Binding of Isaac: Rebirth Wiki

Celtic Cross is an unlockable passive item.


  • Grants a chance to trigger the Book of Shadows Book of Shadows effect upon taking damage, creating a shield that nullifies all types of damage for 7 seconds.


  • The base chance of creating the protective shield is 20%
  • The activation chance of this item depends on the Luck stat and goes up to 100% at 27 Luck.
  • The shield negates health loss from Blood Donation Machine.png Blood Donation Machines and Devil Beggar.png Devil Beggars.
  • Does not prevent Heart Container loss from Health Down pills or Devil Room Devil Room Deals.
  • Does not prevent damage from IV Bag IV Bag.


  • Added in RepentanceThe Polaroid The Polaroid, Virgo Virgo: Can trigger at the same time as The Polaroid or Virgo, cumulating to up to 22 seconds of shield.

In-game Footage[]


  • In Galicia, Celtic crosses are usually found on top of granaries as a protective measure against any kind of evil. They are also commonly found among Celtic nations today and historically.
  • This item is functionally almost identical to Virgo Virgo, minus the pill conversion effect.


PC Normal mode only 864T K7DP (Treasure Room adjacent to spawn)

PC ZDS6 BYQN (First floor Treasure Room)

PC QDYL E0W7 (First floor Treasure Room)

PS4 4KLV R17F (First floor Treasure Room)

PC Vita DL4N WV3P (First floor Treasure Room)

Switch Greed mode only Q8RY S40K (First Golden Treasure Room)

Switch Normal mode only YYHR 0T8Z (First floor Treasure Room)