Brains slide around the room erratically in the cardinal directions, leaving a trail of Red Creep, they deal a whole heart of contact damage. When Isaac is within line of sight they will charge in his direction until they collide with an obstacle or another enemy similar to Knights.
Poison Minds behave like regular Brains, but they slide diagonally and leave a trail of Green Creep.
Poison Minds float, passing over obstacles, and explode when killed.
Black Globin's Head
Black Globin's Heads behave like Brains, but they target Isaac directly, chasing him.
They can spawn with a paired Brainless Knight in which killing them is required to kill their corresponding Brainless Knight. A Pon and a Brainless Knight pair will always spawn when Loose Knight is killed.
- If Poison Minds aren't unlocked yet, they are replaced by Brains.
- Black Globin's Heads can spawn in Super Secret Rooms.
- The name of Pon is likely in reference to the Pons region of the brain, a part of the brainstem associated with respiration and other autonomic functions.
|The Binding of Isaac: Rebirth|
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