Re-rolling pickups duplicated by Rune of Jera, Diplopia and Crooked Penny will result on both the original item and the duplicate being the exact same pickup.
Can re-roll both items created by Options?, but only one can still be taken.
Golden Trinkets rerolled by D20 will cause the resulting pickup to have the golden effect applied to it. If this is a trinket, the affected trinket will act as a normal golden trinket would, otherwise the gold effect will do nothing and will disappear upon leaving and reentering the room.
Additionally, items spawned by chests with the gold effect applied will be golden as well, however other pickups dropped by chests will not be.
Can reroll coins dropped by Tainted Keeper into other pickups, but they will still disappear if not picked up quickly.
Strategy[ | ]
In Greed mode, the D20 is a one-item game breaker as long as the Shop has a Lil' Battery available. Leave behind as many coins and pickups in the arena as possible. After using the D20, avoid opening chests until the item has been recharged. Avoid collecting things that do not spawn pickups, help buy Lil' Batteries, or help open chests. This can often be repeated indefinitely, leading to collecting coins, bombs, and many pedestal items.
Due to how the D20 interacts with the Book of Virtues, this strategy will not work with Bethany, as using the D20 while playing as her will destroy all pickups in the room.
However, this can be avoided by removing Book of Virtues using Butter!
D Infinity can be used for this strategy if it is found.
Book of Virtues: Spawns wisps in the middle ring. In addition to summoning its specific wisp, instead of rerolling pickups, it will destroy all the pickups in the room and has a chance to give a random wisp for each pickup destroyed.
Safety Scissors: Bombing a Bomb Bum while possessing this trinket will convert the Troll Bombs he spawns into regular Bombs. This process can be repeated indefinitely for unlimited Bomb pickups. These Bomb pickups can then be rerolled with the D20.
Interactions[ | ]
Car Battery: Re-rolls twice instantly without any benefits.
When used to reroll pickups in Tainted Keeper's special shops, pickups may be rerolled into items instead.
In-game Footage[ | ]
Gallery[ | ]
3DS The icon of D20 as seen on the lower 3DS screen.
Trivia[ | ]
In the original The Binding of Isaac, the D20 was unlocked by beating Isaac as Isaac.