Binding of Isaac: Rebirth Wiki

Disambig.png This article is about the item. For the trinket, see Cancer (Trinket).

Cancer is a passive item.


  • Grants three Soul Heart Soul Hearts.
  • After taking damage, grants The Wafer The Wafer effect of damage reduction for the current room.

In-game Footage[]


PC 9TPQ J2AM (Treasure Room adjacent to spawn)

PC Q8GC 7GQQ (Treasure Room, second floor)

PC G4AZ K1EK (Treasure Room adjacent to spawn)

3DS F9GW K1Q0 (Treasure Room adjacent to spawn)

Switch Greedier mode only WLHZ P736 (First Golden Treasure Room)

Xbox L133 W88G (first golden treasure room)