Devil Room (Item Pool)

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The Devil Room pool is the pool of items that can be found in the Devil Room. All items can be bought for some number of Red Heart containers. If Isaac has no Red Heart containers, items can be bought for three Soul Hearts / Black Hearts.

Activated Collectibles[edit | edit source]

Name ID Icon Weight Description
Full red heart 1 Heart Cost
The Book of Belial 5.100.34
The Book of Belial
3 rooms
1 +2 damage for the current room.
Removed in Afterbirth Guarantees a Devil Room or Angel Room will be open after beating a boss while holding it. Added in Afterbirth Increases the chance by 12.5%.
The Book of Sin 5.100.97
The Book of Sin
4 rooms
1 Spawns a random pickup, pill, card, or trinket.
Guppy's Head 5.100.145
Guppy's Head
1 rooms
1 Spawns 2-4 friendly Blue Flies that damage enemies.
Guppy's Paw 5.100.133
Guppy's Paw
1 Upon use, converts one Heart Container into three Soul Hearts.
The Necronomicon 5.100.35
The Necronomicon
6 rooms
1 Deals 40 damage to every enemy in the room.
Razor Blade 5.100.126
Razor Blade
1 On use, takes one heart of health and grants +1.2 damage for the current room.
We Need to Go Deeper! 5.100.84
We Need to Go Deeper!
6 rooms
1 Creates a trapdoor to go to the next floor. If used in The Womb The Womb, it will create a trapdoor to Sheol Sheol, even if the player hasn't unlocked it.
Added in Afterbirth Mega Blast 5.100.441
Mega Blast
12 rooms
1 Upon use, Isaac fires a laser similar to the one used by Mega Satan. This laser deals massive damage, lasts for approximately 15 seconds, and persists between rooms. Isaac is pushed backwards by the force of the laser while it is active.
Added in Afterbirth † Book of the Dead 5.100.545
Book of the Dead
4 rooms
1 Upon use, spawns a friendly Bony or an orbital bone for each enemy killed in the current room.
Added in Afterbirth † Plan C 5.100.475
Plan C
One time use
1 Kills all enemies in the room, then kills Isaac three seconds later.
Added in Afterbirth † Void 5.100.477
6 rooms
1 Consumes all pedestal items in the room. Active items will have their effects added to Void, and passive items will grant stat upgrades.
Added in Repentance Dark Arts 5.100.705
Dark Arts
6 seconds
1 Makes Isaac invulnerable and intangible for one second. When the effect ends, all enemies Isaac ran through take damage and Isaac temporarily gains +1 damage for each one.
Added in Repentance Forget Me Now 5.100.127
Forget Me Now
One time use
1 On use, re-generates the current floor with a new layout. Isaac loses Forget Me Now, but keeps other items and consumables picked up on the original floor.
Added in Repentance Sulfur 5.100.556
3 rooms
1 Grants 15►Brimstone Brimstone for the current room.
Full red heartFull red heart 2 Hearts Cost
Satanic Bible 5.100.292
Satanic Bible
6 rooms
1 Gives one Black Heart. Added in Repentance Replaces the boss room item on the current floor with a Devil deal.
The Nail 5.100.83
The Nail
6 rooms
1 Gives Removed in Repentance one Soul Heart Added in Repentance half a Black Heart. For the current room; +0.7 damage, -0.18 speed, allows Isaac to break rocks and damage enemies by walking over them.
Added in Afterbirth † Sacrificial Altar 5.100.536
Sacrificial Altar
One time use
1 Sacrifices up to 2 familiars and spawns an item from the Devil Room pool for each familiar sacrificed. Converts all friendly spiders and flies into coins.

Passive Collectibles[edit | edit source]

Name ID Icon Weight Description
Full red heart 1 Heart Cost
Brother Bobby 5.100.8 Brother Bobby 1 A familiar that follows Isaac around shooting normal tears.
Ceremonial Robes 5.100.216 Ceremonial Robes 1 Grants 3 Black Hearts, and +1 damage.
Contract From Below 5.100.241 Contract From Below 1 Doubles the number of most room clear awards, but reduces the overall chance of getting one by 1/3.
Dark Bum 5.100.278 Dark Bum 1 Spawns a familiar that follows Isaac around and collects Red Hearts for himself. For every 1½ Red Hearts collected, Dark Bum will give a Soul Heart, a hostile Spider, a friendly Blue Spider, Added in Repentance or a random card, rune or pill.
Dark Matter 5.100.259 Dark Matter 1 +1 damage, adds a chance to shoot fear tears.
Demon Baby 5.100.113 Demon Baby 1 Spawns a familiar that follows Isaac and automatically fires at enemies in its reach.
Ghost Baby 5.100.163 Ghost Baby 1 Spawns a familiar that follows Isaac around and fires spectral tears.
Gimpy 5.100.225 Gimpy 1 Gives chance of spawning a Soul Heart when taking damage. Enemies have a chance to drop a Half Red Heart after being killed.
Goat Head 5.100.215 Goat Head 1 A Devil Room / Angel Room Door will always spawn after every boss fight, excluding the first floor and floors after Utero II/Womb II.
Guppy's Collar 5.100.212 Guppy's Collar 1 Grants a permanent 50% chance to respawn with 1/2 of a Red Heart after death.
Guppy's Hair Ball 5.100.187 Guppy's Hair Ball 1 Spawns a familiar that loosely follows behind Isaac, which blocks shots can be swung like a flail to damage enemies. Grows bigger by killing enemies.
Guppy's Tail 5.100.134 Guppy's Tail 1 Room clear awards have a 1/3 chance of being replaced with a chest and a 1/3 chance being replaced with nothing.
Headless Baby 5.100.269 Headless Baby 1 Spawns a familiar that follows Isaac, leaving blood creep on the ground.
Missing Page 2 5.100.262 Missing Page 2 1 Grants one Black Heart. Upon taking damage that reduces Isaac's health to one heart or less, activates 15►The Necronomicon The Necronomicon effect, dealing 40 damage to all enemies in the room.
Ouija Board 5.100.115 Ouija Board 1 Grants spectral tears that travel through obstacles (but not enemies) instead of breaking on impact with them.
Pentagram 5.100.51 Pentagram 1 +1 damage, increases Devil Room / Angel Room chance by 10%.
Rotten Baby 5.100.268 Rotten Baby 1 Spawns a familiar that spawns a Blue Fly when Isaac shoots. It can only have one Fly at a time.
Sacrificial Dagger 5.100.172 Sacrificial Dagger 1 Spawns a dagger orbital familiar, dealing 225 damage per second and blocking enemy shots.
Sister Maggy 5.100.67 Sister Maggy 1 Spawns a familiar that follows Isaac around shooting normal tears.
The Mark 5.100.79 The Mark 1 Grants one Soul Heart, +1 damage, and +0.2 speed.
Whore of Babylon 5.100.122 Whore of Babylon 1 Grants +1.5 damage and +0.3 speed whenever Isaac has half a red heart or less (one red heart for Eve), ignoring any Soul or Black Hearts.
Removed in Repentance Dead Cat 5.100.81 Dead Cat 1 Sets Isaac's Red Heart containers to 1, but grants 9 extra lives. After dying, Isaac respawns with 1 Red Heart Container.
Added in Afterbirth Athame 5.100.408 Athame 1 When Isaac takes damage, a black ring briefly appears around him, dealing damage to all nearby enemies.
Added in Afterbirth Betrayal 5.100.391 Betrayal 1 Every time Isaac takes damage, a charm effect is applied to every enemy in the room, causing them to attack each other rather than Isaac.
Added in Afterbirth Black Powder 5.100.420 Black Powder 1 Isaac leaves a trail of black powder on the floor. Walking in a circle will spawn a pentagram symbol on the floor, which deals 10 damage per tick to any enemies inside it.
Added in Afterbirth Cambion Conception 5.100.412 Cambion Conception 1 After taking damage a certain amount of times, a permanent demonic familiar spawns.
Added in Afterbirth Empty Vessel 5.100.409 Empty Vessel 1 Grants two Black Hearts. While Isaac has no red hearts, grants flight and periodically grants an invincibility shield for a few seconds.
Added in Afterbirth Multidimensional Baby 5.100.431 Multidimensional Baby 1 Spawns a familiar that will follow Isaac's movements on a 2.5-second delay. Tears that pass through the baby will be doubled and increase in speed.
Added in Afterbirth My Shadow 5.100.433 My Shadow 1 Each time Isaac takes damage, inflicts fear on all enemies in the room and spawns a black friendly Charger that will attack enemies. The Charger will be killed if it is damaged too much.
Added in Afterbirth Succubus 5.100.417 Succubus 1 Spawns a flying familiar that bounces around the room with a black aura, dealing rapid damage to any enemies inside it. While standing in the aura, Isaac gains a 1.5x tear damage multiplier.
Added in Afterbirth † 7 Seals 5.100.526 7 Seals 1 Spawns a random Harbinger familiar that changes every 10 seconds. Harbingers have different behaviors and spawn themed Locusts.
Added in Afterbirth † Death's List 5.100.530 Death's List 1 Grants a pickup or stat upgrade if all enemies in a room are killed in the order they are marked.
Added in Afterbirth † Duality 5.100.498 Duality 1 Whenever a Devil or Angel Room would spawn after defeating a boss, both rooms spawn. Only one can be entered.
Added in Afterbirth † Lil Delirium 5.100.519 Lil Delirium 1 Grants a familiar that transforms into another random familiar every 10 seconds.
Added in Afterbirth † Shade 5.100.468 Shade 1 Spawns a shadow familiar that follows Isaac's movements on a 1 second delay and deals contact damage to enemies. After dealing enough damage, it is absorbed by Isaac and spawns friendly Chargers.
Added in Repentance 2Spooky 5.100.554 2Spooky 1 Enemies near Isaac are afflicted with fear.
Added in Repentance A Pound of Flesh 5.100.672 A Pound of Flesh 1 Devil deals now cost coins, shop items now cost health, and consumables in shops are free but surrounded by spikes.
Added in Repentance Blood Oath 5.100.569 Blood Oath 1 Stabs Isaac at the beginning of each floor, draining his red hearts. Increases damage and speed for the floor based on the amount drained.
Added in Repentance Brimstone Bombs 5.100.646 Brimstone Bombs 1 Gives Isaac +5 bombs and causes his bombs to fire 15►Brimstone Brimstone lasers in the cardinal directions upon exploding.
Added in Repentance Dark Prince's Crown 5.100.442 Dark Prince's Crown 1 When at exactly one Red Heart, grants +0.75 tears, +1.5 range, +1 tear height, +0.2 shot speed.
Added in Repentance False PHD 5.100.654 False PHD 1 Converts good pills into bad pills and identifies all pills. Bad pills now have secondary positive effects. Grants one Black Heart.
Added in Repentance Guppy's Eye 5.100.665 Guppy's Eye 1 Shows the contents of Chests, Sacks, and Fire Places before they're opened.
Added in Repentance Vengeful Spirit 5.100.702 Vengeful Spirit 1 After taking damage, spawns an orbital wisp that lasts for the entire floor, up to a maximum of six. They fire tears but do not block shots.
Full red heartFull red heart 2 Hearts Cost
Abaddon 5.100.230 Abaddon 1 Grants +1.5 damage, +0.2 speed. Removes all Red Heart containers, grants six Black Hearts, and adds a chance to shoot fear tears.
Brimstone 5.100.118 Brimstone 1 Tears are replaced by a laser beam that pierces through all enemies and obstacles in its path and deals high damage. Can only be fired after a short charge-up period.
Death's Touch 5.100.237 Death's Touch 1 +1.5 damage, -0.3 tears. Tears are replaced with large piercing scythes.
Judas' Shadow 5.100.311 Judas' Shadow 1 Adds an extra life; upon death, it respawns Isaac as Dark Judas with two Black Hearts.
Lil' Brimstone 5.100.275 Lil' Brimstone 1 Grants a familiar that shoots a thin Brimstone beam. Must charge like Brimstone before shooting.
Lord of the Pit 5.100.82 Lord of the Pit 1 Grants flight and +0.3 speed.
Mom's Knife 5.100.114 Mom's Knife 1 Isaac's tears are replaced by a knife that pierces enemies, can travel through obstacles and can hurt enemies while Isaac is holding it. Holding down the fire button before firing increases its range and power.
Spirit of the Night 5.100.159 Spirit of the Night 1 Grants spectral tears and flight.
The Pact 5.100.80 The Pact 1 Grants two Soul Hearts, +0.5 damage, and +0.7 tears.
Added in Afterbirth Incubus 5.100.360 Incubus 1 Spawns a demonic familiar that shoots tears identical to Isaac's in terms of damage, tears, and tear effects.
Added in Afterbirth Maw of the Void 5.100.399 Maw of the Void 1 Charged by firing for 2.5 seconds and when released, creates a black ring around Isaac that rapidly deals damage. Removed in Repentance +1 damage, the ring can cause enemies to drop Black Hearts.
Added in Afterbirth † Eye of Belial 5.100.462 Eye of Belial 1 Grants piercing tears. After piercing one enemy, tears start homing and deal double damage.
Added in Afterbirth † / Removed in Repentance Dark Prince's Crown 5.100.442 Dark Prince's Crown 1 When at exactly one Red Heart, grants +0.75 tears, +1.5 range, +1 tear height, +0.2 shot speed.
Added in Repentance Bloody Gust 5.100.695 Bloody Gust 1 When Isaac takes damage, he gains speed and tears for the rest of the floor.
Added in Repentance Bloody Lust 5.100.157 Bloody Lust 1 Increases Isaac's damage whenever he takes damage, up to six times. The bonus resets when entering a new floor.
Added in Repentance Dead Cat 5.100.81 Dead Cat 1 Sets Isaac's Red Heart containers to 1, but grants 9 extra lives. After dying, Isaac respawns with 1 Red Heart Container.
Added in Repentance Eye of the Occult 5.100.572 Eye of the Occult 1 Isaac's tears are now controlled mid-flight with tear controls. Also increases damage and range, but decreases shot speed.
Added in Repentance Lil Abaddon 5.100.679 Lil Abaddon 1 Spawns a familiar that charges a miniature Added in Afterbirth15►Maw of the Void Maw of the Void attack while Isaac shoots.
Added in Repentance Lusty Blood 5.100.411 Lusty Blood 1 Isaac's damage increases for the current room each time he kills an enemy.
Added in Repentance Ocular Rift 5.100.606 Ocular Rift 1 Gives Isaac the chance to fire tears that create rifts where they land, which damage nearby enemies and pull in enemies, pickups, and tears/shots from all sources.

Added in RepentanceThe Following items have special weights in this Item pool:

  • Forget Me Now and Mega Blast have a weight of 0.2 in the Devil Room Pool, making them 80% less likely to appear.
  • Void, Heartbreak, Berserk!, Dark Arts, Abyss, and Lemegeton have a weight of 0.5 in the Devil Room Pool, making them 50% less likely to appear.

Any items outside of the Devil Room item pool will have a price of 1 Red Heart or 3 Soul Hearts/Black Hearts. This can be caused either by obtaining Added in Afterbirth15►Chaos Chaos or exhausting the item pool, making 15►Breakfast Breakfast appear.

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