Binding of Isaac: Rebirth Wiki

Book of Revelations is an unlockable activated item.


  • On use, gives one Soul Heart Soul Heart.
  • Increases chance for a Devil Room Devil Room or Angel Room Angel Room door to open by 17.5% (Removed in Afterbirth35%) if held while killing the final boss of the floor.
  • If the Book of Revelations is used at least once on a floor, a Harbinger will Added in Afterbirth / Removed in Repentance sometimes/Added in Repentance always replace the current floor's boss if possible.
  • Added in Afterbirth † This item belongs to the Bookworm set. Collecting three items from this set will transform Isaac into Bookworm.


The Harbingers capable of appearing, and the floors they appear on, are as follows:

  1. Famine Famine in Chapter 1
  2. Pestilence Pestilence in Chapter 2
  3. War War in Chapter 3, floor 1
  4. Death Death or Conquest Conquest (if unlocked) in Chapter 4, floor 1
  5. The Headless Horseman The Headless Horseman on any floor in Chapters 1-4
  • Set bosses ( Mom Mom, Isaac Isaac, The Lamb The Lamb, etc.) are unaffected by Book of Revelations.
  • Only the first boss of a floor affected by Curse of the Labyrinth.png Curse of the Labyrinth is affected.
  • Book of Revelations won't replace the boss on double-sized Boss Room Boss Rooms, like Double Trouble rooms or if the boss is Mr. Fred Mr. Fred.
    • Furthermore, if the Book of Revelations is used on the first floor of a Chapter with a Double Trouble room no Harbinger will spawn on the second floor, even if Book of Revelations is used again. If finding a Harbinger is desired, Isaac should wait until seeing the shape of the Boss Room before using it.
  • Keeping Book of Revelations until Chapter 4 is one of the methods to unlock achievements related to Super Meat Boy and Super Bandage Girl, explained in detail here.
  • This item can replace the Boss even after Isaac initiates a battle with a normal boss and then teleports out before the fight is completed.
  • Added in Afterbirth † / Removed in Repentance This item can (Added in Repentance will) replace The Bloat The Bloat with a Harbinger in Aprils Fool (challenge #32).
  • Added in Repentance Bosses in Downpour Downpour / Mines Mines / Mausoleum Mausoleum and their variants cannot be replaced with Harbingers.
  • Added in Repentance This item will replace Mother Mother with Death or Conquest during Red Redemption (challenge #44).


  • Added in RepentanceBook of Virtues Book of Virtues: Creates wisps in the inner ring, resembling tiny crosses that do not fire tears. The wisps create Harbingers that spawn Locusts (the same ones that 7 Seals 7 Seals creates) for the current room when destroyed.


In-game Footage[]



  • The Book of Revelation (note the lack of an "s") is the final book of The Bible. It depicts the apocalypse through a vision shown to John of Patmos and includes the Four Horsemen and themes of Hell, Satan, and The Lamb. This explains why using it causes the next boss to be a Harbinger, as well as why it increases the chances of a Devil Room Devil Room / Angel Room Angel Room to appear.


PC Normal mode only 3C6Z 880R (Treasure Room Treasure Room adjacent to spawn)

PC 9867 22FF (Treasure Room Treasure Room adjacent to spawn)

PC 42ZY EYNS (Treasure Room Treasure Room adjacent to spawn)

PC 6A7C BBKN (Treasure Room Treasure Room adjacent to spawn)

PS4 BQ7G DLKQ (Treasure Room Treasure Room adjacent to spawn)

PS4 G98Z MNSS (Treasure Room Treasure Room adjacent to spawn)

Vita RKV8 O883

3DS GKM3 XJJ0 (Treasure Room Treasure Room adjacent to spawn)

Switch V10Q 3WX1 (Starting item as Eden Eden)

Switch DM91 QYEQ (First Treasure Room Treasure Room)