Binding of Isaac: Rebirth Wiki
Binding of Isaac: Rebirth Wiki

Book of Secrets is an unlockable activated item.


  • Randomly adds the effect of 15►Treasure Map Treasure Map, 15►The Compass The Compass, or 15►Blue Map Blue Map for the duration of the current floor.
    • Added in Repentance If all effects are active, 15►X-Ray Vision X-Ray Vision is provided for the floor instead.
    • Added in Repentance If Curse of the Lost or an Amnesia pill is active on a floor, X-Ray Vision effect is provided immediately.
  • Repeated activations will continue to add the other items' effects.
    • Removed in Repentance The chosen effect on activation may be one that Isaac already has - effectively doing nothing.
    • Added in Repentance Book of Secrets cannot give mapping effects that Isaac already has (whether from a previous activation or through possessing the equivalent item).
  • Added in Afterbirth † This item belongs to the Bookworm set. Collecting three items from this set will transform Isaac into Bookworm.


  • Added in Repentance 15►Book of Virtues Book of Virtues: Spawns wisps in the middle ring, looking like tiny spinning question marks. The wisps invoke the effect of 15►Cracked Orb Cracked Orb when destroyed.
  • Added in Repentance15►The Mind The Mind: Immediately gives the X-Ray Vision effect for the floor upon use.




  • This item may be a reference to an Apocryphon, or 'secret book'. This term is used to refer to early Christian writings that were written to teach 'secret knowledge' that wasn't allowed to be publicly taught.
  • Removed in Repentance Prior to Repentance, this item's description was "??????"


PC ANVY YAPC (First floor Library)

PS4 2YVW FZ34 (Treasure Room adjacent to spawn)

Vita FHQG 1L9Y (First floor Treasure Room)