Bob's Brain

Item Icon
Pickup Quote	"Explosive thoughts"
Entity ID	5.100.273
Item Pool	Golden Chest Baby Shop Rotten Beggar Treasure Room Golden Chest Treasure Room
Quality	1
Item Tags
Collection Grid	(page 3, column 8, row 7) (page 3, column 8, row 2) (page 3, column 9, row 2)

Bob's Brain is a passive item.

Effects

• Spawns a familiar that can be fired towards enemies as a projectile.
  • Bob's Brain is fired directly from where Isaac is standing.
  • Bob's Brain is fired directly from where it is located in the chain of familiars behind Isaac, making aiming it slightly more difficult.
• If it hits an enemy, it deals 3.5 damage and explodes, further damaging and poisoning monsters.
  • The explosion deals 60 damage.
  • The explosion deals 100 damage.
  • The explosion ignores armor.
  • The poison deals double Isaac's damage over time.
• The explosion can hurt Isaac, dealing a full heart of damage.
  • This can make picking up the item a risky choice, as Bob's Brain will always fire, regardless of whether or not Isaac will be caught in the explosion.
• Once it explodes, it takes a few seconds to re-appear.
• This item belongs to the Bob set. Collecting three items from this set will transform Isaac into Bob.

Notes

• Bob's Brain is affected by most bomb modifiers.
• Bob's Brain only explodes when hitting an enemy, and does not explode upon hitting a fire, poop, or wall. It can destroy poops and fires like normal shots, however.
• Bob's Brain never launches immediately upon entering a room unless a tear-firing key is released and pressed again, or until several seconds have passed.
• It is possible to get multiple Bob's Brains to spawn on the same floor by finding one in a Locked Chest and not taking it
  • Only one copy of the brains will be active at a given time, with another one firing immediately after the first has exploded or starts to return from a miss.
  • Multiple copies of Bob's Brain will float in the same spot in the familiar line.
  • Each copy takes up their spot on the familiar line, but only the first one launches out. Respawning brains may end up stacking on top of each other.

Synergies

• BFFS!: The impact damage is increased to 7 and the explosion deals an additional 25 damage.
• Mr. Mega: The explosion deals an additional 85 damage.
• Sad Bombs: Bob's Brain will fire tears upon exploding.
• Brimstone Bombs: Brimstone beams will shoot out upon exploding.

Interactions

• Bobby-Bomb: No effect.
• Bomber Boy: Explosion damage is halved, with no additional explosions.
• Duct Tape: Bob's Brain stays in place relative to Isaac until it is fired.
• E. Coli/ Flush!: Bob's Brain will explode upon hitting an enemy that has been turned into poop.

Trivia

• Three copies of this item are used in BRAINS! (challenge #27).
• In a Twitter AMA, Edmund McMillen mentioned that Bob's Brain is his favorite item from The Binding of Isaac.

The Binding of Isaac: Rebirth
Achievements	Attributes	Bosses	Cards and Runes	Challenges	Chapters
Characters	Co-op	Items	Item pools	Monsters	Objects
Pickups	Pills	Rooms	Seeds	Transformations	Trinkets