Brain

From Binding of Isaac: Rebirth Wiki
Jump to: navigation, search
Brain
Entity image

Base HPStage HP
20
0
Table dividing line 1.png
Entity ID
32.0
Table dividing line 2.png
Found In
Stage Depths icon.pngStage Necropolis icon.pngStage Dank Depths icon.png
Stage Womb icon.pngStage Utero icon.pngStage Scarred Womb icon.png
Stage Corpse icon.png
Challenge Room Icon.png

Brains move around the room slowly, leaving a trail of Red Creep that does half a heart of damage to the player, though they do 1 heart worth of contact damage. They are relatively weak on their own, but can quickly corner Isaac when fought in groups. Two of them are spawned from MemBrains upon death. Brains can also be spawned by Oobs.

Variants[edit | edit source]

Pon[edit | edit source]

Pon
Entity image

Base HPStage HP
20
0
Table dividing line 1.png
Entity ID
840.0
Table dividing line 2.png
Found In
Stage Depths icon.pngStage Dank Depths icon.png
Stage Mines icon.png
Stage Mausoleum icon.png
Added in Repentance

Pons are enemies which spawn when a Loose Knight is killed, and hop around leaving Red Creep wherever they land. Killing them will kill their corresponding Brainless Knight.

Poison Mind[edit | edit source]

Poison   Mind
Entity image

Base HPStage HP
20
0
Table dividing line 1.png
Entity ID
301.0
Table dividing line 2.png
Found In
Stage Necropolis icon.png
Stage Womb icon.pngStage Utero icon.pngStage Scarred Womb icon.png
Chance to replace Brains
Table dividing line 3.png
Unlock Method
The gate is open! Defeat The Lamb
Added in Afterbirth †

Poison Minds behave like regular Brains, but they crawl diagonally and leave a trail of Green Creep.

Added in Repentance Poison Minds float, passing over obstacles, and explode when killed.

Black Globin's Head[edit | edit source]

Black   Globin's   Head
Entity image

Base HPStage HP
20
0
Table dividing line 1.png
Entity ID
279.0
Table dividing line 2.png
Found In
Stage Cellar icon.png
Stage Depths icon.pngStage Necropolis icon.pngStage Dank Depths icon.png
Stage Sheol icon.png
Challenge Room Icon.pngCurse Room Icon.pngSecret Room Icon.pngSuper Secret Room Icon.png
Spawned after killing a Black Globin.
Added in Afterbirth

Black Globin's Heads behave like Brains, but they target Isaac directly, chasing him.

Notes[edit | edit source]

  • Added in Afterbirth † If Poison Minds aren't unlocked yet, they are replaced by Brains.
  • Added in Afterbirth † Black Globin's Heads can spawn in Super Secret Rooms.

Trivia[edit | edit source]

  • Added in Repentance The name of Pon is likely in reference to the Pons region of the brain, a part of the brainstem associated with respiration and other autonomic functions.


The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth
Achievements Achievements Attributes Attributes Bosses Bosses TarotCard.png Cards and Runes Challenges Challenges Chapters Chapters
Characters Characters MainPageBabies.png Co-op Items Items Item pools Item pools Monsters Monsters Objects Objects
Pickups Pickups Pills Pills Rooms Rooms Seeds Seeds Transformations Transformations Trinkets Trinkets