Non-tainted characters can only transform into other non-tainted characters, and tainted characters can only transform into other tainted characters.
However, Ankh, Lazarus' Rags, or Judas' Shadow allows a tainted character to become ???, Lazarus, or Dark Judas (besides their respective tainted forms) allowing the Clicker to transform them into other non-tainted characters. Note that there is no way for a non-tainted character to become a tainted character.
It is possible for the Clicker to choose the same character as the one that is already being played as, making it seem like the item created no effect at all.
Transforming into a new character does not grant Isaac the starting items of the new character unless they are inherent to the character. For example, transforming into Cain does not grant Lucky Foot.
All health will be lost when changing into The Lost. Changing from The Lost to any other character will leave them with a Half Soul Heart.
Keeper will always start with 2 Coin Heart containers. Bone and Half Soul/Black Hearts will be rounded up to 1 or 2 filled coins. Red Hearts are not rounded, which allows him to have half Coin Hearts. Changing from Keeper to any other character will turn his Coin Hearts into Red Hearts.
All Red Heart containers are converted to Coin Heart containers when transforming into Keeper, with a minimum of 2 and up to a maximum of 3. Only red hearts will determine if the coin heart containers are filled or not, and Soul/Black hearts will be converted into blue flies. One coin heart container will be filled if he would otherwise have no health. Changing from Keeper to any other character will turn his Coin Hearts into Red Hearts.
Changing into The Forgotten will not affect The Soul's health. Red Hearts are converted into Bone Hearts. Soul/Black Hearts will be lost. He will gain an empty Bone Heart if he would otherwise have no health.
All soul hearts will be converted to soul charges when changing into Bethany. She will gain one full Red Heart container if she would otherwise have no health. Changing from Bethany to any other character will convert her soul charges into soul hearts.
If Isaac only had empty heart containers before changing to Bethany, doing so kills her instantly.
Heart Containers will be divided evenly and split up when changing into Jacob and Esau. Changing from Jacob and Esau to any other character will leave them with Jacob and Esau's combined health.
Activating Clicker typically only consumes passive items, but with Schoolbag, it can consume the item in the other activated item slot if that item was the most recently collected.
Tainted Cain can craft the Clicker and other useful items and then use Clicker to change characters. In this way, runs started as Tainted Cain can be useful to complete other characters' completion marks, even when Tainted Cain's own completion marks are finished. Although Clicker will only turn tainted characters into other tainted characters, Tainted Cain can also craft Ankh, Lazarus' Rags, or Judas' Shadow and die to become a non-tainted character then use the Clicker to change into other non-tainted characters.
Changing into Eden or Tainted Eden will not use tokens. Additionally, (Tainted) Eden's base stats will be the same as Isaac's if he wasn't the character selected at the start of the run.
Changing into Jacob and Esau will randomly distribute items between the two. Changing from Jacob and Esau to any other character will leave them with Jacob and Esau's combined items. Changing into or from Jacob and Esau will drop the currently held consumables like pills, cards etc. on the floor, but will keep trinkets (if they were held by Jacob or any other character). Esau's trinkets will always be dropped on the ground when changing to a different character.
Changing into Tainted Isaac will remove every passive item except the 8 oldest items Isaac holds.
Changing into Tainted Lazarus will give every passive item to only one of the forms.
Changing from Tainted Lazarus into another character will only keep the items of the form that used Clicker.
Changing into a character who holds a pocket active and changing again without picking up another passive item will cause the clicker to remove the pocket active instead of a passive.
If Dead Cat was the last item to be picked up, Clicker will remove individual lives instead of the entire item.
If Halo of Flies was the last item to be picked up, Clicker will only remove one fly at a time (including Pretty Flies obtained from pills and Slot Machines) instead of the entire item.
Synergies[ | ]
The Book of Belial + Birthright as Judas / Dark Judas: Replaces the most recently acquired item with [[{{{page}}}|Pentagram]] instead of removing it. Birthright's effects will also change to that of the character transformed into.
Car Battery: Isaac will transform twice and have the last two picked up items removed.
Rock Bottom: Stat upgrades given by removed items are retained, and the best stats of each character you turn into are retained, possibly creating some powerful characters, like Tainted Keeper with all the Berserk stats of Tainted Samson.
In-game Footage[ | ]
Trivia[ | ]
Clicker is a TV remote, and the static overlay when the item is used references when a channel is switched.
Bugs[ | ]
Bug!
If Lazarus dies, becomes Lazarus Risen, and then uses Clicker to become another character, the character will have Lazarus' hair and freckles. This also works with reviving items such as Ankh.
Bug!
If Clicker is used in The Soul form of The Forgotten, it is possible to be turned into another Forgotten. Both Forgottens have independent health bars and can be swapped between, but no Soul form exists anymore. Turning into any other character does not cause the bug.[Check ingame]
Bug!
If Clicker turns the player into Jacob and Esau, after collecting Eden's Blessing previously in the run, any items that would have been normally gained at the beginning of the next run, are instead given to Jacob and Esau instantly. This makes it so that no free random items are gained at the start of the next run.
Bug!
If Clicker is used as Tainted Lazarus while holding Birthright, the active form will click to another character, but the other form will still be in its ghostly form due to the effects of Birthright. Clearing rooms will alternate between the activity of the ghostly form, switching it's vulnerability and health from the main character, and placing clicker in the pocket item slot. Exiting and re-entering the game during this will cause a softlock unless the player has a second controller, which if not available, will make the player unable to continue the run.
Dark Judas and 
Bug!
Lazarus dies, becomes Lazarus Risen, and then uses Clicker to become another character, the character will have Lazarus' hair and freckles. This also works with reviving items such as 
Ankh.
The Forgotten, it is possible to be turned into another Forgotten. Both Forgottens have independent health bars and can be swapped between, but no Soul form exists anymore. Turning into any other character does not cause the bug.[Check ingame]
If Clicker turns the player into 
Jacob and Esau, after collecting 
Eden's Blessing previously in the run, any items that would have been normally gained at the beginning of the next run, are instead given to 
Tainted Lazarus while holding 
Birthright, the active form will click to another character, but the other form will still be in its ghostly form due to the effects of Birthright. Clearing rooms will alternate between the activity of the ghostly form, switching it's vulnerability and health from the main character, and placing clicker in the pocket item slot. Exiting and re-entering the game during this will cause a softlock unless the player has a second controller, which if not available, will make the player unable to continue the run.
The Binding of Isaac: Rebirth
