Binding of Isaac: Rebirth Wiki
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Items in this pool can spawn in the Curse RoomCurse Room. This does not apply to Red Chests.

Activated Collectibles[ | ]

Name ID Icon Weight Description
Guppy's Head 5.100.145
Guppy's Head
1 room
1
Spawns 2-4 friendly Blue Flies that damage enemies.
Guppy's Paw 5.100.133
Guppy's Paw
Unlimited
1
Upon use, converts one Red Heart Container into three Soul HeartSoul Hearts.
(in Afterbirth † and Repentance) Sacrificial Altar 5.100.536
Sacrificial Altar
One time use
1
Sacrifices up to 2 familiars and spawns an item for each familiar sacrificed. Converts all friendly spiders and flies into coins.
(in Afterbirth † and Repentance) Plan C 5.100.475
Plan C
One time use
0.2
Kills all enemies in the room, then kills Isaac three seconds later.
(in Repentance) Flip 5.100.711
Flip
6 rooms
1
Item pedestals have a second uninteractable "ghostly" item behind them. Activating will flip the real and ghostly items around. If playing as Character Tainted Lazarus iconTainted Lazarus, also flips between them and Character Dead Tainted Lazarus iconDead Tainted Lazarus.
(in Repentance) Magic Skin 5.100.642
Magic Skin
6 rooms
1
Consumes one heart container or two Soul HeartSoul Hearts to spawn an item and give Isaac a broken heart container that can never be filled. If Magic Skin isn't being held after being used, it is very likely to replace any future items.
(in Repentance) Razor Blade 5.100.126
Razor Blade
Unlimited
1
Takes one Red HeartHeart of health and grants +1.2 damage for the current room. (in Repentance) Repeated uses in the same room only take half a heart.
(in Repentance) Red Key 5.100.580
Red Key
4 rooms
1
Creates a Red RoomRed Room adjacent to a viable wall, indicated by the outline of a door. These rooms have a 10% chance to be a special room.

Passive Collectibles[ | ]

Name ID Icon Weight Description
Black Candle 5.100.260 Black Candle
1
Prevents curses. Grants one Black HeartBlack Heart. Increases the chance for a Devil RoomDevil Room or Angel RoomAngel Room to appear.
Ceremonial Robes 5.100.216 Ceremonial Robes
1
Grants 3 Black HeartBlack Hearts, and +1 damage.
Contract From Below 5.100.241 Contract From Below
1
Doubles the number of most room clear awards, but reduces the overall chance of getting one by 1/3.
Dead Cat 5.100.81 Dead Cat
1
Sets Isaac's Red Heart Containers to 1, but grants 9 extra lives. After dying, Isaac respawns with 1 Red Heart Container.
Gimpy 5.100.225 Gimpy
1
Gives chance of spawning a Soul HeartSoul Heart when taking damage. Enemies have a chance to drop a Half Red HeartHalf Red Heart after being killed.
Goat Head 5.100.215 Goat Head
1
A Devil RoomDevil Room / Angel RoomAngel Room will always spawn after every boss fight, excluding the first floor and floors after Chapter 4.
Guppy's Collar 5.100.212 Guppy's Collar
1
Grants a permanent 50% chance to respawn with 1/2 of a Red HeartRed Heart after death.
Guppy's Tail 5.100.134 Guppy's Tail
1
Room Clear Awards have a 1/3 chance of being replaced with a ChestChest and a 2/9 chance being replaced with nothing.
The Mark 5.100.79 The Mark
1
(except in Repentance) Grants one Soul HeartSoul Heart, +1 damage, and +0.2 speed.
(in Repentance) Grants one Black HeartBlack Heart, +1 damage, and +0.2 speed.
The Pact 5.100.80 The Pact
1
(except in Repentance) Grants two Soul HeartSoul Hearts, +0.5 damage, and +0.7 tears.
(in Repentance) Grants two Black HeartBlack Hearts, +0.5 damage, and +0.7 tears.
Pentagram 5.100.51 Pentagram
1
+1 damage, increases Devil RoomDevil Room / Angel RoomAngel Room chance by 10%.
(except in Rebirth) Athame 5.100.408 Athame
1
(except in Repentance) When Isaac takes damage, a damaging black ring briefly appears around him. This ring can cause enemies to drop Black HeartBlack Hearts.
(in Repentance) After Isaac kills an enemy, adds a luck-based chance to spawn a damaging black ring around them.
(except in Rebirth) Curse of the Tower 5.100.371 Curse of the Tower
1
Upon taking damage, spawns six Troll BombTroll Bombs around the room, similar to the effect of XVI - The TowerXVI - The Tower.
(in Afterbirth † and Repentance) Dark Prince's Crown 5.100.442 Dark Prince's Crown
1
(except in Repentance) When at exactly one Red HeartRed Heart, +0.75 tears, +1.5 range, and +0.2 shot speed.
(in Repentance) When at exactly one Red HeartRed Heart, +2 fire rate, +1.5 range, and +0.2 shot speed.
(in Afterbirth † and Repentance) Euthanasia 5.100.496 Euthanasia
1
Adds a chance to fire needles that instantly kill basic enemies and deal triple damage to bosses. If a needle kills an enemy, it bursts into more tears/needles.
(in Afterbirth † and Repentance) Little Horn 5.100.503 Little Horn
1
(except in Repentance) Adds a chance to fire a piercing tear that instantly kills any enemy that it touches.
(in Repentance) Adds a chance to fire a tear that summons Big Horn's hand to crush the first enemy it hits, instantly killing monsters or greatly damaging bosses.
(in Afterbirth † and Repentance) Shade 5.100.468 Shade
1
Spawns a shadow familiar that follows Isaac's movements on a 1 second delay and deals contact damage to enemies. After dealing enough damage, it is absorbed by Isaac and spawns friendly My ShadowChargers.
(in Afterbirth † and Repentance) Tarot Cloth 5.100.451 Tarot Cloth
1
Drops a random card or rune. (except in Repentance) Doubles the effects of most cards and runes. (in Repentance) Doubles the effects of tarot cards.
(in Afterbirth †) Mom's Razor 5.100.508 Mom's Razor
1
Spawns an orbiting razor that deals contact damage and inflicts bleeding on enemies, causing them to slowly take damage over time.
(in Repentance) Blood Oath 5.100.569 Blood Oath
1
Stabs Isaac at the beginning of each floor, draining his Red HeartRed Hearts. Increases damage and speed for the floor based on the amount drained.
(in Repentance) Blood Puppy 5.100.565 Blood Puppy
1
Spawns a familiar that chases enemies. After killing enough enemies, it becomes more powerful but will also try to hurt Isaac, it will also generate Half Red HeartHalf Red Hearts on enemy kills. It can increase in power one more stage after killing even more enemies. Dealing enough damage to it returns it to normal.
(in Repentance) Guppy's Eye 5.100.665 Guppy's Eye
1
Shows the contents of ChestChests, Fire PlaceFire Places, Grab BagGrab Bags, and ShopkeeperShopkeepers before they're opened/destroyed.
(in Repentance) Sanguine Bond 5.100.692 Sanguine Bond
1
Spawns a special set of spikes in the Devil RoomDevil Room. Taking damage from the spikes has a chance to grant a reward.
(in Repentance) Vengeful Spirit 5.100.702 Vengeful Spirit
1
After taking damage, spawns an orbital wisp that lasts for the entire floor, up to a maximum of six. They fire tears but do not block shots.
(in Repentance) False PHD 5.100.654 False PHD
0.5
Converts good pills into bad pills and identifies all pills. Bad pills now have secondary positive effects. Grants one Black HeartBlack Heart.
(in Repentance) Heartbreak 5.100.694 Heartbreak
0.5
Grants 3 broken hearts and +0.25 damage for every broken heart Isaac has. Every otherwise fatal hit will add 2 more until Isaac has nothing but broken hearts.
(in Repentance) Vanishing Twin 5.100.697 Vanishing Twin
0.5
Spawns a familiar that becomes a clone of the floor's boss when entering the Boss RoomBoss Room. Defeating it drops an extra item.


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