Bloody Mary

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Bloody   Mary
Character Bethany appearance.png
Full red heartFull red heartFull red heartFull red heart
Table dividing line 1.png
Challenge Number
Available Rooms
Item Pool Treasure Room.png: no          Item Pool Shop.png: yes
Boss Satan.png
Unlock Method

Bloody Mary Defeat Mom's Heart/It Lives on hard mode as Lazarus Lazarus, without dying, defeat Mom's Heart 11 times and unlock 15►Blood Bag Blood Bag

Added in Repentance

Bloody Mary is challenge #37. The goal is to defeat Satan. This challenge is unlocked by unlocking Bethany, 15►Blood Bag Blood Bag and It Lives!.

Strategy[edit | edit source]

At the start of each floor, 15►Blood Oath Blood Oath sets Bethany's health to half a heart and grants increased damage and speed. The key is to survive long enough to find hearts to refill her health so she won't die in one hit. The following items will make the run safer:

  • 15►Placenta Placenta/15►Old Bandage Old Bandage/15►Fanny Pack Fanny Pack/15►Yum Heart Yum Heart: Gives some red health in the starting room.
  • 15►Glyph of Balance Glyph of Balance: Champion enemies' drops and room drops are modified. By clearing rooms, Bethany will only find red hearts (or rotten hearts) until she's full healed. Pickups generated together with the room will not be replaced however.
  • 15►Judas' Shadow Judas' Shadow/15►Lazarus' Rags Lazarus' Rags: Allows changing into other characters who can take soul hearts for protection.
  • 15►Holy Mantle Holy Mantle/Wooden Cross Wooden Cross: Can now take a hit until finding red hearts.
  • Myosotis Myosotis: Can bring your red hearts to the next floor if you have spare ones lying on the ground.
  • 15►Dead Cat Dead Cat: Gives extra lives.
  • 15►Book of Shadows Book of Shadows: Can be activated to avoid being stabbed by Blood Oath. Receive no damage bonus in return.
  • Cards and pills that give health and/or invincibility, such as XIX - The Sun XIX - The Sun and Power Pill. Keep one of these for emergency use.

Be aware that 15►Blood Oath Blood Oath triggers the effect of taking damage multiple times depending on your hearts. Taking 15►Curse of the Tower Curse of the Tower can lead to spawning enormous number of troll bombs on a floor start.

Also, when Bethany only have one or half a heart, she may enter the Boss Challenge Room to gain more items. This comes with risk, though.

Unlockable achievements[edit | edit source]

MainPageChallenges.png Challenges MainPageChallenges.png

1. Pitch Black 2. High Brow 3. Head Trauma 4. Darkness Falls 5. The Tank 6. Solar System 7. Suicide King
8. Cat Got Your Tongue 9. Demo Man 10. Cursed! 11. Glass Cannon 12. When Life Gives You Lemons 13. Beans! 14. It's in the Cards
15. Slow Roll 16. Computer Savvy 17. Waka Waka 18. The Host 19. The Family Man 20. Purist
21. XXXXXXXXL 22. SPEED! 23. Blue Bomber 24. PAY TO PLAY 25. Have a Heart 26. I RULE! 27. BRAINS!
28. PRIDE DAY! 29. Onan's Streak 30. The Guardian
Afterbirth †
31. Backasswards 32. Aprils Fool 33. Pokey Mans 34. Ultra Hard 35. Pong
36. Scat Man 37. Bloody Mary 38. Baptism by Fire 39. Isaac's Awakening 40. Seeing Double 41. Pica Run 42. Hot Potato
43. Cantripped! 44. Red Redemption 45. DELETE THIS
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