Binding of Isaac: Rebirth Wiki
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(except in Rebirth)

Items in this pool can be found in the Devil RoomDevil Room in Greed mode. All items can be bought for some number of Red Heart containers. If Isaac has no Red Heart containers, items can be bought for three Soul HeartSoul Hearts.

Activated Collectibles[ | ]

Name ID Icon Weight Price Description
The Book of Belial 5.100.34
The Book of Belial
3 rooms
1
Full red heart
(in Rebirth) +2 damage for the current room. Passively guarantees a Devil RoomDevil Room or Angel RoomAngel Room will appear while held.
(except in Rebirth) +2 damage for the current room. Passively increases the chance of finding a Devil RoomDevil Room or Angel RoomAngel Room while held.
The Book of Sin 5.100.97
The Book of Sin
4 rooms
1
Full red heart
Generates a random pickup, pill, card, or rune.
Guppy's Head 5.100.145
Guppy's Head
1 room
1
Full red heart
Spawns 2-4 friendly Blue Flies that damage enemies.
Guppy's Paw 5.100.133
Guppy's Paw
Unlimited
1
Full red heart
Upon use, converts one Red Heart Container into three Soul HeartSoul Hearts.
The Nail 5.100.83
The Nail
6 rooms
1
(except in Repentance)Full red heartFull red heart
(in Repentance)Full red heart
(except in Repentance) Gives one Soul HeartSoul Heart. For the current room; +0.7 damage, -0.18 speed, Isaac breaks rocks and deals contact damage.
(in Repentance) Gives half a Black HeartBlack Heart. For the current room; +2 damage, -0.18 speed, Isaac breaks rocks and deals contact damage.
The Necronomicon 5.100.35
The Necronomicon
4 rooms
1
Full red heart
Deals 40 damage to every enemy in the room.
Satanic Bible 5.100.292
Satanic Bible
6 rooms
1
Full red heartFull red heart
Gives one Black HeartBlack Heart. (in Repentance) Replaces the boss room item on the current floor with a Devil Deal.
Mega Blast 5.100.441
Mega Blast
12 rooms
0.2
Full red heart
Upon use, Isaac fires a laser similar to the one used by Mega Satan Head ingameMega Satan. This laser deals massive damage, lasts for approximately 15 seconds, and persists between rooms. Isaac is pushed backwards by the force of the laser while it is active.
(in Afterbirth † and Repentance) Book of the Dead 5.100.545
Book of the Dead
6 rooms
1
Full red heart
(except in Repentance) Creates a friendly BonyBony, Black BonyBlack Bony, or an orbital bone for each enemy killed in the current room.
(in Repentance)Creates a friendly BonyBony, Black BonyBlack Bony, Bone FlyBone Fly, RevenantRevenant, or an orbital bone for each enemy killed in the current room.
(in Afterbirth † and Repentance) Sacrificial Altar 5.100.536
Sacrificial Altar
One time use
1
(except in Repentance)Full red heartFull red heart
(in Repentance)Full red heart
Sacrifices up to 2 familiars and spawns an item for each familiar sacrificed. Converts all friendly spiders and flies into coins.
(in Repentance) Damocles 5.100.577
Damocles
One time use
1
Full red heartFull red heart
Spawns a sword above Isaac's head, which doubles all item pedestals. After Isaac takes damage, the sword can randomly fall at any point, instantly killing him.
(in Repentance) Gello 5.100.728
Gello
2 rooms
1
Full red heart
Spawns a demon familiar that's attached to Isaac and moves and fires in the direction Isaac shoots, using Isaac's damage, tears, range, shot speed, and special tear effects.
(in Repentance) Monster Manual 5.100.123
Monster Manual
6 rooms
1
Full red heart
(except in Repentance) Spawns a familiar from a specific selection for the current room.
(in Repentance) Spawns a familiar from a specific selection for the current floor.
(in Repentance) Sulfur 5.100.556
Sulfur
3 rooms
1
Full red heart
Grants Collectible Brimstone iconBrimstone for the current room.
(in Repentance) Abyss 5.100.706
Abyss
4 rooms
0.5
Full red heart
Destroys all items in the room and gives Isaac a unique locust familiar for each item destroyed. Some items generate locusts with special effects.
(in Repentance) Berserk! 5.100.704
Berserk!
With damage dealt
0.5
Full red heart
Causes Isaac to go berserk for 5 seconds, greatly increasing his speed, tears, and damage, but restricting him to using a melee weapon instead of his tears. This item charges by dealing damage to enemies instead of clearing rooms.
(in Repentance) Dark Arts 5.100.705
Dark Arts
6 seconds
0.5
Full red heart
Briefly grants +1 speed and makes Isaac invulnerable and intangible. When the effect ends, destroys all projectiles and damages all enemies Isaac ran through.
(in Repentance) Lemegeton 5.100.712
Lemegeton
6 rooms
0.5
Full red heart
Spawns a wisp representing a random passive item, which orbits Isaac but can be destroyed. While the wisp is alive, Isaac gains that item's effects. Generation uses the current room's item pool 25% of the time, otherwise a random pool.

Passive Collectibles[ | ]

Name ID Icon Weight Price Description
Abaddon 5.100.230 Abaddon
1
Full red heartFull red heart
(except in Repentance) +1.5 damage, +0.2 speed. Removes all Red Heart containers, grants six Black HeartBlack Hearts, and adds a chance to shoot fear tears.
(in Repentance) +1.5 damage, +0.2 speed. Grants two Black HeartBlack Hearts, converts all Red Heart Containers into Black Hearts, and adds a chance to shoot fear tears.
Athame 5.100.408 Athame
1
Full red heart
(except in Repentance) When Isaac takes damage, a damaging black ring briefly appears around him. This ring can cause enemies to drop Black HeartBlack Hearts.
(in Repentance) After Isaac kills an enemy, adds a luck-based chance to spawn a damaging black ring around them.
Betrayal 5.100.391 Betrayal
1
Full red heart
(except in Repentance) Charms all enemies in the room when Isaac takes damage.
(in Repentance) Enemies are able to damage each other. If an enemy is damaged by another enemy, they will attack that enemy instead of Isaac.
Black Powder 5.100.420 Black Powder
1
Full red heart
Isaac leaves a trail of black powder on the floor. Walking in a circle will spawn a pentagram symbol on the floor, which deals 10 damage per tick to any enemies inside it.
Ceremonial Robes 5.100.216 Ceremonial Robes
1
(except in Repentance)Full red heart
(in Repentance)Full red heartFull red heart
Grants 3 Black HeartBlack Hearts, and +1 damage.
Cambion Conception 5.100.412 Cambion Conception
1
Full red heart
After taking damage a certain amount of times, a permanent demonic familiar spawns.
Contract From Below 5.100.241 Contract From Below
1
Full red heart
Doubles the number of most room clear awards, but reduces the overall chance of getting one by 1/3.
Dark Matter 5.100.259 Dark Matter
1
Full red heart
+1 damage, adds a chance to shoot fear tears.
Dead Cat 5.100.81 Dead Cat
1
(except in Repentance)Full red heart
(in Repentance)Full red heartFull red heart
Sets Isaac's Red Heart Containers to 1, but grants 9 extra lives. After dying, Isaac respawns with 1 Red Heart Container.
Death's Touch 5.100.237 Death's Touch
1
Full red heartFull red heart
+1.5 damage, -0.3 tears. Tears are replaced with large piercing scythes.
Demon Baby 5.100.113 Demon Baby
1
Full red heart
Spawns a familiar that follows Isaac and automatically fires at enemies in its reach.
Empty Vessel 5.100.409 Empty Vessel
1
Full red heart
Grants two Black HeartBlack Hearts. While Isaac has no red hearts, grants flight and periodically grants an invincibility shield for a few seconds.
Gimpy 5.100.225 Gimpy
1
Full red heart
Gives chance of spawning a Soul HeartSoul Heart when taking damage. Enemies have a chance to drop a Half Red HeartHalf Red Heart after being killed.
Guppy's Collar 5.100.212 Guppy's Collar
1
Full red heart
Grants a permanent 50% chance to respawn with 1/2 of a Red HeartRed Heart after death.
Guppy's Hairball 5.100.187 Guppy's Hairball
1
Full red heart
Spawns a familiar that loosely follows behind Isaac, which blocks shots can be swung like a flail to damage enemies. Grows bigger by killing enemies.
Headless Baby 5.100.269 Headless Baby
1
Full red heart
Spawns a familiar that follows Isaac, leaving blood creep on the ground.
Incubus 5.100.360 Incubus
1
Full red heartFull red heart
Spawns a demonic familiar that shoots tears identical to Isaac's in terms of damage, tears, and tear effects.
Judas' Shadow 5.100.311 Judas' Shadow
1
Full red heartFull red heart
Upon death, respawns Isaac as Character Dark Judas iconDark Judas with two Black HeartBlack Hearts in the previous room.
Leech 5.100.270 Leech
1
Full red heart
Spawns a leech familiar that chases enemies, dealing ~3 damage per second. Heals a Half Red HeartHalf Red Heart whenever Leech kills an enemy.
Lord of the Pit 5.100.82 Lord of the Pit
1
Full red heartFull red heart
Grants flight and +0.3 speed.
A Lump of Coal 5.100.132 A Lump of Coal
1
Full red heart
The more distance tears travel, the more damage they will do.
The Mark 5.100.79 The Mark
1
Full red heart
(except in Repentance) Grants one Soul HeartSoul Heart, +1 damage, and +0.2 speed.
(in Repentance) Grants one Black HeartBlack Heart, +1 damage, and +0.2 speed.
Maw Of The Void 5.100.399 Maw Of The Void
1
Full red heartFull red heart
Charged by firing for 2.5 seconds and when released, creates a black ring around Isaac that rapidly deals damage. (except in Repentance) +1 damage, the ring can cause enemies to drop Black HeartBlack Hearts.
Mom's Knife 5.100.114 Mom's Knife
1
Full red heartFull red heart
Isaac's tears are replaced by a knife that pierces enemies, can travel through obstacles, and can hurt enemies while Isaac is holding it. Holding down the fire button before firing increases its range and power.
Multidimensional Baby 5.100.431 Multidimensional Baby
1
Full red heart
Spawns a familiar that will follow Isaac's movements on a 2.5-second delay. Tears that pass through the baby will be doubled and increase in speed.
My Shadow 5.100.433 My Shadow
1
Full red heart
(except in Repentance) Inflicts fear on all enemies in the room upon taking damage and spawns black friendly ChargerChargers that attack enemies.
(in Repentance)Spawns a shadow familiar that closely follows behind Isaac. It spawns a black friendly ChargerCharger whenever an enemy touches it.
Ouija Board 5.100.115 Ouija Board
1
Full red heart
Grants spectral tears that travel through obstacles (but not enemies). (in Repentance) +0.5 tears.
The Pact 5.100.80 The Pact
1
Full red heartFull red heart
(except in Repentance) Grants two Soul HeartSoul Hearts, +0.5 damage, and +0.7 tears.
(in Repentance) Grants two Black HeartBlack Hearts, +0.5 damage, and +0.7 tears.
Pentagram 5.100.51 Pentagram
1
Full red heart
+1 damage, increases Devil RoomDevil Room / Angel RoomAngel Room chance by 10%.
Rotten Baby 5.100.268 Rotten Baby
1
Full red heart
Spawns a familiar that spawns a Blue Fly when Isaac shoots. It can only have one Fly at a time.
Sacrificial Dagger 5.100.172 Sacrificial Dagger
1
Full red heart
Spawns a dagger orbital familiar, blocking enemy shots and dealing a high amount of damage to enemies in contact.
Sister Maggy 5.100.67 Sister Maggy
1
Full red heart
(except in Repentance) Spawns a familiar that follows Isaac around shooting tears that deal 3.5 damage.
(in Repentance) Spawns a familiar that follows Isaac around shooting tears that deal 6 damage.
Spirit of the Night 5.100.159 Spirit of the Night
1
Full red heartFull red heart
Grants spectral tears and flight.
Whore of Babylon 5.100.122 Whore of Babylon
1
Full red heart
Grants +1.5 Damage and +0.3 Speed whenever Isaac has a Half Red HeartHalf Red Heart or less.
(except in Repentance) Cube of Meat 5.100.73 Cube of Meat
1
Full red heart
Creates an orbital familiar. Collecting additional copies gives it the ability to shoot tears, then chase enemies to deal contact damage, then deal even more contact damage.
(except in Repentance) Dead Bird 5.100.117 Dead Bird
1
Full red heart
After Isaac takes damage, spawns a flying familiar that chases enemies for the current room, dealing ~4 damage per second.
(except in Repentance) Guppy's Tail 5.100.134 Guppy's Tail
1
Full red heart
Room Clear Awards have a 1/3 chance of being replaced with a ChestChest and a 2/9 chance being replaced with nothing.
(in Afterbirth † and Repentance) 7 Seals 5.100.526 7 Seals
1
Full red heart
Spawns a random Harbinger familiar that changes every 10 seconds. Harbingers have different behaviors and spawn themed Locusts.
(in Afterbirth † and Repentance) Dark Prince's Crown 5.100.442 Dark Prince's Crown
1
(except in Repentance)Full red heartFull red heart
(in Repentance)Full red heart
(except in Repentance) When at exactly one Red HeartRed Heart, +0.75 tears, +1.5 range, and +0.2 shot speed.
(in Repentance) When at exactly one Red HeartRed Heart, +2 fire rate, +1.5 range, and +0.2 shot speed.
(in Afterbirth † and Repentance) Eye of Belial 5.100.462 Eye of Belial
1
Full red heartFull red heart
Grants piercing tears. After piercing one enemy, tears start homing and deal double damage.
(in Afterbirth † and Repentance) Lil Delirium 5.100.519 Lil Delirium
1
Full red heart
Grants a familiar that transforms into another random familiar every 10 seconds.
(in Afterbirth † and Repentance) Little Horn 5.100.503 Little Horn
1
Full red heart
(except in Repentance) Adds a chance to fire a piercing tear that instantly kills any enemy that it touches.
(in Repentance) Adds a chance to fire a tear that summons Big Horn's hand to crush the first enemy it hits, instantly killing monsters or greatly damaging bosses.
(in Afterbirth † and Repentance) Shade 5.100.468 Shade
1
Full red heart
Spawns a shadow familiar that follows Isaac's movements on a 1 second delay and deals contact damage to enemies. After dealing enough damage, it is absorbed by Isaac and spawns friendly My ShadowChargers.
(in Afterbirth † and Repentance) Tarot Cloth 5.100.451 Tarot Cloth
1
Full red heart
Drops a random card or rune. (except in Repentance) Doubles the effects of most cards and runes. (in Repentance) Doubles the effects of tarot cards.
(in Repentance) 2Spooky 5.100.554 2Spooky
1
Full red heart
Enemies near Isaac are afflicted with fear.
(in Repentance) Azazel's Rage 5.100.699 Azazel's Rage
1
Full red heart
Isaac builds rage every time a room is cleared. After four rooms, fires a large Collectible Brimstone iconBrimstone laser when entering the next room.
(in Repentance) Backstabber 5.100.506 Backstabber
1
Full red heart
Isaac's tears deal double damage and inflict bleeding on enemies if they're facing away from Isaac.
(in Repentance) Blood Oath 5.100.569 Blood Oath
1
Full red heart
Stabs Isaac at the beginning of each floor, draining his Red HeartRed Hearts. Increases damage and speed for the floor based on the amount drained.
(in Repentance) Bloody Gust 5.100.695 Bloody Gust
1
Full red heart
The first 6 times Isaac takes damage on a given floor, he gains Speed and Fire Rate for the rest of the floor, up to a maximum of +1.02 and +3.00, respectively.
(in Repentance) Bloody Lust 5.100.157 Bloody Lust
1
Full red heart
Increases Isaac's damage whenever he takes damage, up to six times. The bonus resets when entering a new floor.
(in Repentance) Brimstone 5.100.118 Brimstone
1
Full red heartFull red heart
Tears are replaced by a laser beam that pierces through all enemies and obstacles in its path and deals high damage. Can only be fired after a short charge-up period.
(in Repentance) Brimstone Bombs 5.100.646 Brimstone Bombs
1
Full red heart
+5 BombBombs. Bombs fire four Collectible Brimstone iconBrimstone lasers in the cardinal directions upon exploding.
(in Repentance) Eye of the Occult 5.100.572 Eye of the Occult
1
Full red heartFull red heart
+1 damage, +2 range, -0.16 shot speed. Isaac's tears can be controlled mid-flight with tear controls.
(in Repentance) False PHD 5.100.654 False PHD
1
Full red heart
Converts good pills into bad pills and identifies all pills. Bad pills now have secondary positive effects. Grants one Black HeartBlack Heart.
(in Repentance) Guppy's Eye 5.100.665 Guppy's Eye
1
Full red heart
Shows the contents of ChestChests, Fire PlaceFire Places, Grab BagGrab Bags, and ShopkeeperShopkeepers before they're opened/destroyed.
(in Repentance) Hungry Soul 5.100.684 Hungry Soul
1
Full red heart
Enemies have a chance to spawn ghosts on death, which chase and deal contact damage to enemies and explode after a short time.
(in Repentance) Lil Abaddon 5.100.679 Lil Abaddon
1
Full red heart
Spawns a familiar that charges a miniature Collectible Maw Of The Void iconMaw Of The Void attack while Isaac shoots.
(in Repentance) Lusty Blood 5.100.411 Lusty Blood
1
Full red heartFull red heart
Isaac's damage increases for the current room each time he kills an enemy.
(in Repentance) Money = Power 5.100.109 Money = Power
1
Full red heart
Increases damage by 0.04 for every Pennycoin Isaac has, up to +3.96 damage at 99 coins.
(in Repentance) Ocular Rift 5.100.606 Ocular Rift
1
Full red heartFull red heart
Adds a chance to fire tears that create rifts where they land, which suck enemies, pickups, and shots towards them and damage enemies in the area.
(in Repentance) Purgatory 5.100.634 Purgatory
1
Full red heart
While in a room with enemies, spawns cracks on the ground. Walking over these cracks summons ghosts that launch themselves at enemies and explode.
(in Repentance) A Quarter 5.100.74 A Quarter
1
Full red heart
Gives Isaac 25 Pennycoins.
(in Repentance) Sanguine Bond 5.100.692 Sanguine Bond
1
Full red heart
Spawns a special set of spikes in the Devil RoomDevil Room. Taking damage from the spikes has a chance to grant a reward.
(in Repentance) Twisted Pair 5.100.698 Twisted Pair
1
Full red heartFull red heart
Spawns two familiars that float on either side of Isaac and fire tears that use his tears, range, shot speed, and tear effects, and scale with damage.
(in Repentance) Vengeful Spirit 5.100.702 Vengeful Spirit
1
Full red heart
After taking damage, spawns an orbital wisp that lasts for the entire floor, up to a maximum of six. They fire tears but do not block shots.
(in Repentance) Heartbreak 5.100.694 Heartbreak
0.5
Full red heart
Grants 3 broken hearts and +0.25 damage for every broken heart Isaac has. Every otherwise fatal hit will add 2 more until Isaac has nothing but broken hearts.
(in Repentance) Technology 5.100.68 Technology
0.2
Full red heart
Replaces tears with a piercing laser with unlimited range.


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