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Item icon
Item altar
"Your Friends Rule!"
Table dividing line 1.png
Item ID
Character Appearance
Character appearance
Table dividing line 2.png
Item Pool
Normal and hard modes only Shop Shop
Added in Afterbirth Greed and greedier modes only Shop Shop
Table dividing line 3.png
Collection Grid
Removed in Afterbirth(page 3, column 3, row 5)
Added in Afterbirth(page 3, column 3, row 1)

BFFS! is a passive item.

Effects[edit | edit source]

  • Visually increases the size of all familiars by 25%, and improves the effectiveness of most of them.
    • Doubles the damage of Familiars that deal damage through tears and contact damage.
      • Only affects familiars that deal a set amount of damage. Has no effect on most familiars that scale with Isaac's damage.
      • Has no effect on Creep generated by familiars.
    • For pickup-generating familiars, increases the frequency that they drop pickups.
      • Familiars that require clearing a certain number of rooms will require one less room.
      • Familiars that have a random chance to drop items have a higher chance.
      • Familiars that pick up consumables require less, except 15►Dark Bum Dark Bum which is unaffected.
    • Some familiars have unique synergies.

Notes[edit | edit source]

  • The size change is only cosmetic: familiars' hitbox for blocking damage or attacking is not affected.
  • Familiars summoned by a trinket or by 15►Monster Manual Monster Manual are also affected by BFFS!.
  • The Blue Flies and Blue Spiders benefit from 15►Hive Mind Hive Mind instead.
  • Does not increase the frequency or effectiveness of Status Effects applied by familiars.

Synergies[edit | edit source]

  • 15►BBF BBF/15►Bob's Brain Bob's Brain: Doubles impact damage and increases explosive damage by 25.
  • Added in Repentance15►Blood Oath Blood Oath: Adds 2 full hearts' worth of bonuses if any health is drained at all, e.g. losing 1 heart gives the bonuses of 3 hearts.
  • Added in Afterbirth15►Incubus Incubus/Added in Afterbirth15►Fate's Reward Fate's Reward: Deals double Isaac's damage instead of copying it.
  • Added in Repentance15►Holy Water Holy Water: Double water damage, spawn a blue flame at point of impact.
  • Removed in Repentance 15►Isaac's Heart Isaac's Heart: No effect.
    • Added in Repentance Increases the damage of the charged attack.
  • 15►Juicy Sack Juicy Sack: Spawns an extra Blue Spider.
  • Added in Afterbirth †15►Lil Spewer Lil Spewer: Increases the creep pool's size, but not its damage.
  • Added in Afterbirth †15►Mystery Egg Mystery Egg: Spawns a champion variant of the enemy, even if the enemy can't normally be a champion.
  • Added in Repentance15►Lost Soul Lost Soul: Gives the Lost Soul  Holy Mantle.

Interactions[edit | edit source]

  • Added in Afterbirth15►Evil Eye Evil Eye: The eyes are not treated as familiars and therefore will not synergize with BFFS!
  • 15►Guillotine Guillotine/15►Scissors Scissors: Doesn't change the head's size, but still improves its damage.
  • Orbitals: The damage is doubled as expected, but the hitbox for orbitals does not increase for additional protection or reach.
  • Added in Afterbirth †15►Shade Shade: Retains the increased damage even after being absorbed.

No Effect[edit | edit source]

The following familiars will appear larger, but gain no actual benefits.

In-game Footage[edit | edit source]

Trivia[edit | edit source]

  • BFF stands for Best Friends Forever.
  • This item is used in The Family Man (challenge #19).

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