Curse Room (Greed Mode Item Pool)

Items in this pool can spawn in the Curse Room in Greed mode. This does not apply to Red Chests.

Activated Collectibles[]

Name	ID	Weight	Description
Guppy's Head	5.100.145	1	Spawns 2-4 friendly Blue Flies that damage enemies.
Guppy's Paw	5.100.133	1	Upon use, converts one Red Heart Container into three Soul Hearts.
Magic Skin	5.100.642	1	Consumes one heart container or two soul hearts to spawn an item and give Isaac a broken heart container that can never be filled. If Magic Skin isn't being held after being used, it is very likely to replace any future items.
Razor Blade	5.100.126	1	On use, takes one heart of health and grants +1.2 damage for the current room.
Sacrificial Altar	5.100.536	1	Sacrifices up to 2 familiars and spawns an item from the Devil Room pool for each familiar sacrificed. Converts all friendly spiders and flies into coins.
Plan C	5.100.475	0.2	Kills all enemies in the room, then kills Isaac three seconds later.

Passive Collectibles[]

Name	ID	Weight	Description
Cube of Meat	5.100.73	1	Creates an orbital familiar. Collecting additional copies gives it the ability to shoot tears, then chase enemies to deal contact damage, then deal even more contact damage.
Dead Cat	5.100.81	1	Sets Isaac's Red Heart Containers to 1, but grants 9 extra lives. After dying, Isaac respawns with 1 Red Heart Container.
Guppy's Collar	5.100.212	1	Grants a permanent 50% chance to respawn with 1/2 of a Red Heart after death.
Guppy's Tail	5.100.134	1	Room Clear Awards have a 1/3 chance of being replaced with a Chest and a 1/3 chance being replaced with nothing.
Athame	5.100.408	1	When Isaac takes damage, a black ring briefly appears around him, dealing damage to all nearby enemies.
Black Candle	5.100.260	1	Prevents curses. Grants one Black Heart. Increases the chance for a Devil or Angel Room to appear.
Blood Oath	5.100.569	1	Stabs Isaac at the beginning of each floor, draining his red hearts. Increases damage and speed for the floor based on the amount drained.
Blood Puppy	5.100.565	1	Spawns a familiar that chases enemies. After killing enough enemies, it becomes more powerful but will also try to hurt Isaac. Attacking it returns it to normal.
Ceremonial Robes	5.100.216	1	Grants 3 Black Hearts, and +1 damage.
Curse of the Tower	5.100.371	1	Upon taking damage, spawns six Troll Bombs around the room, similar to the effect of XVI - The Tower.
Dark Prince's Crown	5.100.442	1	When at exactly one Red Heart, increases tears, range, tear height, and shot speed.
Euthanasia	5.100.496	1	Adds a chance to fire needles that instantly kill basic enemies and deal triple damage to bosses. If a needle kills an enemy, it bursts into more tears/needles.
Gimpy	5.100.225	1	Gives chance of spawning a Soul Heart when taking damage. Enemies have a chance to drop a Half Red Heart after being killed.
Little Horn	5.100.503	1	Adds a chance to fire a piercing tear that instantly kills any enemy that it touches. Adds a chance to fire a tear that summons Big Horn's hand to crush the first enemy it hits, instantly killing monsters or greatly damaging bosses.
The Mark	5.100.79	1	Grants one Soul Heart, +1 damage, and +0.2 speed. Grants one Black Heart, +1 damage, and +0.2 speed.
The Pact	5.100.80	1	Grants two Soul Hearts, +0.5 damage, and +0.7 tears. Grants two Black Hearts, +0.5 damage, and +0.7 tears.
Pentagram	5.100.51	1	+1 damage, increases Devil Room / Angel Room chance by 10%.
Sanguine Bond	5.100.692	1	Spawns a special set of spikes in the Devil Room. Taking damage from the spikes has a chance to grant a reward.
Shade	5.100.468	1	Spawns a shadow familiar that follows Isaac's movements on a 1 second delay and deals contact damage to enemies. After dealing enough damage, it is absorbed by Isaac and spawns friendly Chargers.
Tarot Cloth	5.100.451	1	Drops a random card or rune. Doubles the effects of most cards and runes. Doubles the effects of tarot cards.
Vengeful Spirit	5.100.702	1	After taking damage, spawns an orbital wisp that lasts for the entire floor, up to a maximum of six. They fire tears but do not block shots.
False PHD	5.100.654	0.5	Converts good pills into bad pills and identifies all pills. Bad pills now have secondary positive effects. Grants one Black Heart.
Heartbreak	5.100.694	0.5	Grants 3 broken hearts and +0.25 damage for every broken heart Isaac has. Every otherwise fatal hit will add 2 more until Isaac has nothing but broken hearts.