Chemical Peel

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Chemical   Peel
Item icon
Item altar
"DMG up"
Table dividing line 1.png
Item ID
5.100.154
Character Appearance
Character appearance
Table dividing line 2.png
Table dividing line 3.png
Collection Grid
Removed in Afterbirth(page 2, column 1, row 6)
Added in Afterbirth(page 2, column 11, row 2)

Chemical Peel is a passive item.

Effects[edit | edit source]

  • +2 flat damage to tears fired from Isaac's left eye.

Notes[edit | edit source]

  • The damage bonus is unaffected by both positive and negative damage multipliers.
  • Cain has a 50% chance of firing a shot with the effects of Chemical Peel whenever he fires.
  • 15►Blood Clot Blood Clot applies to the same eye and the effects stack.
    • Generally every interaction and synergy that applies to Chemical Peel also applies to Blood Clot. See its page for any differences to what is listed here.

Synergies[edit | edit source]

  • 15►20/20 20/20/15►The Inner Eye The Inner Eye/15►Mutant Spider Mutant Spider: Every other set of tears has the Chemical Peel effect.
  • 15►Brimstone Brimstone: The entire laser has a high chance to have the Chemical Peel effect, with no visual difference.
  • 15►Dr. Fetus Dr. Fetus: The damage bonus applies to every bomb, with no visual difference.
  • 15►Epic Fetus Epic Fetus: The missiles have a high chance to deal 40 points extra damage, with no visual difference.
  • Added in Afterbirth †15►Lead Pencil Lead Pencil: All tears in the tear barrage will gain the Chemical Peel effect.
  • 15►The Ludovico Technique The Ludovico Technique: The tear flashes between normal and the higher-damaging Chemical Peel tear.
  • 15►Mom's Knife Mom's Knife: Each tick of the Knife's damage has a high chance to gain the bonus, with no visual difference.
  • 15►Tech.5 Tech.5: Chemical Peel has a chance to apply to the laser, with no visual difference.
  • 15►Technology Technology: Lasers have a high chance to gain extra damage, with no visual difference.
  • 15►Technology 2 Technology 2: Every tear fired has Chemical Peel applied to it, but the laser is unaffected.

Interactions[edit | edit source]

  • Added in Afterbirth15►Incubus Incubus: Has a 50% chance of firing a shot with the Chemical Peel effect.
  • 15►Sad Bombs Sad Bombs: The last type of tear fired is used for the burst.
  • Added in Afterbirth15►Tech X Tech X: Overrides Chemical Peel.
  • Added in Afterbirth †15►Varicose Veins Varicose Veins: The last type of tear fired is used for the burst.

In-game Footage[edit | edit source]

Seeds[edit | edit source]

PC Normal mode only 4AA3 QSMJ (Treasure Room adjacent to spawn)

PC Normal mode only S9CH XAMT (Treasure Room adjacent to spawn)

PS4 VXMQ Y96F (First Treasure Room adjacent to spawn)


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