Blindfolded

Blindfolded is a special condition originally exclusive to the Solar System, Cat Got Your Tongue, Beans!, and The Family Man challenges.

Several challenges (Blue Bomber, BRAINS! and The Guardian) and a character, Lilith, also employ the blindfolded condition.

Two challenges (Scat Man and Baptism by Fire), also employ the blindfolded condition.

When Isaac is blindfolded, he is unable to fire tears and most projectiles. It also prevents attacks from other firsthand sources, such as Mom's Knife, Brimstone, and Epic Fetus.

Since blindfolded is a challenge condition instead of an existing item, it cannot be removed with Dice Rooms, Missing No., or D100, and does not show up on the "My stuff!" screen. Despite being unable to fire tears, Isaac can still command familiars to shoot by holding the attack button, and can still use active items.

Trivia

• Both Lilith and The Guardian have different blindfolds that still function the same.