Box is a passive item.
- The Box's pickups can be of any variety:
- Coin: Nickel, Dime, Lucky, Sticky Nickel, Golden
- Bomb: 1+1 Bombs, Troll Bomb, Golden Bomb
- Heart: Double Heart, Half-Heart, Soul, Half-Soul, Black, Eternal, Gold, Bone, Rotten
- Key: , Golden, Charged Key
- Card: Reversed Cards
- Rune: Soul Stones
- Pill: Horse or Golden pills
- Trinket: Golden Trinket
- Dropping this item as Tainted Isaac and picking it back up will not spawn consumables again.
- While walking to the right, Isaac's name can be seen written on the box.
- This item was the final item added in Wrath of the Lamb.
|The Binding of Isaac: Rebirth|
|Achievements||Attributes||Bosses||Cards and Runes||Challenges||Chapters|