Binding of Isaac: Rebirth Wiki
Binding of Isaac: Rebirth Wiki

Added in Afterbirth †
Disambig-dark.png This article is about Brittle Bones, similar in appearance to Compound Fracture.

Brittle Bones is an unlockable passive item added in The Binding of Isaac: Afterbirth †.


  • Grants 6 empty Bone Hearts.
  • Removes all Red Heart containers. Does not remove existing Bone Hearts, but does empty them.
  • Upon losing a Bone Heart, including ones acquired from other sources, Isaac fires a ring of 8 bones that split into more bones and permanently gains a +0.5 tears up.
    • Each bone does twice Isaac's damage plus a flat 22 damage; split bones do half this amount.


  • Picking this item up as The Lost The Lost or Keeper Keeper will give a one-time +0.5 tears up (Added in Repentance +0.4). This bonus is retained even if the item is later lost or rerolled.
    • Keeper will also gain 24 Blue Flies.
  • Added in Repentance The tears up bonuses gained through this item will persist in the escape sequence of Mines Mines II.
  • Added in Repentance Losing Bone Hearts through a Devil Deal will not give the tears up effect.
  • If Brittle Bones is removed (such as with Tainted Isaac Tainted Isaac), existing tear upgrades will not be removed.
    • Added in Repentance15►Genesis Genesis will remove the tear upgrades upon use.


  • 15►Empty Vessel Empty Vessel: The empty Bone Hearts will trigger Empty Vessel's effects.

In-game Footage[]


  • Brittle Bones has been added in Booster Pack #5, after the initial release of the DLC.
  • "Everything hurts" may be a reference to Melting from Nuclear Throne.



Bug Bug! For some players, when picking up Brittle Bones as the Keeper, he will instantly die and spawn lots of Blue flies.

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