E. Coli

Item Icon
Pickup Quote	"Turdy touch"
Entity ID	5.100.236
Character Appearance
Item Pool	None
Quality	1
Item Tags
Collection Grid	(page 3, column 2, row 4) (page 2, column 12, row 6)

E. Coli is a passive item.

Effects

• Enemies that touch Isaac are transformed into poop.
• This item belongs to the Oh Crap set. Collecting three items from this set will transform Isaac into a walking pile of poop.

Notes

• Bosses cannot be turned into poop.
• Poop created by this item is not grid-aligned, and flashes red when hit, similar to damaging monsters.
  • Poops produced by E. Coli crumble upon being attacked, identically to regular poops.
• If you touch the middle section of a Grub with E. Coli, it will then split and become two heads (rather than destroying and spawning Maggots).
• Mullibooms can be turned into poop without taking damage.
• The poops vanish if the room is left and then returned to.
• Poops created by E. Coli do not heal Isaac when he has the Oh Crap transformation.
• Poops created by E. Coli heal Isaac when he has the Oh Crap transformation.

Synergies

• Isaac's Heart: Isaac can turn enemies into poop without taking damage.
• Midas' Touch: Enemies touched are turned into Golden Poop.
• Unicorn Stump: Provides invincibility during which enemies can be touched.
• Lodestone: If an enemy is hit by a lodestone tear perfectly simultaneously with it being turned into poop, the resulting poop will be tinted black and have a lodestone aura that sucks in enemies. This poop will return to normal after a few seconds.
• Both Midas' Touch and E. Coli affect Tainted Forgotten's body, causing enemies that touch the body to freeze and turn into poop respectively.

Interactions

• Brown Cap: The generated poops are affected and will explode when destroyed.
• Hallowed Ground: The generated poops cannot be white.
• Meconium: The generated poops cannot be black.
• Serpent's Kiss / The Virus: The poops won't drop Black Hearts, negating the touch effect from these items on non-bosses.

Trivia

• Escherichia coli is a type of intestinal bacteria present naturally in the human intestinal system. However, some harmful strains of E. Coli can cause food poisoning.
• This item is used in High Brow (challenge #2) and Scat Man (challenge #36).

Seeds

PC DXGN OP4D (Treasure Room adjacent to spawn)

PS4 F1WD FBBN (Treasure Room adjacent to spawn)

Switch 8YRM FTHE (First Golden Treasure Room)

The Binding of Isaac: Rebirth
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