Binding of Isaac: Rebirth Wiki
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After obtaining 3 fly items from the following list ((in Repentance) 3 items with the fly item tag), Isaac turns into a giant humanoid fly and gains flight. While in this form, most types of enemy flies will automatically be converted into Blue Flies. (in Repentance) Enemies such as Boom FlyBoom Flies and its variants will become friendly and be brought with Isaac to other rooms and floors.

Active Collectibles[ | ]

Name ID Icon Quote Description (in Repentance) Quality
(except in Rebirth) Jar of Flies 5.100.434
Jar of Flies
Unlimited
Bug catcher Killing an enemy adds a fly to the jar, up to a maximum of 20. On use, releases Blue Flies equal to the number of flies in the jar. 2
(in Repentance) Plum Flute 5.100.650
Plum Flute
4 rooms
Play time! Summons the boss Boss Baby Plum ingameBaby Plum to fight for Isaac in the current room. 1

Passive Collectibles[ | ]

Name ID Icon Quote Description (in Repentance) Quality
???'s Only Friend 5.100.320 ???'s Only Friend Controlled friend Spawns a controllable familiar that deals 37.5 damage per second on touch. It can be moved using the shooting directional keys 1
BBF 5.100.272 BBF Big Beautiful Fly Spawns a familiar that flies around the room in a zig-zag pattern and explodes on contact with an enemy. Respawns after ten seconds. 1
Best Bud 5.100.274 Best Bud Sworn protector When hit, spawns a quickly orbiting attack fly similar to Collectible Forever alone iconForever alone for the current room that deals high damage. 0
Big Fan 5.100.279 Big Fan Fat protector Spawns a large orbital familiar that blocks enemy shots and deals 30 damage per second to enemies. 2
Distant Admiration 5.100.57 Distant Admiration Attack fly Spawns an attack fly that circles further out than Collectible Halo of Flies iconHalo of Flies, but closer than Collectible Forever alone iconForever alone, dealing 75 damage per second. 2
Forever Alone 5.100.128 Forever Alone Attack fly Spawns an attack fly that orbits a long distance from Isaac, dealing 30 damage per second. 1
Halo of Flies 5.100.10 Halo of Flies Projectile protection Spawns two Pretty Flies that block enemy shots and deal contact damage to flies. 2
Hive Mind 5.100.248 Hive Mind Giant spiders and flies Increases the size of Blue Spiders and Blue Flies and doubles the amount of damage they deal. (in Repentance) Also increases the effectiveness of fly and spider familiars. 2
Skatole 5.100.9 Skatole Fly love Flies become harmless or less dangerous depending on the type. 0
Smart Fly 5.100.264 Smart Fly Revenge fly Spawns an orbital familiar that blocks enemy shots. Upon taking damage, the familiar will pursue enemies for the rest of the room, dealing 22.5 damage per second. 2
The Mulligan 5.100.151 The Mulligan They grow inside Tears have a 1/6 chance of spawning allied Blue Flies when they hit an enemy. 3
(except in Rebirth) Friend Zone 5.100.364 Friend Zone Friendly fly Spawns a white attack fly that orbits somewhere between Collectible Distant Admiration iconDistant Admiration and Collectible Forever alone iconForever alone, dealing 45 damage per second. 1
(except in Rebirth) Lost Fly 5.100.365 Lost Fly Lost protector Spawns fly familiar that moves in a straight line and circles around the first wall or obstacle it hits. (except in Repentance) It deals 105 damage per second on contact. (in Repentance) It deals 56 damage per second and forces nearby enemies to attack it. 2
(except in Rebirth) Obsessed Fan 5.100.426 Obsessed Fan Follows my every move... Spawns a familiar that follows Isaac's movements on a delay and deals 30 contact damage per second to enemies. 0
(except in Rebirth) Papa Fly 5.100.430 Papa Fly Turret follower Spawns a familiar that follows Isaac's movements on a 3 second delay, firing tears at nearby enemies. 1
(in Afterbirth † and Repentance) Angry Fly 5.100.511 Angry Fly He's violent Spawns a fly familiar that orbits around a random enemy and deals 30 damage per second to enemies it comes in contact with. 1
(in Repentance) Bot Fly 5.100.629 Bot Fly Defense drone Spawns an orbiting fly familiar that fires shielded tears at incoming enemy projectiles. 3
(in Repentance) Fruity Plum 5.100.649 Fruity Plum Bouncy friend Gives Isaac a miniature Boss Baby Plum ingameBaby Plum familiar that propels itself diagonally around the room, firing tears behind itself as it travels. 1
(in Repentance) Parasitoid 5.100.461 Parasitoid Egg tears! Adds a chance to fire an egg sack which creates slowing creep and spawns a Blue Fly or Blue Spider upon hitting an enemy. 3
(in Repentance) Psy Fly 5.100.581 Psy Fly Flamboyant protector Spawns a fly orbital familiar that chases and blocks enemy shots. 4
(in Repentance) The Swarm 5.100.693 The Swarm Infest Spawns eight orbital flies, which turn into Blue Flies after they block a shot. Each time a room is cleared, spawns another orbital fly. 2
(in Repentance) YO LISTEN! 5.100.492 YO LISTEN! Yo listen! +1 luck. Spawns a fairy familiar that points out Secret RoomSecret Rooms, Crawl SpaceCrawl Space entrances, and tinted rocks. 2

Notes[ | ]

  • Isaac starts with this transformation in the Solar System challenge.

Unlockable Achievements[ | ]

  • Lord of the Flies
    Lord of the Flies - Become Beelzebub.

Trivia[ | ]

  • Beelzebub, also known by "Lord of the Flies" and many other names, is known as one of the 7 princes of hell. Beelzebub is also another name for the devil.
  • In modern Catholic tradition, Beelzebub is regarded as one of the 7 princes of Hell; however, the origins of the name Beelzebub actually dates back to an early Jewish insult for worshippers of a Canaanite Deity Ba'al 'Lord', or Ba'al-Zvul 'Lord of the manor/dwelling', calling him Ba'al-Zvuv, 'Lord of the flies'.
    • The achievement 'Lord of the Flies' is a reference to this.


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