afterbirth † Poops produced by E Coli crumble upon being attacked, identically to regular poops.
  • If you touch the middle section of a Grub with E Coli, it will then split and become two heads (rather than destroying and spawning Maggots).
  • Mullibooms can be turned into poop without taking damage.
  • The poops vanish if the room is left and then returned to.
  • Added in Afterbirth / Removed in Repentance Poops created by E Coli do not heal Isaac when he has the Oh Crap transformation.
    • Added in Repentance Poops created by E Coli heal Isaac when he has the Oh Crap transformation.

Synergies[edit | edit source]

Interactions[edit | edit source]

In-game Footage[edit | edit source]

Trivia[edit | edit source]

  • Escherichia coli is a type of intestinal bacteria present naturally in the human intestinal system. However, some harmful strains of E. Coli can cause food poisoning.
  • This item is used in High Brow (challenge #2).

Seeds[edit | edit source]

PC DXGN OP4D (Treasure Room adjacent to spawn)

PS4 F1WD FBBN (Treasure Room adjacent to spawn)

Switch Greed mode only 8YRM FTHE (First Golden Treasure Room)

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