Bob's Brain

"Explosive thoughts"
Entity ID	5.100.273
Item Pool	Golden Chest Baby Shop Rotten Beggar Treasure Room Golden Chest Treasure Room
Collection Grid	(page 3, column 8, row 2) (page 3, column 8, row 7) (page 3, column 9, row 2)

Bob's Brain is a passive item.

Effects

• Spawns a familiar that can be fired towards enemies as a projectile.
  • Bob's Brain is fired directly from where Isaac is standing.
  • Bob's Brain is fired directly from where it is located in the chain of familiars behind Isaac, making aiming it slightly more difficult.
• If it hits an enemy, it deals 3.5 damage and explodes, further damaging and poisoning monsters.
  • The explosion deals 60 damage.
  • The explosion deals 100 damage.
  • The explosion ignores armor.
  • The poison deals double Isaac's damage over time.
• The explosion can hurt Isaac, dealing a full heart of damage.
  • This can make picking up the item a risky choice, as Bob's Brain will always fire, regardless of whether or not Isaac will be caught in the explosion.
• Once it explodes, it takes a few seconds to re-appear.
• This item belongs to the Bob set. Collecting three items from this set will transform Isaac into Bob.

Notes

• Bob's Brain is affected by most bomb modifiers.
• Bob's Brain only explodes when hitting an enemy, and does not explode upon hitting a fire, poop, or wall. It can destroy poops and fires like normal shots, however.
• Bob's Brain never launches immediately upon entering a room unless a tear-firing key is released and pressed again, or until several seconds have passed.
• It is possible to get multiple Bob's Brains to spawn on the same floor by finding one in a Locked Chest and not taking it
  • Only one copy of the brains will be active at a given time, with another one firing immediately after the first has exploded or starts to return from a miss.
  • Multiple copies of Bob's Brain will float in the same spot in the familiar line.
  • Each copy takes up their spot on the familiar line, but only the first one launches out. Respawning brains may end up stacking on top of each other.

Synergies

• BFFS!: The impact damage is increased to 7 and the explosion deals an additional 25 damage.
• Mr. Mega: The explosion deals an additional 85 damage.
• Sad Bombs: Bob's Brain will fire tears upon exploding.
• Brimstone Bombs: Brimstone beams will shoot out upon exploding.

Interactions

• Bobby-Bomb: No effect.
• Bomber Boy: Explosion damage is halved, with no additional explosions.
• Duct Tape: Bob's Brain stays in place relative to Isaac until it is fired.
• E Coli/ Flush!: Bob's Brain will explode upon hitting an enemy that has been turned into poop.

Trivia

• Three copies of this item are used in BRAINS! (challenge #27).
• In a Twitter AMA, Edmund McMillen mentioned that Bob's Brain is his favorite item from The Binding of Isaac.