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Character Tainted Cain appearance.png
Full red heartFull red heart
Table dividing line 1.png
Challenge Number
Available Rooms
Item Pool Treasure Room.png: no          Item Pool Shop.png: yes
Boss Mom.png
Justice Justice
Unlock Method

The Hoarder Use the Red Key or Cracked Key in Home as Cain

Added in Repentance

Cantripped! is challenge #43. The goal is to defeat Mom. This challenge is unlocked by unlocking Tainted Cain.

You play as Tainted Cain, but instead of crafting items from pickups, all pills and tarot cards are replaced with a unique card pickup that gives you a one room or one time (if the item is an Active Item) use of different items. Defeating bosses expands your total card carrying limit.

Strategy[edit | edit source]

  • Cain starts with 3 held item cards.
  • Each enemy has chance to drop item card after death.
    • This can be used to farm item cards with enemies which can spawn other enemies.
  • Almost all rooms drop an item card when cleared.
  • All boss rewards are changed to 15►Starter Deck Starter Deck. This increases the item cards limit by 1, and drops 3 item cards.
  • Although there are no treasure rooms and bosses do not drop standard boss items, gaining items in other ways is still possible. You won't lose those items after leaving the room. These ways include but are not limited to:
    • Buying items via Devil Deals. This is a good source of items, because during the run you will most likely get plenty of health increasing items.
    • Buying items in the Shop.
    • Using a 1 pip or 6 pip Dice Room.
  • If an item pedestal would have spawned, an item card will spawn instead. This applies to:
    • Book pedestals in the Library.
    • Items found in Chests.
    • Item spawned by other items, such as through Collectible Eden's Soul icon.pngEden's Soul.
  • Some bonuses from items will remain after leaving the room. This includes:
  • Item cards act like Pickups which can be manipulated as such (e.g. duplicated with Jera).
    • Because they act like Pickups, they can be bought in the Shop for 5 coins.
  • UsingCollectible Glowing Hour Glass icon.pngGlowing Hourglass after leaving a room will give back all items used in that room, permanently, allowing to bypass the challenge's limitations.
  • Holding onto 15►The Bible The Bible enables the player to instantly kill Mom. This can bypass the need to store several powerful items for the final fight.
  • The player can use a 15►Forget Me Now Forget Me Now in order to gain another 15►Starter Deck Starter Deck, and thus carry more items.

Unlockable achievements[edit | edit source]

  • Justice
    Justice - Complete Cantripped (challenge #43).

Trivia[edit | edit source]

  • The name of this challenge is a reference to the Magic: the Gathering term "cantrip", meaning a card that draws another card.
  • The item cards in this challenge resemble the treasure cards from The Binding of Isaac: Four Souls.

Bugs[edit | edit source]

Bug Bug! Using Glowing Hour Glass will restore any passive items used in the previous room as permanent items instead of item cards.

Gallery[edit | edit source]

MainPageChallenges.png Challenges MainPageChallenges.png

1. Pitch Black 2. High Brow 3. Head Trauma 4. Darkness Falls 5. The Tank 6. Solar System 7. Suicide King
8. Cat Got Your Tongue 9. Demo Man 10. Cursed! 11. Glass Cannon 12. When Life Gives You Lemons 13. Beans! 14. It's in the Cards
15. Slow Roll 16. Computer Savvy 17. Waka Waka 18. The Host 19. The Family Man 20. Purist
21. XXXXXXXXL 22. SPEED! 23. Blue Bomber 24. PAY TO PLAY 25. Have a Heart 26. I RULE! 27. BRAINS!
28. PRIDE DAY! 29. Onan's Streak 30. The Guardian
Afterbirth †
31. Backasswards 32. Aprils Fool 33. Pokey Mans 34. Ultra Hard 35. Pong
36. Scat Man 37. Bloody Mary 38. Baptism by Fire 39. Isaac's Awakening 40. Seeing Double 41. Pica Run 42. Hot Potato
43. Cantripped! 44. Red Redemption 45. DELETE THIS
The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth
Achievements Achievements Attributes Attributes Bosses Bosses TarotCard.png Cards and Runes Challenges Challenges Chapters Chapters
Characters Characters MainPageBabies.png Co-op Items Items Item pools Item pools Monsters Monsters Objects Objects
Pickups Pickups Pills Pills Rooms Rooms Seeds Seeds Transformations Transformations Trinkets Trinkets