Binding of Isaac: Rebirth Wiki
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WombWomb[ | ]

Boss Blastocyst
Boss Lokii
Boss Mama Gurdy
Boss Mr. Fred
Blastocyst Lokii Mama Gurdy Mr. Fred
Boss Scolex
Boss The Bloat
Boss Daddy Long Legs
Boss Triachnid
Scolex The Bloat (except in Repentance) Daddy Long Legs (except in Repentance) Triachnid (except in Repentance) Needs to be unlocked
Boss Teratoma
Boss Death
Boss Conquest
Boss Headless Horseman
Teratoma (except in Repentance) Death Needs to be unlocked Conquest Needs to be unlocked Headless Horseman Needs to be unlocked
Boss The Fallen
Boss The Matriarch
Boss Sisters Vis
The Fallen Devil Room Icon The Matriarch (in Afterbirth † and Repentance) Needs to be unlocked Sisters Vis (in Afterbirth †) Needs to be unlocked

Double Trouble[ | ]

Double Trouble Bosses
Boss Dingle
Boss The Cage
Boss The Fallen
Boss The Gate
(Double Trouble)
Dingle
(Double Trouble)
The Cage
(Double Trouble)
The Fallen
(Double Trouble)
The Gate
Boss Gurdy
Boss Dangle
Boss Little Horn
(Double Trouble)
Gurdy
(Double Trouble)
Dangle (except in Rebirth) Needs to be unlocked
(Double Trouble)
Little Horn (except in Rebirth) Needs to be unlocked

UteroUtero[ | ]

Boss Lokii
Boss The Bloat
Boss Daddy Long Legs
Boss Triachnid
Lokii The Bloat Daddy Long Legs Triachnid Needs to be unlocked
Boss Teratoma
Boss Mr. Fred
Boss Mama Gurdy
Boss Blastocyst
Teratoma Mr. Fred (except in Repentance) Mama Gurdy (except in Repentance) Blastocyst (except in Repentance)
Boss Death
Boss Conquest
Boss Headless Horseman
Boss The Fallen
Death Needs to be unlocked Conquest Needs to be unlocked Headless Horseman Needs to be unlocked The Fallen Devil Room Icon
Boss Sisters Vis
Boss The Matriarch
Sisters Vis (in Afterbirth †) Needs to be unlocked The Matriarch (in Afterbirth †) Needs to be unlocked

Double Trouble[ | ]

Double Trouble Bosses
Boss The Cage
Boss The Fallen
Boss The Gate
(Double Trouble)
The Cage
(Double Trouble)
The Fallen
(Double Trouble)
The Gate
Boss Gurdy
Boss Loki
Boss Little Horn
(Double Trouble)
Gurdy
(Double Trouble)
Loki
(Double Trouble)
Little Horn (except in Rebirth) Needs to be unlocked

(except in Rebirth)Scarred WombScarred Womb[ | ]

Boss Blastocyst
Boss Mama Gurdy
Boss Scolex
Boss Triachnid
Blastocyst Mama Gurdy Scolex Triachnid Needs to be unlocked
Boss Daddy Long Legs
Boss Teratoma
Boss The Bloat
Boss Death
Daddy Long Legs (except in Repentance) Teratoma (except in Repentance) The Bloat (except in Repentance) Death Needs to be unlocked
Boss Conquest
Boss Headless Horseman
Boss The Fallen
Boss The Matriarch
Conquest Needs to be unlocked Headless Horseman Needs to be unlocked The Fallen Devil Room Icon The Matriarch (in Afterbirth † and Repentance) Needs to be unlocked
Boss Sisters Vis
Boss Lokii
Boss Mr. Fred
Sisters Vis (in Afterbirth †) Needs to be unlocked Lokii (in Repentance) Mr. Fred (in Repentance)

Double Trouble[ | ]

Double Trouble Bosses
Boss Gurdy
(Double Trouble)
Gurdy

Final Boss[ | ]

Mom's Heart will always appear in the second floor of this chapter or in the last boss room if Curse of the Labyrinth is active. Once It Lives is unlocked, it will appear instead of Mom's Heart.

Boss Mom's Heart
Boss It Lives
Mom's Heart It Lives Needs to be unlocked

Notes[ | ]


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