Binding of Isaac: Rebirth Wiki

Added in Afterbirth †
Disambig-dark.png This article is about Brittle Bones, similar in appearance to Compound Fracture.

Brittle Bones is an unlockable passive item added in The Binding of Isaac: Afterbirth † (Booster Pack #5).


  • Grants 6 empty Bone Heart Bone Hearts.
  • Removes all Red Heart containers. Does not remove existing Bone Hearts, but does empty them.
  • Upon losing a Bone Heart, including ones acquired from other sources, Isaac fires a ring of 8 bones that split into more bones and gains a permanent +0.4 fire rate, which can break the tear fire rate cap.
    • Each bone does twice Isaac's damage plus a flat 22 damage; split bones do half this amount.


  • Picking this item up as The Lost The Lost or Keeper Keeper will give a one-time +0.5 tears up (Added in Repentance +0.4 fire rate). This bonus is retained even if the item is later lost or rerolled.
  • Added in Repentance The tears up bonuses gained through this item will persist in the escape sequence of Mines Mines II.
  • Added in Repentance Losing Bone Hearts through a Devil Deal will not give the tears up effect.
  • If Brittle Bones is removed (such as with Tainted Isaac Tainted Isaac), existing tear upgrades will not be removed.


  • Empty Vessel Empty Vessel: The empty Bone Hearts will trigger Empty Vessel's effects.
  • Added in Repentance ??? ???: Brittle Bones will not get rid of ???'s Soul Hearts, and considering he can't fill the Bone Hearts, he can break them, giving him lots of tears ups without any downsides. However, having more than 8 Soul Hearts will get rid of the other Soul Hearts to put in the Bone Hearts.


  • Added in RepentanceGenesis Genesis: Removes the tear upgrades upon use.

In-game Footage[]


  • "Everything hurts" may be a reference to an achievement of the same name from the video game Nuclear Throne.