Binding of Isaac: Rebirth Wiki
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Binding of Isaac: Rebirth Wiki

Depths Depths[]

Boss The Adversary portrait.png
Boss The Cage portrait.png
Boss The Gate portrait.png
Boss Loki portrait.png
The Adversary Removed in Repentance The Cage The Gate Loki
Boss Monstro II portrait.png
Boss War portrait.png
Boss Gish portrait.png
Boss The Headless Horseman portrait.png
Monstro II War Needs to be unlocked Gish Needs to be unlocked The Headless Horseman Needs to be unlocked
Boss The Fallen portrait.png
Boss Brownie portrait.png
Boss Sisters Vis portrait.png
Boss Reap Creep portrait.png
The Fallen Devil Room Icon.png Brownie Added in Afterbirth Needs to be unlocked Sisters Vis Added in Afterbirth † Needs to be unlocked Reap Creep Added in Repentance

Double Trouble[]

Double Trouble Bosses
Boss Chub portrait.png
Boss Gurdy Jr. portrait.png
Boss The Haunt portrait.png
(Double Trouble)
Chub
(Double Trouble)
Gurdy Jr.
(Double Trouble)
The Haunt
Boss The Hollow portrait.png
Boss The Husk portrait.png
Boss Larry Jr. portrait.png
(Double Trouble)
The Hollow
(Double Trouble)
The Husk
(Double Trouble)
Larry Jr.
Boss The Wretched portrait.png
Boss Little Horn portrait.png
Boss Rag Man portrait.png
(Double Trouble)
The Wretched
(Double Trouble)
Little Horn Added in Afterbirth Needs to be unlocked
(Double Trouble)
Rag Man Added in Afterbirth Needs to be unlocked

Necropolis Necropolis[]

Boss The Adversary portrait.png
Boss The Bloat portrait.png
Boss The Gate portrait.png
Boss Loki portrait.png
The Adversary The Bloat The Gate Removed in Repentance Loki
Boss Mask of Infamy portrait.png
Boss War portrait.png
Boss The Headless Horseman portrait.png
Boss The Fallen portrait.png
Mask of Infamy War Needs to be unlocked The Headless Horseman Needs to be unlocked The Fallen Devil Room Icon.png
Boss Brownie portrait.png
Boss Sisters Vis portrait.png
Boss The Pile portrait.png
Brownie Added in Afterbirth Needs to be unlocked Sisters Vis Added in Afterbirth † Needs to be unlocked The Pile Added in Repentance

Double Trouble[]

Double Trouble Bosses
Boss Blighted Ovum portrait.png
Boss The Haunt portrait.png
Boss The Husk portrait.png
Boss Larry Jr. portrait.png
(Double Trouble)
Blighted Ovum
(Double Trouble)
The Haunt
(Double Trouble)
The Husk
(Double Trouble)
Larry Jr.
Boss Dangle portrait.png
Boss Little Horn portrait.png
Boss Rag Man portrait.png
(Double Trouble)
Dangle Added in Afterbirth Needs to be unlocked
(Double Trouble)
Little Horn Added in Afterbirth Needs to be unlocked
(Double Trouble)
Rag Man Added in Afterbirth Needs to be unlocked

Dank Depths Dank Depths Added in Afterbirth[]

Boss The Adversary portrait.png
Boss Loki portrait.png
Boss Monstro II portrait.png
Boss War portrait.png
The Adversary Removed in Repentance Loki Monstro II War Needs to be unlocked
Boss Gish portrait.png
Boss The Headless Horseman portrait.png
Boss The Fallen portrait.png
Boss Brownie portrait.png
Gish Needs to be unlocked The Headless Horseman Needs to be unlocked The Fallen Devil Room Icon.png Brownie Added in Afterbirth Needs to be unlocked
Boss Sisters Vis portrait.png
Boss The Cage portrait.png
Boss The Gate portrait.png
Boss Reap Creep portrait.png
Sisters Vis Added in Afterbirth † Needs to be unlocked The Cage Added in Repentance The Gate Added in Repentance Reap Creep Added in Repentance

Double Trouble[]

Double Trouble Bosses
The Haunt
Boss Little Horn portrait.png
(Double Trouble)
The Haunt
(Double Trouble)
Little Horn Added in Afterbirth Needs to be unlocked

Final Boss[]

Mom will always appear in the second floor of this chapter or in the last boss room if Curse of the Labyrinth is active.

Boss Mom portrait.png
Mom

Notes[]


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