BFFS! is a passive item.
Effects
- Visually increases the size of all familiars by 25%, and improves the effectiveness of most of them.
- Doubles the damage of Familiars that deal damage through tears and contact damage.
- Only affects familiars that deal a set amount of damage. Has no effect on most familiars that scale with Isaac's damage.
- Has no effect on Creep generated by familiars.
- For pickup-generating familiars, increases the frequency that they drop pickups.
- Other familiars can be affected in subtle ways.
- Doubles the damage of Familiars that deal damage through tears and contact damage.
Notes
- The size change is only cosmetic: familiars' hitbox for blocking damage or attacking is not affected.
- Familiars summoned by a trinket or by
Monster Manual are also affected by BFFS!. - The Blue Flies and Blue Spiders benefit from Hive Mind instead.
- Does not increase the frequency or effectiveness of Status Effects applied by familiars.
Synergies
- BBF/Bob's Brain: Doubles impact damage and increases explosive damage by 25.
- Incubus/Fate's Reward: Deals double Isaac's damage instead of copying it.
- Juicy Sack: Spawns an extra Blue Spider.
- Orbitals: The damage is doubled as expected, but the hitbox for orbitals does not increase for additional protection or reach.
- Lil Spewer: Increases the creep pool's size, but not its damage.
- Mystery Egg: Spawns a champion variant of the enemy, even if the enemy can't normally be a champion.
Interactions
- Evil Eye: The eyes are not treated as familiars and therefore will not synergize with BFFS!
- Scissors: Doesn't change the head's size, but improves its damage.
- Shade: Retains the increased damage even after being absorbed.
No Effect
The following familiars will appear larger, but gain no actual benefits.
In-game Footage
Trivia
- BFF stands for Best Friends Forever.
- This item is used in The Family Man (challenge #19).
 Familiar Modifiers
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| Trinkets |
 The Binding of Isaac: Rebirth
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