Binding of Isaac: Rebirth Wiki
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Cards and runes are usable items with a wide variety of effects. They take up the same slot as Pills.

Runes and special cards are unlocked by completing challenges.

Cards[ | ]

Major Arcana Cards[ | ]

When on the ground, these cards look like: TarotCard

Name ID Icon Message Description
0 - The Fool 5.300.1 0 - The Fool Where journey begins Teleports Isaac back to the starting room of the floor that he is currently on.
I - The Magician 5.300.2 I - The Magician May you never miss your goal (except in Repentance) Grants homing tears for the current room.
(in Repentance) Grants homing tears and +3 Range for the current room.
II - The High Priestess 5.300.3 II - The High Priestess Mother is watching you Mom's dismembered leg stomps on the enemy with the most health, dealing 300 damage and destroying obstacles in the area. If used in an empty room or during the Boss Mom ingameMom fight, stomps Isaac instead. (in Afterbirth † and Repentance)Isaac can move to avoid the stomp.
III - The Empress 5.300.4 III - The Empress May your rage bring power Triggers the Collectible Whore of Babylon iconWhore of Babylon effect (+1.5 Damage, +0.3 Speed) for the current room, regardless of Isaac's health total.
IV - The Emperor 5.300.5 IV - The Emperor Challenge me! Teleports Isaac into the Boss RoomBoss Room.
V - The Hierophant 5.300.6 V - The Hierophant Two prayers for the lost Drops 2 full Soul HeartSoul Hearts on the ground.
VI - The Lovers 5.300.7 VI - The Lovers May you prosper and be in good health Drops 2 full Red HeartRed Hearts on the ground.
VII - The Chariot 5.300.8 VII - The Chariot May nothing stand before you Gives invulnerability and +0.28 speed for six seconds, removing the ability to shoot tears and replacing it with the ability to deal contact damage to enemies.
VIII - Justice 5.300.9 VIII - Justice May your future become balanced Drops a random type of Heart, KeyKey, BombBomb and Coin pickup on the ground.
IX - The Hermit 5.300.10 IX - The Hermit May you see what life has to offer Teleports Isaac to the ShopShop.
X - Wheel of Fortune 5.300.11 X - Wheel of Fortune Spin the wheel of destiny Creates a Slot MachineSlot Machine or Fortune Telling MachineFortune Telling Machine near Isaac.
XI - Strength 5.300.12 XI - Strength May your power bring rage Grants the effects of Collectible Magic Mushroom iconMagic Mushroom (minus the health restoration) for one room. The added Red Heart container is not removed if doing so would kill Isaac.
XII - The Hanged Man 5.300.13 XII - The Hanged Man May you find enlightenment Grants flight for the duration of the room.
XIII - Death 5.300.14 XIII - Death Lay waste to all that oppose you Deals 40 damage to all enemies in the room.
XIV - Temperance 5.300.15 XIV - Temperance May you be pure in heart Creates a Blood Donation MachineBlood Donation Machine near Isaac. (except in Rebirth) Spawns a Devil BeggarDevil Beggar instead in Greed mode.
XV - The Devil 5.300.16 XV - The Devil Revel in the power of darkness Grants +2 Damage for the current room.
XVI - The Tower 5.300.17 XVI - The Tower Destruction brings creation Drops 6 Troll BombTroll Bombs randomly around the room.
XVII - The Stars 5.300.18 XVII - The Stars May you find what you desire Teleports Isaac to the Treasure RoomTreasure Room. Randomly chooses a Treasure Room if there is an active Curse of the LabyrinthCurse of the Labyrinth. (in Repentance) If there is a PlanetariumPlanetarium, teleports Isaac there instead.
XVIII - The Moon 5.300.19 XVIII - The Moon May you find all you have lost Teleports Isaac to the Secret RoomSecret Room. Opens one random wall inside the Secret Room, so Isaac can leave even if he doesn't have any BombBombs. Randomly chooses a Secret Room if there are multiple (via (in Afterbirth † and Repentance)Fragmented CardFragmented Card or (in Repentance)Collectible Luna iconLuna).
XIX - The Sun 5.300.20 XIX - The Sun May the light heal and enlighten you Restores Isaac to full health, deals 100 damage to all enemies in the room, and reveals the map for the current floor, except for the Super Secret RoomSuper Secret Room (in Repentance) and Ultra Secret RoomUltra Secret Room. (in Repentance) Removes Curse of DarknessCurse of Darkness for the current floor.
XX - Judgement 5.300.21 XX - Judgement Judge lest ye be judged Spawns a BeggarBeggar or a Devil BeggarDevil Beggar near Isaac. Has a 2% chance to spawn a (in Repentance) Battery BumBattery Bum, (in Repentance) Rotten BeggarRotten Beggar, Key MasterKey Master, or (except in Rebirth) Bomb BumBomb Bum instead.
XXI - The World 5.300.22 XXI - The World Open your eyes and see Reveals the entire floor, except for the Super Secret RoomSuper Secret Room (in Repentance) and Ultra Secret RoomUltra Secret Room.

(in Repentance) Reversed Major Arcana Cards[ | ]

These cards share the same names as their counterparts (barring the question marks at the end of their names), but have the sprite upside-down, a different message, the narrator sound clip reversed, and give different effects.

When on the ground, these cards look like: ReverseTarotCard

Name ID Icon Unlock method Message Description
0 - The Fool? 5.300.56 0 - The Fool? The Fool Defeat Ultra Greedier as Character Tainted Lost iconTainted Lost Let go and move on Drops all Hearts and pickups Isaac currently possesses on the floor, leaving Isaac at half a heart. Pickups may be dropped as items such as Collectible A Quarter iconA Quarter and Collectible Boom! iconBoom!.
I - The Magician? 5.300.57 I - The Magician? The Magician Defeat Ultra Greedier as Character Tainted Judas iconTainted Judas May no harm come to you Grants a repelling blue aura for one minute, like Collectible The Soul iconThe Soul but stronger and with a wider area of effect.
II - The High Priestess? 5.300.58 II - The High Priestess? The High Priestess Defeat Ultra Greedier as Character Tainted Lilith iconTainted Lilith Run Boss Mom ingameMom's leg starts stomping down repeatedly (targeting Isaac, not the enemies) for one minute, like holding Collectible Broken Shovel 1 iconBroken Shovel.
III - The Empress? 5.300.59 III - The Empress? The Empress Defeat Ultra Greedier as Character Tainted Eve iconTainted Eve May your love bring protection Grants 2 temporary Red Heart Containers, +1.5 Fire Rate and -0.1 Speed for one minute, along with Character Magdalene iconMagdalene's hairstyle. The effect does not stack with itself. When the effect ends, if the removal of the Heart Containers would kill Isaac, he is left with one instead.
IV - The Emperor? 5.300.60 IV - The Emperor? The Emperor Defeat Ultra Greedier as Character Tainted ??? iconTainted ??? May you find a worthy opponent Teleports Isaac into an extra Boss RoomBoss Room from the boss pool two floors deeper than the current floor (but never a final boss). The boss will drop a reward. Exiting the room returns Isaac to where he used the card.
V - The Hierophant? 5.300.61 V - The Hierophant? The Hierophant Defeat Ultra Greedier as Character Tainted Bethany iconTainted Bethany Two prayers for the forgotten Drops 2 Bone HeartBone Hearts on the ground.
VI - The Lovers? 5.300.62 VI - The Lovers? The Lovers Defeat Ultra Greedier as Character Tainted Magdalene iconTainted Magdalene May your heart shatter to pieces Creates a random item from the current room's item pool. Turns one Red Heart Container or two Soul HeartSoul Hearts into a Broken Heart.
VII - The Chariot? 5.300.63 VII - The Chariot? The Chariot Complete Hot Potato (challenge #42) May nothing walk past you Isaac becomes an invincible statue with 4x fire rate for 10 seconds. The statue can be nudged slightly by moving and is affected by knockback.
VIII - Justice? 5.300.64 VIII - Justice? Justice Complete Cantripped (challenge #43) May your sins come back to torment you Creates 2 to 4 Locked ChestLocked Chests near Isaac.
IX - The Hermit? 5.300.65 IX - The Hermit? The Hermit Complete Red Redemption (challenge #44) May you see the value of all things in life Turns items and pickups in the room into Coins, matching their normal shop price. If there is nothing to sell, drops a PennyPenny.
X - Wheel of Fortune? 5.300.66 X - Wheel of Fortune? Wheel of Fortune Defeat Ultra Greedier as Character Tainted Cain iconTainted Cain Throw the dice of fate Invokes a random Dice RoomDice Room effect.
XI - Strength? 5.300.67 XI - Strength? Strength Defeat Ultra Greedier as Character Tainted Samson iconTainted Samson May you break their resolve All enemies in the room are weakened, becoming slow and taking double damage. The effect lasts up to one minute or until the room is left.
XII - The Hanged Man? 5.300.68 XII - The Hanged Man? The Hanged Man Defeat Ultra Greedier as Character Tainted Keeper iconTainted Keeper May your greed know no bounds Isaac turns visually into Character Keeper iconKeeper for 30 seconds, with triple shot and -0.1 Speed. Killed enemies drop random Coins.
XIII - Death? 5.300.69 XIII - Death? Death Defeat Ultra Greedier as Character Tainted Forgotten iconTainted Forgotten May life spring forth from the fallen Creates a friendly Bony or temporary bone orbital for each enemy killed in the current room.
XIV - Temperance? 5.300.70 XIV - Temperance? Temperance Complete DELETE THIS (challenge #45) May your hunger be satiated Forces Isaac to eat 5 random Pills in quick succession.
XV - The Devil? 5.300.71 XV - The Devil? The Devil Defeat Ultra Greedier as Character Tainted Azazel iconTainted Azazel Bask in the light of your mercy Invokes Collectible The Bible iconThe Bible (which can kill Boss Mom ingameMom). Grants Flight and spawns a Collectible Seraphim iconSeraphim familiar for 30 seconds.
XVI - The Tower? 5.300.72 XVI - The Tower? The Tower Defeat Ultra Greedier as Character Tainted Apollyon iconTainted Apollyon Creation brings destruction Creates 7 clusters of random rocks and other obstacles. Spawned clusters will often contain tinted rocks, with the possibility of finding more than one in the same room. The pathways between exits can't be blocked.
XVII - The Stars? 5.300.73 XVII - The Stars? The Stars Defeat Ultra Greedier as Character Tainted Isaac iconTainted Isaac May your loss bring fortune Removes Isaac's oldest passive item (ignoring starting items) and creates 2 random items from the current room's item pool. Does nothing if Isaac has no items.
XVIII - The Moon? 5.300.74 XVIII - The Moon? The Sun and the Moon Defeat Ultra Greedier as Character Tainted Jacob iconTainted Jacob May you remember lost memories Teleports Isaac to the Ultra Secret RoomUltra Secret Room. The pathway back to the normal rooms will be made of Red RoomRed Rooms.
XIX - The Sun? 5.300.75 XIX - The Sun? The Sun and the Moon Defeat Ultra Greedier as Character Tainted Jacob iconTainted Jacob May the darkness swallow all around you Gain Collectible Spirit of the Night iconSpirit of the Night and +1.5 Damage for the current floor. Turns Isaac's Red Hearts into Bone Hearts, but they revert once the effect ends. Also causes Curse of DarknessCurse of Darkness that cannot be dispelled.
XX - Judgement? 5.300.76 XX - Judgement? Judgement Defeat Ultra Greedier as Character Tainted Lazarus iconTainted Lazarus May you redeem those found wanting Creates a Shop Restock MachineShop Restock Machine near Isaac.
XXI - The World? 5.300.77 XXI - The World? The World Defeat Ultra Greedier as Character Tainted Eden iconTainted Eden Step into the abyss Creates a trap door which always leads to a Crawl SpaceCrawl Space.

Playing Cards[ | ]

When on the ground, these cards look like: FaceCard

Name ID Icon Unlock method Message Description
2 of Clubs 5.300.23 2 of Clubs Always available Item multiplier Doubles Isaac's BombBombs. If he has no bombs, gives him 2 instead.
2 of Diamonds 5.300.24 2 of Diamonds Always available Item multiplier Doubles Isaac's PennyPenny. If he has no coins, gives him 2 instead.
2 of Spades 5.300.25 2 of Spades Always available Item multiplier Doubles Isaac's KeyKeys. If he has no keys, gives him 2 instead.
2 of Hearts 5.300.26 2 of Hearts Always available Item multiplier Doubles Isaac's current number of Red HeartRed Hearts. Doesn't add new Red Heart containers, just fills empty ones. If Isaac has only empty Red Heart containers, he is healed for 1 Red Heart. (in Repentance) Doubles Character Tainted Bethany iconTainted Bethany's Blood Charges.
(in Afterbirth † and Repentance) Ace of Clubs 5.300.27 Ace of Clubs Hat trick! Get a 3-win streak Convert all Turns all Pickups, Chests, and (in Repentance) non-boss enemies in the room into random Bomb pickups, including Troll BombTroll Bombs.
(in Afterbirth † and Repentance) Ace of Diamonds 5.300.28 Ace of Diamonds ZIP! Defeat The Lamb in under 20 minutes Convert all Turns all Pickups, Chests, and (in Repentance) non-boss enemies in the room into random Coin pickups.
(in Afterbirth † and Repentance) Ace of Spades 5.300.29 Ace of Spades It's the Key Defeat Boss The Lamb ingameThe Lamb without taking Hearts, Coins, or Bombs through the entire run. Letting certain familiars (e.g. Collectible Bum Friend iconBum Friend, Collectible Dark Bum iconDark Bum, (except in Rebirth)Collectible Bumbo iconBumbo or (in Repentance)Collectible Lil Portal iconLil Portal) or bosses (e.g. (in Repentance) Boss Bumbino ingameBumbino) pick up the consumables fails this condition as well. Convert all Turns all Pickups, Chests, and (in Repentance) non-boss enemies in the room into random Key pickups.
(in Afterbirth † and Repentance) Ace of Hearts 5.300.30 Ace of Hearts Living on the edge Complete a Chapter (floors I and II) after BasementBasement, start-to-finish, with only half a Heart total (can use Character The Lost iconThe Lost) Convert all Turns all Pickups, Chests, and (in Repentance) non-boss enemies in the room into random Hearts.
Joker 5.300.31 Joker Always available ??? Teleports Isaac to the Devil RoomDevil Room or Angel RoomAngel Room.
Suicide King 5.300.46 Suicide King Suicide King Complete Suicide King (challenge #7) A true ending? Kills Isaac and spawns lots of Pickups, items, and/or Chests in the same room.
(in Repentance) Queen of Hearts 5.300.79 Queen of Hearts Queen of Hearts Defeat Mega Satan as Character Tainted Magdalene iconTainted Magdalene <3 Drops 1-20 full Red HeartRed Hearts on the ground.

Magic: The Gathering Cards[ | ]

When on the ground, these cards look like: (in Rebirth and Afterbirth) FaceCard    (in Afterbirth †) MagicCard (in Repentance) MagicCardRepentance

Name ID Icon Unlock method Message Description
Chaos Card 5.300.42 Chaos Card Chaos Card Complete Demo Man (challenge #9) ??? Throws the card in the direction Isaac is moving, which opens doors, breaks obstacles, and instantly kills any enemy in its path.
(in Afterbirth † and Repentance) Huge Growth 5.300.52 Huge Growth Huge Growth Increase in size 5 times in a single run via Collectible Magic Mushroom iconMagic Mushroom, "One makes you larger" pills, XI - StrengthXI - Strength, etc. Become immense! (except in Repentance) For the current room, makes Isaac larger, allows him to crush obstacles he walks on, and grants +7 flat Damage and +30 Range.
(in Repentance) For the current room, makes Isaac larger, allows him to crush obstacles he walks on, and grants +7 flat Damage and +3 Range.
(in Afterbirth † and Repentance) Ancient Recall 5.300.53 Ancient Recall Ancient Recall Use Cards and Runes 20 times Draw 3 cards Spawns 3 random cards.
(in Afterbirth † and Repentance) Era Walk 5.300.54 Era Walk Era Walk Add both the Collectible Broken Watch iconBroken Watch and the Collectible Stop Watch iconStop Watch to your collection Savor the moment For the current room, enemies are slowed, Isaac's speed is increased by 0.50, and his shot speed is decreased by 1.00.

Credit Card[ | ]

When on the ground, this card looks like: (in Rebirth and Afterbirth) FaceCard    (in Afterbirth † and Repentance) CreditCard

Name ID Icon Unlock method Message Description
Credit Card 5.300.43 Credit Card Credit Card Complete Cursed! (challenge #10) Charge it! Makes all pickups and items that cost money or health in the room free.

Other Playing Cards[ | ]

When on the ground, these cards look like: FaceCard

Name ID Icon Unlock method Message Description
Rules Card 5.300.44 Rules Card Rules Card Complete Glass Cannon (challenge #11) ??? Displays a cryptic statement on the screen, similar to a Fortune Telling MachineFortune Telling Machine. These messages (often) provide hints on bosses, bonus areas, etc.
(except in Rebirth) ? Card 5.300.48 ? Card Always available Double active When used, copies the effect of Isaac's currently held activated collectible.

Card Against Humanity[ | ]

When on the ground, this card looks like: (in Rebirth and Afterbirth) FaceCard    (in Afterbirth † and Repentance) HumanityCard

Name ID Icon Unlock method Message Description
A Card Against Humanity 5.300.45 A Card Against Humanity Card Against Humanity Complete When Life Gives You Lemons (challenge #12) Something stinks... Covers the entire room with PoopPoop. The process is not instant, and the room will not get filled if Isaac leaves before it's done filling.

(except in Rebirth) Monopoly Card[ | ]

When on the ground, this card looks like: (in Rebirth and Afterbirth) FaceCard    (in Afterbirth † and Repentance) ChanceCard

Name ID Icon Unlock method Message Description
Get out of Jail Free Card 5.300.47 Get out of Jail Free Card Get out of Jail Free Card Complete SPEED! (challenge #22) Open Sesame Upon use, opens all doors in the current room, exactly like Collectible Dad's Key iconDad's Key.

(in Afterbirth † and Repentance) Holy Card[ | ]

When on the ground, this card looks like: HolyCard

Name ID Icon Unlock method Message Description
Holy Card 5.300.51 Holy Card Holy Card Defeat Delirium as Character The Lost iconThe Lost You feel protected Grants a one-time Collectible Holy Mantle iconHoly Mantle effect. (except in Repentance) It lasts for the current room.

(in Repentance) Uno Card[ | ]

When on the ground, this card looks like: WildCardBack

Name ID Icon Unlock method Message Description
Wild Card 5.300.80 Wild Card Wild Card Defeat Mega Satan as Character Tainted Eden iconTainted Eden Again When used, copies the effect of the most recently used Pill, Card, Rune, Soul Stone or activated item.

Runes[ | ]

Left Pointing Runes[ | ]

When on the ground, these runes look like: Rune2

Name ID Icon Unlock method Message Description
Rune of Hagalaz 5.300.32 Rune of Hagalaz Rune of Hagalaz Complete Pitch Black (challenge #1) Destruction Destroys all breakable objects in the room. Does not affect Key Blocks.
Rune of Jera 5.300.33 Rune of Jera Rune of Jera Complete High Brow (challenge #2) Abundance Clones all pickups and Chests in the room (including ShopShop pickups; the clones can then be picked up for free). Cloned chests will contain exactly the same type of items: if the original contains a pickup, so will the clone; the same is true for collectibles. Cannot clone other Jera runes and trinkets.
Rune of Ehwaz 5.300.34 Rune of Ehwaz Rune of Ehwaz Complete Head Trauma (challenge #3) Passage Creates a trapdoor leading to the next floor. Has an estimated 1/12 (8%) chance to create a trapdoor leading to a Crawl SpaceCrawl Space instead. (in Repentance) Guaranteed to create a trap door to a Crawl SpaceCrawl Space if used on floor tiles containing certain patterns. Will not create trapdoors if used on the end floor of a challenge.
Rune of Dagaz 5.300.35 Rune of Dagaz Rune of Dagaz Complete Darkness Falls (challenge #4) Purity Removes any Curses from the current floor and grants a Soul HeartSoul Heart. (This will not remove Curse of the LabyrinthCurse of the Labyrinth.)

Right Pointing Runes[ | ]

When on the ground, these runes look like: Rune1

Name ID Icon Unlock method Message Description
Rune of Ansuz 5.300.36 Rune of Ansuz Rune of Ansuz Complete The Tank (challenge #5) Vision Reveals the whole map, including the Secret RoomSecret Room and the Super Secret RoomSuper Secret Room. (This will not remove Curse of the LostCurse of the Lost.) (in Repentance) Does not reveal the Ultra Secret RoomUltra Secret Room
Rune of Perthro 5.300.37 Rune of Perthro Rune of Perthro Complete Solar System (challenge #6) Change Rerolls all item pedestals in the room (the same effect as Collectible The D6 iconThe D6).
Rune of Berkano 5.300.38 Rune of Berkano Rune of Berkano Complete Purist (challenge #20) Companionship Summons 3 friendly Blue Flies and 3 friendly Blue Spiders.
Rune of Algiz 5.300.39 Rune of Algiz Rune of Algiz Complete Cat Got Your Tongue (challenge #8) Resistance (except in Repentance) Grants a shield which lasts for 30 seconds.
(in Repentance) Grants a shield which lasts for 20 seconds.
(except in Rebirth) Blank Rune 5.300.40 Blank Rune Blank Rune (in Rebirth and Afterbirth) Complete Onan's Streak (challenge #29)
(in Afterbirth † and Repentance) Complete The Guardian (challenge #30)
??? Grants a random rune effect (except in Repentance) excluding Black Rune. Has a 25% chance to drop another Blank Rune on the ground upon use.

Other Runes[ | ]

(in Repentance) Rune Shards can be encountered only as replacements for runes that have not been unlocked. Once 6 runes of any kind (including soul stones) are available, Rune Shards cease to spawn.

Name ID Icon Unlock method Message Description
(in Afterbirth † and Repentance) Black Rune 5.300.41 Black Rune Black Rune Defeat Ultra Greedier as Character Apollyon iconApollyon Void Deals 40 damage to all enemies in the room. Consumes all pickups in the room and turns them into Blue Flies and Spiders. Consumes all pedestal items in the room and turns them into random stat upgrades.
(in Repentance) Rune Shard 5.300.55 Rune Shard Always available It still glows faintly Activates a random, weak rune effect: Algiz grants a 3 second shield, Ansuz reveals the map up to 3 rooms away (including Ultra Secret RoomUltra Secret Room), Berkano gives 1 blue fly and spider, Dagaz gives half a Soul Heart, Ehwaz makes a trapdoor, Hagalaz destroys some rocks, Jera duplicates one pickup, and Perthro rerolls one item.

(in Repentance) Soul Stones[ | ]

Soul Stones are all unlocked by beating both Boss Hush ingameHush and Boss RushBoss Rush as their respective Tainted character. They count as runes for the purposes of Collectible Clear Rune iconClear Rune and Collectible Rune Bag iconRune Bag and can spawn anywhere a rune can.

Name ID Icon Unlock method Message Description
Soul of Isaac 5.300.81 Soul of Isaac Soul of Isaac Defeat Hush and Boss RushBoss Rush as Character Tainted Isaac iconTainted Isaac Reroll... or not Rerolls the items in the room like Collectible The D6 iconThe D6, but they cycle back to their original form after one second, repeating. If more uses are stacked, an additional item per use will be cycled through.
Soul of Magdalene 5.300.82 Soul of Magdalene Soul of Magdalene Defeat Hush and Boss RushBoss Rush as Character Tainted Magdalene iconTainted Magdalene Give me your love! Surrounds Isaac with a bubbling red aura for the current room. All enemies killed drop Half Red HeartHalf Red Hearts that disappear in 2 seconds.
Soul of Cain 5.300.83 Soul of Cain Soul of Cain Defeat Hush and Boss RushBoss Rush as Character Tainted Cain iconTainted Cain Opens the unopenable Opens all doors in the room. Additionally, creates a Red RoomRed Room like the Collectible Red Key iconRed Key on all valid walls. This also destroys the mirror located in DownpourDownpour / DrossDross II.
Soul of Judas 5.300.84 Soul of Judas Soul of Judas Defeat Hush and Boss RushBoss Rush as Character Tainted Judas iconTainted Judas Right behind you Increases Isaac's speed and makes him invulnerable for 3 seconds and allows him to pass through enemies. Damages all enemies and destroys all projectiles Isaac ran through when the effect ends, and grants a temporary Damage bonus for each enemy hit.
Soul of ??? 5.300.85 Soul of ??? Soul of ??? Defeat Hush and Boss RushBoss Rush as Character Tainted ??? iconTainted ??? Chemical warfare Causes 8 poison farts that leave lingering brown creep, then plants a trail of 7 Collectible Butt Bombs iconButt Bombs in quick succession. Standing on the creep gives +1.5 Fire Rate and +1 Damage.
Soul of Eve 5.300.86 Soul of Eve Soul of Eve Defeat Hush and Boss RushBoss Rush as Character Tainted Eve iconTainted Eve Your very own murder 14 Collectible Dead Bird iconDead Bird familiars fly in and attack enemies. They leave after all enemies are dead or Isaac leaves the room.
Soul of Samson 5.300.87 Soul of Samson Soul of Samson Defeat Hush and Boss RushBoss Rush as Character Tainted Samson iconTainted Samson Slay a thousand Isaac turns berserk for 10 seconds, replacing his tears with a melee bone club and gaining +0.4 Speed, some Tears, and +3 flat Damage.
Soul of Azazel 5.300.88 Soul of Azazel Soul of Azazel Defeat Hush and Boss RushBoss Rush as Character Tainted Azazel iconTainted Azazel Demon rage! Activates Collectible Mega Blast iconMega Blast for 7.5 seconds.
Soul of Lazarus 5.300.89 Soul of Lazarus Soul of Lazarus Defeat Hush and Boss RushBoss Rush as Character Tainted Lazarus iconTainted Lazarus Life after death Isaac dies, and is immediately revived at half a Heart in the same room, with some invincibility time. The soul stone is automatically used upon taking fatal damage. Has the highest priority of all Revival items.
Soul of Eden 5.300.90 Soul of Eden Soul of Eden Defeat Hush and Boss RushBoss Rush as Character Tainted Eden iconTainted Eden Embrace chaos Uses Collectible The D6 iconThe D6 and Collectible D20 iconD20. The rerolled items use random pools, as if Collectible Chaos iconChaos were active.
Soul of the Lost 5.300.91 Soul of the Lost Soul of the Lost Defeat Hush and Boss RushBoss Rush as Character Tainted Lost iconTainted Lost Leave your body behind Isaac "dies" and turns into a ghost for the current room, with all of Character The Lost iconThe Lost's benefits and weaknesses. The Collectible Holy Mantle iconHoly Mantle effect gained from this can be stacked with multiple uses.
Soul of Lilith 5.300.92 Soul of Lilith Soul of Lilith Defeat Hush and Boss RushBoss Rush as Character Tainted Lilith iconTainted Lilith Motherhood Adds one permanent familiar from the Baby Shop pool, except Collectible Stitches iconStitches. Can give familiars that Isaac already has. Unique familiars can be received only once.
Soul of the Keeper 5.300.93 Soul of the Keeper Soul of the Keeper Defeat Hush and Boss RushBoss Rush as Character Tainted Keeper iconTainted Keeper $$$ Drops 1-25 random Coins on the ground.
Soul of Apollyon 5.300.94 Soul of Apollyon Soul of Apollyon Defeat Hush and Boss RushBoss Rush as Character Tainted Apollyon iconTainted Apollyon Bringer of calamity Spawns 15 random locusts.
Soul of the Forgotten 5.300.95 Soul of the Forgotten Soul of the Forgotten Defeat Hush and Boss RushBoss Rush as Character Tainted Forgotten iconTainted Forgotten Skeletal protector Spawns Character The Forgotten iconThe Forgotten as a temporary secondary character, controlled at the same time as Isaac. He dies with no consequences if his health run out, and disappears when Isaac leaves the room. The bone swing deals high damage, and reflects tears.
Soul of Bethany 5.300.96 Soul of Bethany Soul of Bethany Defeat Hush and Boss RushBoss Rush as Character Tainted Bethany iconTainted Bethany Friends from beyond Spawns 6 Collectible Book of Virtues iconBook of Virtues wisps with random properties.
Soul of Jacob and Esau 5.300.97 Soul of Jacob and Esau Soul of Jacob and Esau Defeat Hush and Boss RushBoss Rush as Character Tainted Jacob iconTainted Jacob Bound by blood Spawns Character Esau iconEsau as a temporary secondary character, controlled at the same time as Isaac. He dies with no consequences if his health runs out, and disappears when Isaac leaves the room. Esau has random items equal to the number of items Isaac has, each based on the pools of the items Isaac's were obtained from.

Other[ | ]

These are items other than cards and runes (and Pills) that take up the consumable slot. When on the ground, each of these items are uniquely identifiable by their respective icon. (in Repentance) These consumables cannot be replicated by either Collectible Blank Card iconBlank Card or Collectible Clear Rune iconClear Rune, and Collectible Tarot Cloth iconTarot Cloth has no effect on them, but the Collectible D1 iconD1 will always duplicate these into themselves.

Name ID Icon Unlock method Message Description
(except in Rebirth) Dice Shard 5.300.49 Dice Shard Always available D6 + D20 Upon use, invokes the effects of Collectible The D6 iconThe D6 and the Collectible D20 iconD20 at the same time, re-rolling all item pedestals and pickups in the room.
(except in Rebirth) Emergency Contact 5.300.50 Emergency Contact Always available Help from above When used, will cause two Mom's HandMom's Hands to come down and grab two random enemies, dealing damage and, if they have 40 or more HP, pinning them to the ground temporarily.
(in Repentance) Cracked Key 5.300.78 Cracked Key Red Key Open Mom's Chest in (in Repentance)HomeHome ??? Creates a room adjacent to a viable wall, like Collectible Red Key iconRed Key.

Probabilities[ | ]

Cards that spawn as random ones, i.e. with a sub-type of 0, have the following probabilities:

  • Any tarot card (1-22) - 66.66%
    • A specific tarot card - 3.03%
  • Any reverse tarot card (56-77) - 11.22%
    • A specific reverse tarot card - 0.51%
  • Any face card (23-31) - 7.74%
    • A specific face card (23-31) - 0.86%
  • Queen of Hearts (79) - 0.86% (same as a specific face card)
  • Any special card (42-54) - 3.51%
    • A specific special card - 0.27%
  • Cracked Key (78) - 0.27% (same as a specific special card)
  • Wild Card (80) - 0.27% (same as a specific special card)
  • Any rune (32-41) - 3.60%
    • A specific rune - 0.36%
  • Any soul stone (81-97) - 5.95%
    • A specific soul stone - 0.35%
  • Rune shard (55) - 0.00% (never spawns on a fully completed save file, chosen only as a replacement otherwise)

Notes[ | ]

  • (except in Repentance) The game counts runes as cards for the purposes of Collectible Blank Card iconBlank Card, and (in Afterbirth † and Repentance)Collectible Tarot Cloth iconTarot Cloth.
    • (in Repentance) Even though runes no longer count as cards as of Repentance, Collectible Little Baggy iconLittle Baggy still prevents new runes from appearing except through forced drops (such as from (in Repentance)Collectible Mom's Ring iconMom's Ring or (in Repentance)Collectible Clear Rune iconClear Rune). Runes that already existed prior to picking up Little Baggy will not be converted.
    • Collectible Starter Deck iconStarter Deck does not prevent runes/soul stones from generating, will sometimes turn pills into either, and allows holding two of them.
  • (except in Repentance) XV - The Devil card's effect does not stack with multiple uses, nor does it stack with Collectible The Book of Belial iconThe Book of Belial.
    • Collectible Blood of the Martyr iconBlood of the Martyr grants its additional 1.5x damage multiplier with XV - The Devil.
    • It also does not increase the chance of a Devil RoomDevil Room or Angel RoomAngel Room appearing when used like with the Book of Belial.
  • (except in Repentance) The damage dealt by II - The High Priestess counts as explosion damage, meaning it will not damage Isaac when possessing (except in Rebirth)Collectible Host Hat iconHost Hat or Collectible Pyromaniac iconPyromaniac.
    • The foot summoned by The High Priestess still counts as explosion damage, even though (except in Rebirth)Collectible Host Hat iconHost Hat or Collectible Pyromaniac iconPyromaniac won't prevent the damage. This means that the card can destroy rocks and open doors, including the entrance to Secret RoomSecret Rooms.
    • If there are no enemies in a room, II - The High Priestess will target Shopkeepers before targeting Isaac.
  • (except in Repentance) Using XI - Strength as Character ??? (Character) icon??? will give him a permanent Soul Heart instead of a temporary one. (in Afterbirth and Afterbirth †) When Character Keeper iconKeeper has only one Coin Heart, he can use XI - Strength to gain a second one which is also permanent. (in Repentance) Both of the mentioned characters will lose the temporary health granted by XI - Strength.
  • If Isaac uses XI - Strength card with only Soul, Black, or Bone Hearts left, and loses the non-Red Hearts while in the same room, he retains the full Red Heart Container that XI - Strength grants.
  • The heart container granted by XI - Strength cannot be used to purchase a devil deal. However, if Isaac has no other red heart containers to spent, then one granted by XI - Strength can be used this way. This also works if the devil deal costs 2 hearts, but Isaac only has 1 before activating the Strength card.
    • (in Repentance) III - The Empress? also works this way.
  • Runes will be replaced with cards if no runes are unlocked.
    • (in Repentance) However, items that normally spawn runes (e.g. Collectible Rune Bag iconRune Bag or Collectible Clear Rune iconClear Rune) can spawn Rune Shards before any runes are unlocked.
  • The Emperor, The Stars, The Hermit, The Moon and The Moon? will act as a random teleport in cases where there isn't a boss room, treasure room, shop, secret room or ultra secret room to teleport to.
  • Using IV - The Emperor on a Curse of the LabyrinthCurse of the Labyrinth floor will teleport Isaac to the second Boss RoomBoss Room.
  • III - The Empress card's effect can be stacked with multiple uses of the same card (including uses by Blank Card), and also stacks with the Collectible Whore of Babylon iconWhore of Babylon.
    • The damage bonus is the number of uses squared, e.g. +1.5 * 4 * 4 damage for using the card via a Blank Card, with Tarot Cloth and Car Battery equipped.
  • Using the Joker card in WombWomb / UteroUtero II will instantly teleport Isaac to the Devil Room or Angel Room with a trapdoor leading to SheolSheol or to the CathedralCathedral. This can be used to skip Boss Mom's Heart ingameMom's Heart and will not count as a kill.
    • (except in Rebirth) After unlocking It Lives, Devil or Angel Rooms in WombWomb / UteroUtero / Scarred WombScarred Womb II no longer contain trapdoors and instead have their normal contents.
  • Using The Joker card can allow Isaac to encounter Devil Rooms or Angel Rooms on floors they otherwise cannot appear on, such as the first floor, or (in Repentance)CorpseCorpse II.
  • While Curse of the MazeCurse of the Maze is active, 0 - The Fool, IV - The Emperor, IX - Hermit, XVII - The Stars, and XVIII - The Moon may fail and leave Isaac in a different room than intended. The Joker card still works normally.
  • Using the XIV - Temperance can, in rare cases, spawn the Blood Donation MachineBlood Donation Machine directly on Isaac, forcing him to use it once. This happens more often if Isaac is against a wall when the card is used.
  • All teleportation cards except 0 - The Fool, (in Repentance) XVII - The Stars, and (in Repentance) Joker are unavailable in Greed Mode.
  • If alternate versions of consumables have been unlocked (for example, (in Afterbirth † and Repentance) Charged KeyCharged Keys or (in Repentance) Mega ChestMega Chests), any cards that can spawn that type of consumables (for example, Ace of Spades or (in Repentance) VIII - Justice?) have a chance of being replaced with those rarer consumables.
    • Key RingKey Rings are the only exception to this.
    • Cards that are explicitly stated to spawn a type of consumable (such as VI - The Lovers spawning red hearts) will almost always drop that exact type of consumable, unless they're used in specific Secret RoomSecret Room.
  • Using a Black Rune to absorb items in Boss RushBoss Rush or Challenge RoomChallenge Rooms counts as taking the items and will cause waves of bosses or enemies to start spawning.
  • (except in Rebirth) Using the Blank Card with the ? Card teleports Isaac to the I AM ERRORI AM ERROR room of the current floor. This consumes both the Blank Card and the ? Card.
  • (in Afterbirth † and Repentance)Black Rune, unlike Collectible Void iconVoid, will grant stat ups for sacrificing active items. This makes Black Rune useful even while holding Void as any active item that would be detrimental to absorb can instead be absorbed by Black Rune.
  • (in Repentance) If Collectible Tarot Cloth iconTarot Cloth is held, and the currently held card has Tarot Cloth effects, the card will flash, indicating that it will be amplified by Tarot Cloth.
  • (in Repentance) Using any teleport cards while inside of Boss The Beast ingameThe Beast fight will simply move Isaac instantly to different spot in the same room. This also includes the Joker card.
  • (in Repentance) Leaving Trinkets in a Boss RoomBoss Room or Treasure RoomTreasure Room will transform them into a Cracked Key when on the Ascent to (in Repentance)HomeHome, if the Red Key is unlocked. This allows Isaac to unlock a Tainted Character without needing the Red Key.
  • (in Repentance) If a Black Rune is used while Isaac is holding an item above his head, it will consume the item. This allows him to immediately absorb passive items bought from Devil Rooms, Black Markets, or Shops. This also can be used to give Isaac a chance to see what an unknown item is before deciding if he wants to consume it.
  • (in Repentance) If Isaac uses the Black Rune to absorb items from a room with choice pedestals, it will only absorb one item, and the other item vanishes as if Isaac took it.
  • (in Repentance) The Black Rune can be used to absorb Collectible Knife Piece 1 iconKnife Piece 1 if Boss Mother secondphase ingameMother isn't the goal of the run. Can also be used to absorb Collectible Key Piece 1 iconKey Piece 1 or Collectible Key Piece 2 iconKey Piece 2.
  • (in Repentance) Using the Rune of Jera on a Wild Card will copy the Wild Card, allowing Isaac to infinitely copy any other consumables in the room.
  • (in Repentance) Once Boss Mother secondphase ingameMother is defeated, a unique marked skull will spawn on DepthsDepths / NecropolisNecropolis / Dank DepthsDank Depths II or XL. When destroyed, it will always drop 0 - The Fool card (Or an identified Telepills if Collectible Little Baggy iconLittle Baggy has been picked up).
  • (in Repentance) Soul of Cain's effect can open any door that Collectible Cracked Orb iconCracked Orb can, including the Strange Door and door to Mega Satan Head ingameMega Satan.
  • (in Repentance) Using Soul of The Lost and then beating a boss for a completion mark within the same room will not count as a completion mark for Character The Lost iconThe Lost. Instead, the completion mark and achievement will go to the character who used the soul stone.
  • (in Repentance) Using IV - The Emperor? in WombWomb / UteroUtero/ Scarred WombScarred Womb / CorpseCorpse I or II will teleport Isaac to a boss fight from the current boss pool.
    • Using it in SheolSheol / CathedralCathedral / Dark RoomDark Room / ChestChest / The VoidThe Void / HomeHome will teleport Isaac to a random room.
    • Using it in ?????? will teleport Isaac to a boss fight from the WombWomb boss pool.
    • Using it in an I AM ERRORI AM ERROR room will take Isaac to the last room he was in when exited, allowing him to further explore the floor.
    • It can be used to skip Boss RushBoss Rush after touching a pedestal item. After defeating the extra boss, leaving the room will lead Isaac to the regular, locked Boss Mom ingameMom boss room.
  • (in Repentance) Using IV - The Emperor? again on the same floor after defeating the boss it spawns takes Isaac back to the same cleared Boss room.
  • (in Repentance) For the purposes of tracking Collectible Heartbreak iconHeartbreak's effect on Character The Lost iconThe Lost / Character Tainted Lost iconTainted Lost, VI - The Lovers? doesn't add any hidden Broken Hearts to their healthbar, allowing them to use the card without penalty.
  • (in Repentance) Items granted by Soul of Lilith do not count as collected, and can still spawn in any pool they're in. Familiars obtained this way contribute toward transformations such as Conjoined.
  • (in Repentance) Soul of Lilith takes its familiars from the Baby Shop item pool, however when Isaac's stuff is rerolled, those familiars are rerolled in the Treasure Room item pool.
  • (in Repentance) Items granted by Soul of Lilith can be destroyed by Collectible Void iconVoid / Collectible Abyss iconAbyss for their respective bonuses right after using the soul stone while the pedestal pickup animation is playing.
  • (in Repentance) Characters granted by Souls of the Forgotten / Jacob & Esau can interact with Blood Donation MachineBlood Donation Machines, Devil BeggarDevil Beggars and Hell GameHell Games, allowing Character The Lost iconThe Lost and Character Tainted Lost iconTainted Lost to safely use them without dying, or a form of invulnerability.
  • (in Repentance) Characters granted by Souls of the Forgotten / Jacob & Esau can't be used to leave a room, thus they can't be used to negate damage from exiting a Curse RoomCurse Room.
    • They also cannot pick up items, nor can they pick up things such as pills/cards/soul stones. They can pick up hearts, however Soul of the Forgotten can only replenish its bone hearts by collecting a bone heart pickup.
  • (in Repentance) Items granted to Esau when summoned from the Soul of Jacob and Esau will remove those items from their respective pools as if the player had obtained them. This also prevents future uses of the soul stone from giving that item to Esau.
  • (in Repentance) When the Soul of Jacob and Esau is used, some items given to Esau will also apply to Isaac for the floor. This happens with Collectible Black Candle iconBlack Candle and mapping items such as Collectible The Compass iconThe Compass, for example.
    • If Esau is given Collectible PHD iconPHD, pills will remain identified for the rest of the run, even if negative pills aren't converted into positive ones.
  • (in Repentance) Items granted to the player by Collectible Eden's Blessing iconEden's Blessing are considered starting items by the effect of "XVII - The Stars?". Thus, only the first item picked up within the current run is removed.
  • (in Repentance) Before using the IX - The Hermit? card, dropping every unwanted card/pill/rune/trinket from the floor into the same room can generate heaps of extra money.
  • (in Repentance) As Character Tainted Lost iconTainted Lost, every card has a roughly 10% chance to be replaced with a Holy Card.

Unlockable Achievements[ | ]

In-game footage[ | ]

Gallery[ | ]

Trivia[ | ]

  • The appearance of the tarot cards seems to be based on the Universal Tarot of Marseille deck produced by Lo Scarabeo, most clearly seen with the card backs as well as the splash image that appears when using The Sun.
  • The runes and their names ingame are based on the Elder Futhark alphabet system and its reconstructed Proto-Germanic names. In popular culture, runes often signify that something is in some way magical.
    • (in Repentance) IX - The Hermit?'s effect was based directly on the Rune of Fehu from Antibirth. No other Antibirth rune was adapted into Repentance.
  • The Suicide King card is a nickname for the King of Hearts, referred to as such because its artwork depicts a king who seems to be sticking a sword into his own head.
  • (except in Rebirth) The Get out of Jail Free card is a reference to a card with the same name that appears in the table game Monopoly.
  • The "A Card Against Humanity" card is a reference to the card game Cards Against Humanity.
  • Ancient Recall, Era Walk, Huge Growth, and Chaos Card are all based on cards from Magic: The Gathering.
    • The Chaos Card is a reference to the card "Chaos Orb", which also instantly destroys enemies that it touches.
    • (in Afterbirth † and Repentance) The "Ancient Recall" card is a reference to the card "Ancestral Recall", which also draws three cards.
    • (in Afterbirth † and Repentance) The "Era Walk" card is a reference to the card "Time Walk", which allows players to take an extra turn.
    • (in Afterbirth † and Repentance) The "Huge Growth" card is a reference to the card "Giant Growth", which buffs creatures summoned in the game. Its message might be a reference to the card "Become Immense", a card with a similar effect to Giant Growth.
  • A NULL card with ID 0 exists, revealed by the "giveitem k0" Debug Console command. It can't be acquired or used in any way.
  • (in Afterbirth † and Repentance) Many cards were given new unique back sprites in Booster Pack #5, some originating from Antibirth.
  • (in Repentance) Soul of Cain's ability is likely a reference to Collectible Red Key iconRed Key being an unlock for Character Cain iconCain in the original Antibirth mod.
  • (in Repentance) Soul of Judas' description and ability are a reference to the Spy from Team Fortress 2.
  • (in Repentance) Soul of Samson's description is a reference to Judges: it is said that Samson killed an army of 1,000 Philistines using a donkey's jawbone.
  • (in Repentance) Soul of Eve's description is a reference to the original description Collectible Birthright iconBirthright had when taken as Character Eve iconEve in the original Antibirth mod.
    • Its effect was also probably inspired by the old original Collectible Birthright iconBirthright effect, which caused Character Eve iconEve to sometimes generate extra Collectible Dead Bird iconDead Birds upon being hit that would persist between rooms.
  • (in Repentance)III - The Empress? will display a pop up saying "The morning sun has vanquished the horrible night" a reference to Castlevania II: Simon's Quest when night turns to day.
    • This is also a reference to Collectible Whore of Babylon iconWhore of Babylon's (and by extension III - The Empress) pop up being the day to night message in said game.
  • (in Repentance) When VII - The Chariot? is activated, the statue will sometimes look like Edith, a character from Antibirth that wasn't adapted into Repentance.
  • (in Repentance) The Reverse Tarot Cards refer to tarot card readings, where a reversed card has a contrary meaning to its upright variant.
  • XVII - The Stars in actual tarot decks is just referred to as XVII - The Star.
  • (in Repentance) Rune Shards exist to counteract players who purposely avoided unlocking less useful runes. For example, prior to Repentance it was possible to purposely avoid all rune unlocks except Jera, to make exploits involving Jera and Collectible Blank Card iconBlank Card much easier. With the inclusion of the Rune Shard, avoiding rune unlocks to prioritize another is no longer possible.

Voiceovers[ | ]

Major Arcana Cards[ | ]

Tarot Card Voiceover Voiceover (Reverse)
0 - The Fool
I - The Magician
II - The High Priestess
III - The Empress
IV - The Emperor
V - The Hierophant
VI - The Lovers
VII - The Chariot
VIII - Justice
IX - The Hermit
X - Wheel of Fortune
XI - Strength
XII - The Hanged Man
XIII - Death
XIV - Temperance
XV - The Devil
XVI - The Tower
XVII - The Stars
XVIII - The Moon
XIX - The Sun
XX - Judgement
XXI - The World

Playing Cards[ | ]

Card Voiceover
2 of Clubs
2 of Diamonds
2 of Spades
2 of Hearts
Ace of Clubs
Ace of Diamonds
Ace of Spades
Ace of Hearts
Joker
Suicide King
Queen of Hearts

Runes and Soul Stones[ | ]

Rune or Soul Stone Voiceover
Hagalaz
Jera
Ehwaz
Dagaz
Ansuz
Perthro
Berkano
Algiz
Black Rune
Rune Shard
Soul of Isaac
Soul of Magdalene
Soul of Cain
Soul of Judas
Soul of ???
Soul of Eve
Soul of Samson
Soul of Azazel
Soul of Lazarus
Soul of Eden
Soul of the Lost
Soul of Lilith
Soul of the Keeper
Soul of Apollyon
Soul of the Forgotten
Soul of Bethany
Soul of Jacob and Esau

Other cards and consumables[ | ]

Consumable Voiceover
Chaos Card
Huge Growth
Ancient Recall
Era Walk
Credit Card
Rules Card
A Card Against Humanity
Get out of Jail Free Card
? Card
Dice Shard
Emergency Contact
Holy Card
Wild Card
Cracked Key

Bugs[ | ]

Bug Bug! (in Afterbirth †) Rune of HagalazRune of Hagalaz will open Secret RoomSecret Room doors in L-shaped rooms.
Bug Bug! (in Repentance) Using XVI - The Tower?XVI - The Tower? in a Boss RoomBoss Room may block all paths to the trap door, resulting in a softlock if no bombs or flight are available.
Bug Bug! (in Repentance) Using XVI - The Tower?XVI - The Tower? can also trap certain familiars over the rocks such as Collectible Lost Fly iconLost Fly until Isaac leaves the room.
Bug Bug! Any blue flies, blue spiders, (in Afterbirth † and Repentance)friendly enemies, (in Afterbirth † and Repentance)locusts, (in Afterbirth † and Repentance)orbital bones, and (in Repentance)wisps created by cards, runes, and soul stones can be multiplied when (except in Rebirth)Collectible Glowing Hourglass iconGlowing Hourglass teleports Isaac in a way that does not move him to a different room from the one he is currently in (such as by teleporting to the previous room then using it again).
Bug Bug! (in Repentance) As Character Tainted Lazarus iconTainted Lazarus, all effects of XIX - The Sun?XIX - The Sun? except bone heart conversion and sprite change will disappear when flipping.
Bug Bug! (in Repentance) Entering the Collectible Knife Piece 2 iconKnife Piece 2 area while under the effects of XIX - The Sun?XIX - The Sun? will cause a visual bug wherein Isaac will revert to his default appearance but still be capable of flight and spectral tears.
Bug Bug! (in Repentance) If an activated collectible on a pedestal is touched and then rerolled with Soul of IsaacSoul of Isaac, the alternate item(s) will also count as "already picked up": they will not drop pickups, grant health or transformations they normally would.
Bug Bug! (in Repentance) If multiple Souls of the Forgotten / Jacob & Esau are used in the same room, only 1 forgotten/pair of Jacob & Esau will be removed after leaving the room. For every room that is left, one copy of them will disappear.
Bug Bug! (in Repentance) Using a Black RuneBlack Rune in a room with exactly one pickup and one item while being near the fly limit won't suck the item.


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