Binding of Isaac: Rebirth Wiki
Binding of Isaac: Rebirth Wiki

The Cathedral is one of two unlockable floors following Womb Womb/Utero Utero/Added in Afterbirth Scarred Womb Scarred Womb, the other being Sheol Sheol. After defeating Mom's Heart, an Angel Room may spawn containing a beam of light leading upwards to the Cathedral. Unlocking and defeating It Lives will always spawn a beam of light leading to the Cathedral, as well as a trapdoor leading to Sheol.

The Cathedral has only one floor, featuring mostly undead and/or holy enemies, and the boss is always Isaac.

Monsters[]

Entity ID Description
Angelic Baby
Angelic Baby
38.1.0 Slowly floats towards Isaac and fires three spread shots. Occasionally teleports and reappears elsewhere.
Bony
Bony
227.0 Wanders around the room and throws a bone at Isaac when he is in sight.
Death's Head
Death's Head
212.0 Invulnerable enemy that moves diagonally around the room, dealing contact damage. Dies when the room is cleared.
Clot
Clot
15.1 Randomly wanders around the room, firing 4 tar shots in the ordinal directions.
Pale Fatty
Pale Fatty
208.2 Slowly walks towards Isaac. Occasionally farts and shoots 6 blood shots in all directions. Has a chance to turn into a Blubber or Half Sack upon death.
Fat Sack
Fat Sack
209.0 Slowly walks towards Isaac. Occasionally leaps off-screen and attempts to land on Isaac, leaving a puddle of Red Creep and shooting 6 blood shots in all directions where it lands. Has a chance to turn into a Blubber or Half Sack upon death.
Floating Knight
Floating Knight
254.0 Behaves like the Knight but slower, and can fly over all obstacles.
Gazing Globin
Gazing Globin
24.1 Quickly chases Isaac, dealing a full heart of contact damage. Upon taking enough damage, it collapses into a pile of goo, which will slide away from Isaac and can be killed. Will regenerate after a short period of time if not killed quickly.
Hanger
Hanger
90.0 Floats around the room, firing 3 spread blood shots at Isaac. Upon damaging Isaac, Isaac drops 2 coins on the ground but loses 3. Spawns with an Eternal Fly circling around it.
Keeper
Keeper
86.0 Hops around the room, firing 2 blood shots in a V formation at Isaac. Upon damaging Isaac, Isaac drops 2 coins on the ground but loses 3.
Leech
Leech
55.0 Quickly charges towards Isaac when he gets in its line of sight.
Holy Leech
Holy Leech
55.2 Quickly charges towards Isaac when he gets in its line of sight. Explodes upon death. Spawns with an Eternal Fly circling it, which instantly dies when the Holy Leech explodes.
Mom's Hand
Mom's Hand
213.0 Falls from the ceiling. If it lands on Isaac, it deals damage and teleports the player back to the spawn room of the floor. Entering a room containing Mom's Hand will warn the player with Mom's laugh.
Ragling
Ragling
246.0 Quickly leaps towards Isaac and deals contact damage. Randomly shoots two purple shots that orbit around it.
Rotty
Rotty
226.1 Slowly walks towards Isaac, leaving short-lasting Red Creep behind itself. Spawns a Bony or two Attack Flies upon death.
Spit
Spit
61.1 Flies slowly towards Isaac, firing an Ipecac shot towards Isaac upon death.
Psy Tumor
Psy Tumor
253.0 Moves around the room diagonally, occasionally firing 6 homing shots in all directions. Fires more often upon getting damaged.
Psychic Horf
Psychic Horf
248.0 Stationary enemy that fires a homing shot at Isaac when he gets in range of them.
Psychic Maw
Psychic Maw
26.2 Slowly floats towards Isaac, firing homing shots at him when he is in their range. Spawns with an Eternal Fly orbiting around it.
Wizoob
Wizoob
219.0 Disappears, then appears near Isaac and spits a cluster of spectral tears at him.
Lil' Haunt
Lil' Haunt
260.0 Floats toward Isaac and occasionally fires a blood shot at him, predicting his movements.
Slide
Slide
44.1 Quickly slides towards Isaac when he gets in its line of sight, then moves slowly back to its original position. Cannot be destroyed.
Stone Grimace
Stone Grimace
42.0 Stationary and invulnerable monster that occasionally fires a blood shot at Isaac. Stops firing when room is cleared.
Cross Stone Shooter
Cross Stone Shooter
Added in Afterbirth †
202.10 Stationary and invulnerable monster that continuously fires shots in four directions, alternating between cardinal and ordinal.
Holy Eye
Holy Eye
Added in Repentance
60.2 Rapidly summons several beams of light around Isaac every few seconds.
Holy Mulligan
Holy Mulligan
Added in Repentance
22.2 Wanders around the room, avoiding Isaac and spawning Small Angelic Babies if he gets close. Spawns 1-2 Embryos upon death.
Bishop
Bishop
Added in Repentance
805.0 Shields all enemies in the room, preventing them from taking damage. Fires shots in the cardinal directions when it takes damage.
Holy Bony
Holy Bony
Added in Repentance
227.1 Wanders around the room, throwing a bone at Isaac when he is in sight. The thrown bone leaves behind a blue flame that deals contact damage, blocks Isaac’s shots, and despawns after some time.
Mullighoul
Mullighoul
Added in Repentance
817.1 Wanders around the room, avoiding Isaac and spawning Willos if he gets close. Spawns 1-2 Willos upon death.
Degraded Bosses

Boss[]

Boss Isaac.png
Isaac

Notes[]

  • Added in Afterbirth † Some rooms contain Angel Statues that can be bombed to summon the Angels and acquire key pieces.
  • If a trapdoor appears, it will lead to The Chest.

Trivia[]

  • In the original Binding of Isaac, the windows along the walls were much larger and had different patterns resembling Isaac and a crucifix.
  • One of the interpretations of this floor's theme Everlasting Hymn includes the sentence "Harm yourself and God will grant you strength" many consider this translation "Too extreme" or somehow having no parallels with this game's story, however all the original endings (based on the items Isaac collects) end with Isaac finding several objects and using them to harm himself, which indeed does increase his power in-game

Music[]

The music for the Cathedral is titled Everlasting Hymn.

Binding of Isaac: Rebirth OST


SmallIsaac.pngChaptersSmallIsaac.png
Chapter 1 Chapter 2 Chapter 3 Chapter 4 Optional Chapter 5 Chapter 6 Endgame
Normal and hard modes only Stage Basement icon.png Stage Caves icon.png Stage Depths icon.png Stage Womb icon.png Stage Sheol icon.png
Sheol


Stage Cathedral icon.png
Cathedral
Stage Dark Room icon.png
Dark Room


Stage Chest icon.png
The Chest
The Basement The Caves The Depths The Womb
Added in Afterbirth Added in Afterbirth †
Stage Cellar icon.png Stage Catacombs icon.png Stage Necropolis icon.png Stage Utero icon.png ??? Stage The Void icon.png
The Cellar The Catacombs Necropolis Utero ??? The Void
Added in Afterbirth Added in Afterbirth Added in Afterbirth Added in Afterbirth
Stage Burning Basement icon.png Stage Flooded Caves icon.png Stage Dank Depths icon.png Stage Scarred Womb icon.png
Burning Basement Flooded Caves Dank Depths Scarred Womb
Added in Repentance Added in Repentance Added in Repentance Added in Repentance Added in Repentance
Stage Downpour.png Stage Mines icon.png Stage Mausoleum icon.png Stage Corpse icon.png Stage Home icon.png
Downpour Mines Mausoleum Corpse Home
Added in Repentance Added in Repentance Added in Repentance
Stage Dross icon.png Stage Ashpit icon.png Stage Gehenna icon.png
Dross Ashpit Gehenna
Added in Afterbirth
Greed and greedier modes only
Added in Afterbirth Added in Afterbirth
Stage Basement icon.png Stage Caves icon.png Stage Depths icon.png Stage Womb icon.png Stage Sheol icon.png The Shop Ultra Greed
The Basement The Caves The Depths The Womb Sheol The Shop Ultra Greed
The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth
Achievements Achievements Attributes Attributes Bosses Bosses TarotCard.png Cards and Runes Challenges Challenges Chapters Chapters
Characters Characters MainPageBabies.png Co-op Items Items Item pools Item pools Monsters Monsters Objects Objects
Pickups Pickups Pills Pills Rooms Rooms Seeds Seeds Transformations Transformations Trinkets Trinkets