Binding of Isaac: Rebirth Wiki
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Not to be confused with Cain's EyeCain's Eye, (except in Rebirth)Collectible Evil Eye iconEvil Eye, or (in Afterbirth † and Repentance)Collectible Glaucoma iconGlaucoma.

Cain's Other Eye is an unlockable passive item.

Effects[ | ]

  • (except in Repentance) Spawns a familiar that floats slowly around the room in a zig-zag pattern similar to Collectible The Peeper iconThe Peeper and shoots normal tears in the same direction as Isaac.
    • (in Rebirth) Each tear deals 3.5 damage.
    • (in Afterbirth and Afterbirth †) Each tear deals Isaac's damage.
  • (in Repentance) Spawns a familiar that follows Isaac and copies all of his tear modifiers/stats, with a 25% damage reduction. It fires randomly in the cardinal directions.

Notes[ | ]

  • (except in Repentance) Unlike Collectible The Peeper iconThe Peeper, Cain's Other Eye does no contact damage.
  • (in Repentance) This item is functionally identical to Collectible Incubus iconIncubus, except it fires in a random direction. For a list of synergies and interactions, visit that page.
  • (in Repentance) Familiars that follow behind Isaac have a certain priority in how close their position is to him over other familiars, with Cain's Other Eye having 5th priority.

Interactions[ | ]

  • (in Repentance)Collectible Epic Fetus iconEpic Fetus: Cain's other eye gains a crosshair and rocket similar to Isaac's but smaller. Caution is required, as the crosshair is erratic and will constantly shake, possibly making the rocket hit Isaac.
  • (in Repentance)Collectible Eye of the Occult iconEye of the Occult: The familiar's tears travel a very short distance in their original direction and can be controlled afterwards.
  • (in Repentance)Collectible King Baby iconKing Baby: Cain's Other Eye will attempt to fire directly at enemies but only when they are on the same side as the random direction it is firing in.

In-game Footage[ | ]

Trivia[ | ]

  • This item is implied to be the damaged eye of Character Cain iconCain beneath his eyepatch.
  • Rather than deciding a random input when a tear is fired, the familiar will rapidly switch the direction it's facing at all times.


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