

Blister is a trinket added in The Binding of Isaac: Afterbirth.
Effect[]
- Increases the knockback of Isaac's tears.
Tips[]
- This trinket is useful against chasing enemies and enemies that explode upon death such as
Mullibooms or
Boom Flies.
Synergies[]
8 Inch Nails /
Pisces: The knockback from Blister is stronger than from the items, and knockback boosts do not stack.
Brimstone: The beam pushes back enemies.
The Ludovico Technique: The controlled tear gains knockback.
Mom's Knife: The knife gains knockback.
- Piercing tears: Tears can again knock enemies back.
Tech.5 /
Tech X /
Technology /
Technology 2: Pushes the enemies back along the lasers. For Tech X, the direction is counter-clockwise around the ring.
Trisagion: Adds knockback, which can deal devastating damage to enemies caught in the blast.
In-game Footage[]
Trivia[]
- In real life, a blister is a small pocket of body fluid that forms within the upper layers of the skin.