Dice may refer to the following:
Collectibles[]
D1, an activated collectible that duplicates 1 random pickup, trinket, or chest in the current room.
D4, an activated collectible that re-rolls each of Isaac's items into a random item from the 
Treasure Room item pool. from the pool where the item it replaces was acquired.- The D6, an activated collectible that replaces every pedestal item in the current room (not pickups or trinkets) with other random items corresponding to the current room's item pool.
- Eternal D6, an activated collectible that has the same effect as the D6, but with a much shorter recharge and a chance to make the items disappear instead.
- D7, an activated collectible that restarts the room and respawns all monsters.
- D8, an activated collectible that re-rolls Isaac's speed, range, tears, and damage.
- D10, an activated collectible that turns all of the monsters in a room into different ones.
- D12, an activated collectible that re-rolls all rocks in the current room into other obstacles.
- D20, an activated collectible that randomizes all pickups and chests within a room.
- D100, an activated collectible that combines the effects of multiple dice items.
- D infinity, an activated collectible that acts like a random die. acts like any selected die item.
- Spindown Dice, an activated collectible that transforms items in the current room into items with 1 lower internal ID number, skipping items that haven't been unlocked or are invalid.
Trinkets[]
- Cracked Dice, a trinket that, when Isaac takes damage, gives a chance that eitherThe D6, D8, D12, or D20 effect will activate.
- Dice Bag, a trinket that gives Isaac a chance to spawn a die consumable for the duration of each new room.
Other[]
- Dice Shard, a consumable item that acts like The D6 and the D20 combined.
- Dice Rooms, a room found behind a double-key door that randomizes some aspect of the game.
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 The Binding of Isaac: Rebirth
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