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Cube of Meat is an unlockable passive item.

Effects[ | ]

  • Spawns an Orbital Familiar around Isaac which blocks shots and deals contact damage.
    • (except in Repentance) It deals 105 damage per second.
    • (in Repentance) It deals 52.5 damage per second.
  • Each subsequent Cube of Meat obtained are combined with the first one (increasing its 'level'), changing its characteristics:
    • Level 2: Gives the orbital the ability to shoot tears that deal 3.5 damage.
      • (except in Repentance) It shoots once every second.
      • (in Repentance) It shoots once every 0.73 seconds.
    • Level 3: Changes it from an orbital to a Meat Boy that chases nearby enemies dealing contact damage.
      • (except in Repentance) It deals 8.75 contact damage per second.
      • (in Repentance) It deals 12.5 contact damage per second.
    • Level 4: Increases the size of the Meat Boy larger and increases its damage.
      • (except in Repentance) It deals 13.75 contact damage per second.
      • (in Repentance) It deals 25 contact damage per second.
    • The fifth Cube of Meat will create a new Level 1 cube, and start the cycle again.

Notes[ | ]

  • Multiple Cubes of Meat can be collected in a single run.
  • (in Repentance) The orbital orbits Isaac significantly faster.
  • Boss Famine ingameFamine, Boss Pestilence ingamePestilence, Boss War ingameWar, and Boss Death ingameDeath will always drop either a Collectible Ball of Bandages iconBall of Bandages or Cube of Meat. After the first one drops, further Harbingers will only drop that same one and never the other for the duration of the run.
  • The ticking rate for Meat Boys' contact damage causes them to often deal damage twice once they touch an enemy, making their first second of DPS up to 1.5x higher than normal.

Synergies[ | ]

Interactions[ | ]

  • (in Afterbirth † and Repentance)Duct TapeDuct Tape: Familiar will stay in place relative to Isaac at levels 1 and 2. No effect at levels 3 and 4.
  • Pretty Fly: Cube of Meat will replace one if Isaac already has 3 Pretty Flies. If the Cube of Meat reaches level 3 or 4, the Pretty Fly will come back until another Cube of Meat orbital is obtained.

Unlockable Achievements[ | ]

In-game Footage[ | ]

Gallery[ | ]

Trivia[ | ]

  • The Cube of Meat is a reference to the game Super Meat Boy, developed by Edmund McMillen, creator of The Binding of Isaac.
  • The pickup quote is a reference to the Pokémon series catchphrase "Gotta catch 'em all."
  • (except in Repentance) Cube of Meat is found in 9 item pools, the highest count amongst all items, due to the fact that it appears in all of Greed Mode's item pools.


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