BFFS! - Binding of Isaac: Rebirth Wiki

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BFFS! is a passive item.

Effects[]

Visually increases the size of all familiars by 25%, and improves the effectiveness of most of them.
- Doubles the damage of Familiars that deal damage through tears and contact damage.
  - Has no effect on Creep generated by familiars.
- For pickup-generating familiars, increases the frequency that they drop pickups.
  - Familiars that require clearing a certain number of rooms will require one less room.
  - Familiars that have a random chance to drop items have a higher chance.
  - Familiars that pick up consumables require less, except Dark Bum which is unaffected.
- Some familiars have unique synergies.

Notes[]

The size change is only cosmetic: familiars' hitbox for blocking damage or attacking is not affected.
Familiars summoned by a trinket or by Monster Manual are also affected by BFFS!.
- Wisps are also affected by BFFS!.
Blue Flies and Blue Spiders are not affected, they instead benefit from Hive Mind.
Does not increase the frequency or effectiveness of Status Effects applied by familiars.

Synergies[]

BBF/Bob's Brain: Doubles impact damage and increases explosive damage by 25.
Bird Cage: Spawns 4 rock waves in an x pattern. Doubles the damage when the bird lands and doubles contact damage. Damage of waves unaffected.
Blood Oath: Adds 2 extra full hearts worth of bonuses if any health is drained.
Holy Water: Double water damage and spawns a blue flame at point of impact.
Incubus: Shoots tears that do 2x Isaac's damage 1.5x Isaac's damage. Still deals 2x as Lilith.
Isaac's Heart: Fires additional shots in random directions and leaves a larger puddle of creep. Does not change the heart's size.
Juicy Sack: Spawns an extra Blue Spider.
Lil Spewer: Increases the creep pool's size, but not its damage.
Lost Soul: Gives the Lost Soul a Holy Mantle effect.
Mystery Egg: Spawns a champion variant of an enemy, even if the enemy normally can't be a champion.
Stitches: On use, fires eight tears from Isaac's original location. The tears synergize with Isaac's tear effects.
Succubus: The aura's radius increases, but the damage multiplier and damage to enemies remain the same.

Interactions[]

Blood Puppy: Only increases the damage and size while it isn't hostile.
Evil Eye: The eyes are not treated as familiars and therefore will not synergize with BFFS!
Guillotine/Scissors: Doesn't change the head's size, but still improves its damage.
Hive Mind: Does not stack.
Shade: Retains the increased damage even after being absorbed.

No Effect[]

The following familiars will appear larger, but gain no actual benefits.

In-game Footage[]

Trivia[]

BFF stands for Best Friends Forever.
This item is used in The Family Man (challenge #19) and Scat Man (challenge #36).

Familiar Modifiers

The Binding of Isaac: Rebirth

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