Binding of Isaac: Rebirth Wiki

Each time you reach a new floor, there is a small chance to receive a curse, making the floor much more difficult to complete. Each curse only lasts for the current floor. The possible curses are:

Curse Description
Curse of the Blind.png Curse of the Blind All items are replaced with a question mark and are not revealed until they are picked up.
Curse of Darkness.png Curse of Darkness The floor is much, much darker, and is only barely lit by the player's natural aura. Occasionally rooms will be filled with swirling clouds of what could be fireflies or glowing motes of dust. Fire, explosions, and lasers will all cast light as normal, as will red creep.

Added in Repentance The aura of light around Isaac is now much larger, but the darkness outside it is much darker.

Curse of the Lost.png Curse of the Lost Removes the map from the HUD. Same effect as the Amnesia pill.

Also increases the possible total room count of the current floor to the size of the next floor.

Curse of the Maze.png Curse of the Maze Entering a new room (including teleporting) will occasionally take Isaac to the wrong room, with a screen-shake and sound effect to indicate the jump. For example, entering the room on the right may instead take Isaac to the room on the left. Occasionally, discovered rooms can swap contents, without a screen-shake or sound effect.
Curse of the Unknown.png Curse of the Unknown Removes Isaac's health from the HUD, leaving the player unable to see how many hearts remain of any kind. Health will still be tracked as normal, including Soul Heart Soul Hearts, Black Heart Black Hearts, and Eternal Heart Eternal Hearts. When Isaac is down to half a heart, it is still marked by urine when entering a room.

Added in Repentance Also removes Isaac's Holy Mantle Holy Mantle icon from the HUD.

Curse of the Labyrinth.png Curse of the Labyrinth Appears only on the first floor of a chapter. Makes the floor an XL floor, which contains two Boss Room Boss Rooms, two items and counts as two floors. If this happens in either Basement Basement, Cellar Cellar, Added in Afterbirth or the Burning Basement Burning Basement, both Treasure Room Treasure Room doors will be unlocked.
Curse of the Cursed.png Curse of the Cursed Changes normal doors into cursed doors. Found only in the Cursed! challenge or enabling the Added in Afterbirth "CVRS ED" seed.
Added in Repentance Curse of the Giant.png Curse of the Giant Merges normal sized rooms into 2x2, 1x2, 2x1 or L-shaped rooms while narrow rooms are not affected(further confimation needed). This curse currently isn't achievable naturally in game.


Your odds of getting a curse vary with progression, increasing over time.

Unlocks Normal Hard
New Game 1/80 1/10
Killed Mom Mom 5 times 1/30 1/5
Everything's Terrible 1/10 1/3
Killed Isaac Isaac 1/5 1/2 (Added in Repentance1/3)
  • All curses have an equal, 1/6 chance of occurring.
    • If Curse of the Labyrinth is picked on a floor it cannot spawn on, such as the second floor of any chapter, Greed Mode, or on any chapters post-Womb, no curses will be active for the floor.
      • This makes the chance of getting cursed on floors without Curse of the Labyrinth 1/6, or 5/12 for Hard Mode.


  • Curse of the Labyrinth.png Curse of the Labyrinth can spawn the same boss in both rooms on one floor.
  • Because Curse of the Labyrinth causes the two floors in a chapter to merge, it is possible to lower your Devil Room Devil Room encounter chance in Basement Basement I, Cellar Cellar I, or Added in Afterbirth Burning Basement Burning Basement I.
  • With the Curse of the Labyrinth, it is possible to teleport into the second Boss Room Boss Room and completely skip the first.
  • Added in Repentance If Curse of the Labyrinth takes effect during Chapter 1, taking the door that spawns after the second boss room will lead to Downpour Downpour II or Dross Dross II.
  • Added in Repentance If Curse of the Labyrinth merges Downpour Downpour or Dross Dross, there will be two "mirror" Boss Rooms.
  • Added in Repentance If Curse of the Labyrinth merges Downpour Downpour, Dross Dross, Mines Mines, or Ashpit Ashpit into an XL floor, the special rooms leading to Added in RepentanceKnife Piece 1 Knife Piece 1 and Added in RepentanceKnife Piece 2 Knife Piece 2, and their associated gimmicks, will still appear.
    • Added in Repentance Only one of the "mirror" treasure rooms in Downpour Downpour and Dross Dross will contain the knife piece; the other will be empty.
  • Curse of Darkness.png Curse of Darkness can be made somewhat easier by increasing the gamma setting in the game's options.
    • Added in Repentance XIX - The Sun XIX - The Sun can now remove Curse of Darkness for the current floor.
    • The Added in AfterbirthNight Light Night Light can remove Curse of Darkness for the floor it's picked up. While it does not make the player immune to the Curse in floors after picking it up, the light beam it emits diminishes the drawback of low visibility.
  • Curse of the Unknown.png Curse of the Unknown does not affect The Lost The Lost, as he is, technically speaking, perpetually under its effect anyways.
    • Added in Repentance The Lost can no longer see whether the Holy Mantle Holy Mantle's shield has been broken in the current room.
  • Curse of the Maze.png Curse of the Maze can be used to enter locked rooms without spending Key Keys. It can also be used to enter Curse Room Curse Rooms without spending health, Arcade Arcades without spending coins, Bedrooms without spending Bomb Bombs, Secret Room Secret Rooms (without spending bombs), and Boss Room Boss Rooms. Be warned, though, as it can teleport Isaac elsewhere when trying to enter a Curse Room Curse Room, forcing him to take damage to enter it (unless the player has some form of flight).
  • When Curse of the Maze triggers, it takes into account the direction the room was exited through. For example, if Isaac leaves a room by a door on the right wall, it can only take Isaac to a room that has a door on its left wall. (also works with teleporting)
  • Curse of the Maze can only swap rooms that have doors in the same spots as each other, including (Super) Secret Room doors.
    • If you know two rooms swapped places and one of the rooms has a wall where the other had a door, a secret room is guaranteed to be there.
  • Curse of the Maze may otherwise interfere with teleportation cards, but Joker Joker is unaffected.
  • With Curse of the Maze active, using any form of extra life or revival item can put Isaac to a previously unvisited room.
  • Removed in Repentance Curse of the Maze can teleport Isaac to the same room he was just in.
    • Added in Repentance Curse of the Maze now only teleports Isaac into uncleared rooms.
  • XIX - The Sun XIX - The Sun and Rune of Ansuz Rune of Ansuz do not counteract the effect of Curse of the Lost.
  • With Curse of the Blind.png Curse of the Blind active, leaving and re-entering a room which had a revealed item will change the item back to a question mark.

3DS Curse of the Lost can be countered, as the player can draw a map on the touch screen.


  • Of the three curses that returned from Wrath of the Lamb, (Labyrinth, the Lost, and Darkness), two of them — Curse of the Lost.png Curse of the Lost and Curse of Darkness.png Curse of Darkness — have different effects from Rebirth onwards. Namely, the Curse of the Lost's old effect (which simply made the floor as big as a floor that was one 'tier' higher, meaning a Basement as big as The Caves, or a Depths as big as The Womb) was dropped entirely, the Curse of Darkness's old effect (removal of the map) was given to the Curse of the Lost, and the Curse of Darkness was given the dark-floor effect. Curse of the Labyrinth.png Curse of the Labyrinth, meanwhile, remained untouched.
  • Added in Repentance Curse of the Giant.png Curse of the Giant originated from the Antibirth mod, but cannot be encountered in-game without using mods or the Debug Console. This was because the room-combining aspect of the curse would often lead to buggy or unfair rooms.
    • A system was to be added that determined the fairness of a large room, such as limiting the number of enemies, but this proved to be too complicated to finish in time.
  • Added in Repentance There is another curse being used internally in the game, called Curse of the Mist. This is active inside the Added in Repentance Mother's Shadow Mother's Shadow area and is used to disable the player's items.


Bug Bug! Curse of the Maze.png Curse of the Maze can still take you to already explored rooms