Not to be confused with 
Moving Box or 
Pandora's Box.
Box is a passive item.
Effects
Notes
- The Box's pickups can be of any variety:
- Coin: Nickel, Dime, Lucky, Sticky Nickel, Golden
- Bomb: 1+1 Bombs, Troll Bomb, Golden Bomb
- Heart: Double Heart, Half-Heart, Soul, Half-Soul, Black, Eternal, Gold, Bone, Rotten
- Key: Golden, Charged Key
- Card: Reversed Cards
- Rune: Soul Stones
- Pill: Horse or Golden pills
- Trinket: Golden Trinket
Box's quality is treated as 1 for the purposes of Bag of Crafting.
Box's quality is treated as 1 for the purposes of 
In-game Footage
Trivia
- While walking to the right, Isaac's name can be seen written on the box.
- This item was the final item added in Wrath of the Lamb.
 The Binding of Isaac: Rebirth
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