Binding of Isaac: Rebirth Wiki
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A breaking run is a community term referring to a scenario where Isaac can create an infinite number of items to get whatever combination of items he wants, making the rest of the run trivial to beat.

Elements of Breaking Runs[ | ]

Breaking runs work by manipulating items to appear from regular pickups in a renewable way, whether they be rerolling pickups, duplicating chests, or endlessly restocking items. Many of the items that enable this can be found in Arcades, Shops, and Super Secret Rooms; anything that lets Isaac make better use of these items and rooms makes it easier for the circumstances required for a breaking run to come together.

Method 1: Blank Card/Clear Rune + Jera + Infinite Charges[ | ]

This can endlessly duplicate Locked Chests with items in them to create an endless amount of items.

(except in Repentance) With Blank Card + Jera (in Repentance) Clear Rune + Jera, Lil' Batteries can be duplicated endlessly, and if a chest on the floor has an item in it, all chests duplicated from it will also have items. From this, chests can be duplicated endlessly, creating infinite items. Note that keys will also have to be duplicated to open the chests if they're Locked/Eternal Chests, or bombs if they're Bomb Chests.

(except in Repentance) Method 2: IV Bag + Restock[ | ]

One of the simplest methods of breaking a run, it allows Isaac to buy as many items as he wants from the Shop. This is not possible in Greed mode because Blood Donation Machines cannot spawn in Greed mode, and Character The Lost iconThe Lost cannot use this because IV Bag ignores Collectible Holy Mantle iconHoly Mantle and will kill him.

  • (in Repentance) This method is no longer possible, due to restock increasing the price of hearts each time they're purchased.
  • Elements:
    • Collectible IV Bag iconIV Bag, obtained from Blood Donation Machines (in Afterbirth † and Repentance) or Locked Chests.
    • (except in Rebirth)Collectible Restock iconRestock, bought from the Shop.

On average, Collectible IV Bag iconIV Bag makes more cash from Red Hearts than it costs to purchase them, and with Restock he can buy endless Red Hearts to make an infinite amount of money. (except in Rebirth) Collectible Restock iconRestock also makes the items in the Shop restock when purchased, meaning he can also buy out every item from the shop until Collectible Chaos iconChaos shows up, at which point he can empty every item pool in the game.

Method 3: Pickup Generation on Hit + Damage Source + Cracked Dice[ | ]

This allows Isaac to generate endless pickups, which can then be rerolled into hearts to continue generating more pickups and chests to generate endless items. This method is unavailable to Character The Lost iconThe Lost, as it requires taking damage to work.

(except in Rebirth)Cracked DiceCracked Dice has a 25% chance to reroll every pickup in the room, and can be fueled by items like Collectible Piggy Bank iconPiggy Bank or Collectible IV Bag iconIV Bag that generate pickups on hit. Once enough pickups are accumulated, the room can completely refill Isaac’s health on each reroll as well as spawn many chests, creating a renewable cycle of item and health generation.

(except in Repentance) Method 4: D20 + Infinite Charges[ | ]

Similar to the previous method, this can create an endless amount of chests, but relies on having active item charges to reroll pickups instead of taking damage. This was the original breaking method back in The Binding of Isaac: Wrath of the Lamb.

After opening a chest, the D20 can reroll all the pickups created by the chest as well as the empty chest itself (unless it had an item) for the chance at more chests. With a way to endlessly recharge the D20, these pickups can be continually rerolled into chests and opened to eventually create an endless supply of coins to buy Lil' Batteries (if using Restock) and chests for items.

(in Repentance) Method 5: Modeling ClayModeling Clay + Cards/Pills[ | ]

Because Modeling Clay can cycle between item effects by leaving and re-entering rooms constantly, it can be used to constantly reroll cards, then use those cards to spawn items in Secret Rooms that constantly cycle between items due to Collectible Glitched Crown iconGlitched Crown, allowing many powerful and game-breaking items to be acquired (such as Collectible Clear Rune iconClear Rune, Collectible Rune Bag iconRune Bag, Collectible R Key iconR Key, Collectible Spindown Dice iconSpindown Dice, Collectible D infinity iconD infinity, Collectible Echo Chamber iconEcho Chamber, and Collectible Death Certificate iconDeath Certificate).

To start, gather all the cards/pills on the floor and drop them outside the Shop, and then constantly leave and re-enter the Shop. When Modeling Clay mimics Collectible Little Baggy iconLittle Baggy and Collectible Starter Deck iconStarter Deck, it will transform the cards/pills into new ones. This can be done indefinitely until they become cards you want, at which point you’ll drop them in a Secret Room.

Once you have all the cards you want in the Secret Room, leave and re-enter it until Modeling Clay mimics Collectible Echo Chamber iconEcho Chamber. Once it does, use all the cards you left in the room, starting with ones that spawn stage elements that can spawn items (such as machines, beggars, and chests), then moving to ones that spawn resources, and ending with ones that have neutral effects.

Finally, once you’ve used all the cards and all the item-spawning stage elements have been made, leave and re-enter the Secret Room until Modeling Clay mimics Collectible Glitched Crown iconGlitched Crown. Once it does, you can open all the chests and play the machines/beggars, and any items they spawn will also cycle between 4 extra Secret Room items to choose from.

If you’re not able to get enough cards to start a breaking run on the current floor, don’t worry; Echo Chamber will remember the cards you used on earlier floors, allowing you to resume where you left off on later floors.

Cards you’re looking for include ones that:

Unique Advantages[ | ]

Breaking runs are able to reroll through entire item pools, allowing them to get combinations of any items they want. Aside from making runs easy, this carries with it some unique advantages.

  • (in Afterbirth † and Repentance)Collectible Mama Mega! iconMama Mega! lets Isaac open the doors to Boss Rush or ??? without having to meet their time limits. It can be obtained from Shops or Bomb Bums (which can be spawned by using XX - Judgement continuously), meaning breaking runs can complete Boss Rush, Hush, and/or Delirium with a run that’s as powerful as they want it to be.
  • (except in Rebirth) Picking up multiple copies of Collectible Eden's Blessing iconEden's Blessing makes it so Isaac starts with that many random items at the start of the next run, up to a maximum of ten; if ten or more Eden’s Blessings were picked up, all leftover items to be given will instead go to the next run, and so on and so forth until there are no more random items to be given. (in Afterbirth † and Repentance) With the use of Collectible Glowing Hourglass iconGlowing Hourglass, Collectible Crooked Penny iconCrooked Penny, Collectible Schoolbag iconSchoolbag, and an endless supply of Little Batteries, an indefinite amount of Eden’s Blessings can be picked up, and Isaac can start every run thereon with ten more items.
  • (in Repentance) Collectible R Key iconR Key lets Isaac go back to the start of a new run while retaining all his items and unlocks. Breaking runs create R Keys in a Secret Room, hold them in a Collectible Moving Box iconMoving Box, and use them at the end of a path to go after achievements on multiple paths with the same build.
  • (in Afterbirth † and Repentance)Collectible Clicker iconClicker transforms Isaac into another unlocked character, and completion marks earned will be for the character transformed into. This means once a breaking run has Clicker, it can earn completion marks for any character. (in Repentance) Note that normal characters cannot transform into tainted characters, or vice versa.
    • (in Repentance) The prevention from transforming between tainted and normal characters can be circumvented if you are playing as a tainted character. If you are doing, for example, the Tainted Cain method, if you craft Collectible Ankh iconAnkh, Collectible Lazarus' Rags iconLazarus' Rags, or Collectible Judas' Shadow iconJudas' Shadow, if you die and revive, you will be resurrected as a non tainted character, and using the clicker will swap between non tainted characters. Note that there is no item to turn you into a tainted character as a non tainted one.

Notes[ | ]

  • All breaking runs will eventually lead into the Treasure Room item pool when their original item pools are emptied, then eventually create only Collectible Breakfast iconBreakfast once the Treasure Room is emptied of items. Breakfast is a sign that a breaking run has become as powerful as it can be (unless Chaos is involved).
  • (except in Repentance) Collectible 9 Volt icon9 Volt should be avoided if Collectible Sharp Plug iconSharp Plug is being used to endlessly recharge an active item; 9 Volt prevents an active item from reaching 0 charges, which is required for Sharp Plug to be used.


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