Binding of Isaac: Rebirth Wiki
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Brains move around the room slowly, leaving a trail of Creep that does one full heart of damage to Isaac. They are relatively weak on their own, but can quickly corner Isaac when fought in groups. Brains can also be spawned by Oobs.

Variants

Poison Mind

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Poison Minds behave like regular Brains, but crawl diagonally and leave a trail of green creep. Poison Minds can also be spawned by Oobs.

MemBrain

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The MemBrain is a much larger Brain that slowly moves around the room and occasionally hops to fire blood shots in 8 directions. It has a large amount of health, and will split into two Brains upon death.

Trivia

  • MemBrains have,along with Dingas and Mama Guts,the second-highest base health of all the non-bosses enemies, second to Oobs.

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