Binding of Isaac: Rebirth Wiki
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Binding of Isaac: Rebirth Wiki

Womb Womb[]

Boss Blastocyst portrait.png
Boss The Bloat portrait.png
Boss Daddy Long Legs portrait.png
Boss Lokii portrait.png
Blastocyst The Bloat Removed in Repentance Daddy Long Legs Removed in Repentance Lokii
Boss Mama Gurdy portrait.png
Boss Mr. Fred portrait.png
Boss Scolex portrait.png
Boss Teratoma portrait.png
Mama Gurdy Mr. Fred Scolex Teratoma Removed in Repentance
Boss Death portrait.png
Boss Triachnid portrait.png
Boss Conquest portrait.png
Boss The Headless Horseman portrait.png
Death Needs to be unlocked Triachnid Removed in Repentance Needs to be unlocked Conquest Needs to be unlocked The Headless Horseman Needs to be unlocked
Boss The Fallen portrait.png
Boss The Matriarch portrait.png
Boss Sisters Vis portrait.png
The Fallen Devil Room Icon.png The Matriarch Added in Afterbirth † Needs to be unlocked Sisters Vis Added in Afterbirth † / Removed in Repentance Needs to be unlocked

Double Trouble[]

Double Trouble Bosses
Boss Dingle portrait.png
Boss The Cage portrait.png
Boss The Fallen portrait.png
Boss The Gate portrait.png
(Double Trouble)
Dingle
(Double Trouble)
The Cage
(Double Trouble)
The Fallen
(Double Trouble)
The Gate
Boss Gurdy portrait.png
Boss Dangle portrait.png
Boss Little Horn portrait.png
(Double Trouble)
Gurdy
(Double Trouble)
Dangle Added in Afterbirth Needs to be unlocked
(Double Trouble)
Little Horn Added in Afterbirth Needs to be unlocked

Utero Utero[]

Boss Blastocyst portrait.png
Boss The Bloat portrait.png
Boss Daddy Long Legs portrait.png
Boss Lokii portrait.png
Blastocyst Removed in Repentance The Bloat Daddy Long Legs Lokii
Boss Mama Gurdy portrait.png
Boss Mr. Fred portrait.png
Boss Teratoma portrait.png
Boss The Fallen portrait.png
Mama Gurdy Removed in Repentance Mr. Fred Removed in Repentance Teratoma The Fallen Devil Room Icon.png
Boss Death portrait.png
Boss Triachnid portrait.png
Boss Conquest portrait.png
Boss The Headless Horseman portrait.png
Death Needs to be unlocked Triachnid Needs to be unlocked Conquest Needs to be unlocked The Headless Horseman Needs to be unlocked
Boss The Matriarch portrait.png
Boss Sisters Vis portrait.png
The Matriarch Added in Afterbirth † / Removed in Repentance Needs to be unlocked Sisters Vis Added in Afterbirth † Needs to be unlocked

Double Trouble[]

Double Trouble Bosses
Boss The Cage portrait.png
Boss The Fallen portrait.png
Boss The Gate portrait.png
(Double Trouble)
The Cage
(Double Trouble)
The Fallen
(Double Trouble)
The Gate
Boss Gurdy portrait.png
Boss Loki portrait.png
Boss Little Horn portrait.png
(Double Trouble)
Gurdy
(Double Trouble)
Loki
(Double Trouble)
Little Horn Added in Afterbirth Needs to be unlocked

Scarred Womb Scarred Womb Added in Afterbirth[]

Boss Blastocyst portrait.png
Boss The Bloat portrait.png
Boss Daddy Long Legs portrait.png
Boss Mama Gurdy portrait.png
Blastocyst The Bloat Removed in Repentance Daddy Long Legs Removed in Repentance Mama Gurdy
Boss Scolex portrait.png
Boss Teratoma portrait.png
Boss Death portrait.png
Boss Conquest portrait.png
Scolex Teratoma Removed in Repentance Death Needs to be unlocked Conquest Needs to be unlocked
Boss Triachnid portrait.png
Boss The Headless Horseman portrait.png
Boss The Fallen portrait.png
Boss The Matriarch portrait.png
Triachnid Needs to be unlocked The Headless Horseman Needs to be unlocked The Fallen Devil Room Icon.png The Matriarch Added in Afterbirth † Needs to be unlocked
Boss Sisters Vis portrait.png
Boss Lokii portrait.png
Boss Mr. Fred portrait.png
Sisters Vis Added in Afterbirth † Needs to be unlocked Lokii Added in Repentance Mr. Fred Added in Repentance

Double Trouble[]

Double Trouble Bosses
Boss Gurdy portrait.png
(Double Trouble)
Gurdy

Final Boss[]

Mom's Heart will always appear in the second floor of this chapter or in the last boss room if Curse of the Labyrinth is active. Once It Lives is unlocked, it will appear instead of Mom's Heart.

Boss Mom's Heart portrait.png
Boss It Lives portrait.png
Mom's Heart It Lives Needs to be unlocked

Greed mode only Womb Womb Added in Afterbirth[]

Notes[]


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