Blindfolded

Blindfolded is a special condition exclusive to certain challenges. The characters Lilith and Tainted Lilith are also blindfolded.

When Isaac is blindfolded, he is unable to fire tears and most projectiles. It also prevents attacks from other firsthand sources, such as Mom's Knife, Brimstone, and Epic Fetus. However, this does not prevent attacks from items such as Maw of the Void or Revelation. Despite being unable to fire tears, Isaac can still command familiars to shoot by holding the attack button, and can still use active items.

Since blindfolded is a challenge condition instead of an existing item, it cannot be removed with Dice Rooms, Missing No., or D100, and does not show up on the "My stuff!" screen, or be obtained with the debug menu.

• Rebirth challenges: Solar System, Cat Got Your Tongue, Beans!, and The Family Man.

• Afterbirth challenges: Blue Bomber, BRAINS! and The Guardian.

• Repentance challenges: Scat Man, Baptism by Fire, and Hot Potato.

Trivia

• Both Lilith and The Guardian have different blindfolds that still function the same.
• Hot Potato and Tainted Lilith do not visually have blindfolds, but the mechanic is still present.