Binding of Isaac: Rebirth Wiki
Binding of Isaac: Rebirth Wiki

Book of Shadows is an activated item.


  • Creates a protective shield, nullifying all types of damage for 10 seconds.
  • Added in Afterbirth † This item belongs to the Bookworm set. Collecting three items from this set will transform Isaac into Bookworm.



  • Orbitals such as 15►Cube of Meat Cube of Meat are highly effective with Book of Shadows, as Isaac can run into enemies with an active shield to deal massive amounts of damage.
  • Removed in Repentance15►Razor Blade Razor Blade: Can be used at no cost while the Book of Shadows shield is present, allowing damage to be significantly increased for the room.
  • Added in Repentance15►4.5 Volt 4.5 Volt: With sufficient damage (18+ DPS) the Book of Shadows shield can be kept active indefinitely. If combined with 15►9 Volt 9 Volt, Isaac only needs 12 DPS to achieve invulnerability.


  • Added in Repentance15►Blood Oath Blood Oath: If the book is used just before the knife stabs Isaac, he will not lose any health, nor gain any stat upgrades associated with the item. The extra health saved may be useful on floors with Arcades or for other uses as stated above. An incredibly useful item to find in the Bloody Mary challenge.

In-game Footage[]


  • The Book of Shadows is a reference to the infamous Book of Shadows, a book of religious texts and instructions for magical rituals found within the Neopagan religion of Wicca.



PC 4AP4 J07H (First floor Treasure Room, north of spawn; Curse of the Unknown)

PS4 VZFS Z60W (First floor Treasure Room)

Vita CBWE 162X (Treasure Room adjacent to spawn)

3DS TRKL JDCG (First floor Treasure Room)

Switch Normal mode only 7ENY AQRB (First Floor Treasure Room)

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