Binding of Isaac: Rebirth Wiki
Binding of Isaac: Rebirth Wiki
Added in Repentance

The Ascent is a special sequence begun by obtaining 15►Dad's Note Dad's Note from the special versions of Mausoleum Mausoleum II/Gehenna Gehenna II. These floors can be accessed by opening the special door in the starting room of Depths Depths II or its variants. This door appears once the player has defeated Mother at least once. It involves going back up through abbreviated versions of every floor previously seen through beams of light. Much like the Backasswards Backasswards challenge, Isaac begins in the boss room of each floor and must find the beam of light, located in the corresponding starting room.

These abbreviated versions contain the same Treasure Rooms and Boss Rooms as they did previously, in almost the same condition.

All the other special rooms do not spawn.

Monsters not normally found on the current floor will appear, as well as unique room layouts and new monsters not found anywhere else in the game.

After leaving Mausoleum Mausoleum II, Isaac will begin taking double damage, as would otherwise occur on entering any variant of Womb Womb or Corpse Corpse.

Entering Basement Basement I's light beam will take Isaac to Home Home.


Unique Monsters[]

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This table lists all of the unique monsters that only spawn during the ascent. These enemies are based on normal enemies from the individual pre ascent chapters they are seen in, but have a twist to make them bigger and stronger, to challenge players with better stats.

Entity ID Description
Tainted Pooter
Tainted Pooter
14.2 Slowly drifts toward Isaac, occasionally firing four blood shots at him that split into two smaller ones when they hit a wall or obstacle.
Tainted Mulligan
Tainted Mulligan
22.3 Wanders around the room, avoiding Isaac and spawning 6 Ring Flies if he gets close. Spawns a plethora of fly enemies upon death.
Tainted Boom Fly
Tainted Boom Fly
25.6 Flies around the room diagonally, dealing contact damage. Upon death, sends explosions in a cross-shaped marker across the room.
Tainted Hopper
Tainted Hopper
29.3 Jumps and twirls around the room, shooting 4 rings of projectiles that increase in size with each shot.
Tainted Spitty
Tainted Spitty
31.1 Slowly moves around the room, firing chaotic bursts of blood shots in all directions and occasionally spitting a line of blood shots in the direction it's facing. Fires two rotating rings of blood shots upon death.
Tainted Sucker
Tainted Sucker
61.7 Flies slowly towards Isaac. Upon death, fires a radial burst of six blood shots that each also fires a radial burst of six blood shots.
Tainted Soy Creep
Tainted Soy Creep
240.3 Slowly crawls along walls to try to line up with Isaac and shoots a 4 diagonal streams of 15►Soy Milk Soy Milk shots.
Tainted Round Worm
Tainted Round Worm
244.2 Pops out of the ground in random locations alongside several tail ends. The head fires a large blood shot that splits into a radial burst of 8 blood shots, while the tail ends shoot normal blood shots.
Tainted Tube Worm
Tainted Tube Worm
244.3 Pops out of the ground in random locations, spitting 4 explosive shots towards Isaac.
Tainted Sub Horf
Tainted Sub Horf
812.1 Will only shoot when hit. Takes heavy knockback and rotates when hit. Shoots a lot faster and has bigger projectiles than its normal variant.
Tainted Faceless
Tainted Faceless
827.1 Wanders around the room, rarely firing a radial burst of six shots. Chases Isaac and fires shots very frequently after taking damage.
Tainted Mole
Tainted Mole
829.1 Dig towards Isaac and release a ring of rock waves. Fires 3 blood shots at Isaac 4 times.
Elleech
Elleech
855.1 Slowly moves around the room. After Isaac gets in its line of sight, continuously charges at him in the closest cardinal direction.


Regular Monsters[]

When the game makes a small mock floor to take the place of each original floor/chapter you Descended through before the ascent, it populates each new floor mostly with its pre-ascent biome/chapter specific enemies.(ex: boom flies in caves, gurgles in depths) However, the Ascent enemy pools are altered to allow enemies from later floors (Shadies outside of Sheol, Peeping Fatties and Para-Bites outside of the Womb, Cohorts outside of the Corpse)

These are the tables of enemies the game spawns to populate its specific Re-ascent mock chapters.

Mausoleum Mausoleum[]

Entity ID Description
Cursed Globin
Cursed Globin
24.3 Chases Isaac, dealing a full heart of contact damage. Upon taking enough damage, it collapses into 1-2 piles of goo, each of which can be killed and regenerate after a short period of time if not killed quickly. These goo piles have less health the more times the Cursed Globin splits.
Psychic Maw
Psychic Maw
26.2 Slowly floats towards Isaac, firing homing shots at him when he is in their range. Spawns with an Eternal Fly orbiting around it.
Vis Versa
Vis Versa
39.4 Randomly wanders around the room. Pauses to charge and fire a homing Brimstone laser when Isaac gets in its line of sight.
Loose Knight
Loose Knight
41.2 Moves erratically around the room, charges toward Isaac when in line of sight. When its health is depleted, it turns into a Brainless Knight and a Pon.
Brainless Knight
Brainless Knight
41.3 Alternates between running around the room along the cardinal directions and aimlessly walking in circles. Charges at Isaac when in line of sight. Dies when its corresponding Pon dies.
Death's Head
Death's Head
212.0 Invulnerable enemy that moves diagonally around the room, dealing contact damage. Dies when the room is cleared.
Cursed Death's Head
Cursed Death's Head
212.2 Invulnerable enemy that moves diagonally around the room, dealing contact damage. If Isaac enters its purple aura, he will be inflicted with fear and be temporarily unable to shoot. Dies when the room is cleared.
Brimstone Death's Head
Brimstone Death's Head
212.3 Invulnerable enemy that moves diagonally around the room, pausing to fire a 15►Brimstone Brimstone laser when Isaac lines up with it in the cardinal directions. Dies when the room is cleared.
Bony
Bony
227.0 Wanders around the room and throws a bone at Isaac when he is in sight.
Lil Portal
Lil Portal
306.1 Spawns fly and spider enemies until it is destroyed.
Bishop
Bishop
805.0 Shields all enemies in the room, preventing them from taking damage. Fires shots in the cardinal directions when it takes damage.
Kineti
Kineti
816.1 Uses telekinesis to pick up and throw rocks and obstacles at Isaac.
Candler
Candler
833.0 Flies around the room and propels itself by spawning flames.
Whipper
Whipper
834.0 Runs around the room, sprinting at Isaac when he gets in its line of sight and lashing at him when it gets close.
Snapper
Snapper
834.1 Runs around the room, sprinting at Isaac when he gets in its line of sight and throwing out its whip when he gets in range.
Flagellant
Flagellant
834.2 Runs around the room. When Isaac gets in its line of sight, continuously chases him and lashes its whip, occasionally deflecting Isaac’s shots.
Pon
Pon
840.0 Hops around the room, leaving damaging red creep wherever it lands. Upon death, its associated Brainless Knight dies with it.
Revenant
Revenant
841.0 Slowly wanders around the room, stopping to fire a large line of fire at the player.
Quad Revenant
Quad Revenant
841.1 Wanders around the room slowly, stopping to fire lines of flames in the cardinal or ordinal directions, rotating in an attempt to hit Isaac.
Morningstar
Morningstar
863.0 Floats toward Isaac to deal contact damage while Isaac is moving, gaining speed the longer Isaac continues moving. Stops moving when Isaac stops moving.
Grudge
Grudge
877.0 Quickly slides towards Isaac when he gets in its line of sight. Cannot be destroyed.
Baby Begotten
Baby Begotten
883.0 Floats toward Isaac, avoiding his shots. After getting close, fires a short 15►Brimstone Brimstone laser in the closest cardinal direction and propels itself away from him.
Cultist
Cultist
885.0 Creates an indestructible, homing Purple Ball at the start of the room and follows it around, occasionally leaving it to revive enemies that have died in the current room.
Blood Cultist
Blood Cultist
885.1 Wanders around the room and fires a line of blood shots and creep if Isaac is on either side of it. Can summons bone traps that temporarily ensnare Isaac if he walks into them.
Vis Fatty
Vis Fatty
886.0 Spawns with a Fetal Demon attached to it and slowly walks towards Isaac. Will occasionally fart, briefly pushing the demon away and spawning creep around itself and the demon. If the Fatty is killed first, the Fetal Demon will chase Isaac similarly to Gemini's Suture. If the demon is killed first, the Fatty will shoot out 15►Brimstone Brimstone in the diagonal direction closest to Isaac. It will then fly around the room diagonally, bumping off of walls and tall blocks all while continuously firing 15►Brimstone Brimstone behind it.
Fetal Demon
Fetal Demon
886.1 Usually encountered tethered to Vis Fatties. When tethered it makes short lunges towards Isaac if he gets close. If the Vis Fatty is killed or when encountered alone it will chase Isaac similarly to Gemini's Suture.
Shady
Shady
888.0 Walks toward Isaac, occasionally firing a shot that creates shots perpendicular to itself while traveling and splits into a ring of shots upon hitting a wall or obstacle. Also occasionally jumps, creating lines of explosions in the cardinal directions.
Maze Roamer
Maze Roamer
890.0 Wanders around the room and shoots an eyeball at Isaac when he is in sight. Has a clone of itself on the other side of the room that mimics its movement and shots. If one dies, the other starts actively pursuing Isaac.
Goat
Goat
891.0 Wanders around the room. Occasionally moves toward Isaac, either firing blood shots at him or charging if he lines up on either side of it.
Black Goat
Black Goat
891.1 Wanders around the room. Occasionally moves toward Isaac, either firing blood shots at him or charging if he lines upon either side of it. Can also fire thin 15►Brimstone Brimstone lasers in the cardinal directions, along with all other Black Goats in the room.
Ball and Chain
Ball and Chain
893.0 Spike balls that rotate at the end of a chain attached to an obstacle. If the obstacle is destroyed, the ball will fly free around the room for a while.

Depths Depths[]

Entity ID Description
Attack Fly
Attack Fly
18.0 Red fly that follows Isaac and deals contact damage.
Hive
Hive
22.0 Wanders around the room, avoiding Isaac and spawning Attack Flies if he gets close. Spawns a large number of flies on death, which can be Black Flies, Attack Flies, and/or Pooters.
Gazing Globin
Gazing Globin
24.1 Quickly chases Isaac, dealing a full heart of contact damage. Upon taking enough damage, it collapses into a pile of goo, which will slide away from Isaac and can be killed. Will regenerate after a short period of time if not killed quickly.
Boom Fly
Boom Fly
25.0 Flies around the room diagonally, dealing contact damage. Explodes upon death.
Maw
Maw
26.0 Slowly floats towards Isaac, firing blood shots at him when he is in their range.
Red Maw
Red Maw
26.1 Floats towards Isaac and releases 4 blood shots in the cardinal directions upon death.
Psychic Maw
Psychic Maw
26.2 Slowly floats towards Isaac, firing homing shots at him when he is in their range. Spawns with an Eternal Fly orbiting around it.
Host
Host
27.0 Stationary enemy that is normally invulnerable. Raises its head up when Isaac gets close, revealing a fleshy stem that can be damaged. Upon raising its head, it will fire 3 blood shots in a spread and lower its head again.
Eggy
Eggy
29.2 Hops aimlessly around the room, spawning slowing white creep wherever it hops. Spawns a group of Swarm Spiders upon death.
Brain
Brain
32.0 Slowly crawls around the room, leaving a trail of Red Creep.
Leaper
Leaper
34.0 Hops around the room, doing contact damage. Occasionally jumps high into the air, dropping down onto Isaac's position while firing 4 blood shots in the cardinal directions.
Mr. Maw
Mr. Maw
35.0 Walks towards Isaac and attacks by launching its head towards him. Turns into a Maw or Gusher upon death depending on the killed body segment. Occasionally separates at will.
Mr. Red Maw
Mr. Red Maw
35.2 Walks towards Isaac and attacks by launching its head towards him. Turns into a Red Maw or Gusher upon death depending on the killed body segment. Occasionally separates at will.
Baby
Baby
38.0 Slowly floats towards Isaac and fires a blood shot at him. Occasionally teleports and reappears elsewhere.
Wrinkly Baby
Wrinkly Baby
38.3 Lunges towards Isaac at high speed and fires three blood shots in his direction once stopped.
Vis
Vis
39.0 Randomly wanders around the room. Pauses to charge and fire a Brimstone laser when Isaac gets in its line of sight.
Chubber
Chubber
39.2 Randomly wanders around the room. Pauses to fire a Charger that deals one heart of damage when Isaac gets in its line of sight. The Charger is invulnerable, blocks Isaac's tears, has limited range, and flies back to the Chubber.
Scarred Double Vis
Scarred Double Vis
39.3 Randomly wanders around the room. Pauses to charge and fire a Brimstone laser which fires from all four cardinal sides when Isaac gets in its line of sight.
Knight
Knight
41.0 Moves erratically around the room and charges towards Isaac when in line of sight. Can only be damaged from behind.
Stone Grimace
Stone Grimace
42.0 Stationary and invulnerable monster that occasionally fires a blood shot at Isaac. Stops firing when room is cleared.
Triple Grimace
Triple Grimace
42.2 Stationary and invulnerable monster that occasionally fires a triple shot at Isaac. Stops firing when room is cleared.
Slide
Slide
44.1 Quickly slides towards Isaac when he gets in its line of sight, then moves slowly back to its original position. Cannot be destroyed.
MemBrain
MemBrain
57.0 Slowly moves around the room, occasionally hopping and firing 8 large blood shots in all directions. Splits into 2 Brains upon death.
Sucker
Sucker
61.0 Flies slowly towards Isaac, exploding into 4 shots in the cardinal directions upon death.
Embryo
Embryo
77.0 Aimlessly hops around the room, dealing contact damage.
Gurgle
Gurgle
87.0 Walks towards Isaac, firing Ipecac shots at him. Can turn into a Splasher upon death.
Walking Boil
Walking Boil
88.0 Does not shrink or regenerate. Walks around aimlessly and fires multiple short-ranged blood projectiles in random directions.
Walking Gut
Walking Gut
88.1 Does not shrink or regenerate. Walks around aimlessly and fires 15►Ipecac Ipecac shots in random directions.
Hanger
Hanger
90.0 Floats around the room, firing 3 spread blood shots at Isaac. Upon damaging Isaac, Isaac drops 2 coins on the ground but loses 3. Spawns with an Eternal Fly circling around it.
Swarmer
Swarmer
91.0 Slowly floats around the room, spawning several Attack Flies. Spawns Pooters upon taking damage. Spawns a Boom Fly upon death.
Mask + Heart
Mask + Heart
92.0 The Mask is invulnerable and moves around erratically, charging at Isaac when he lines up with it. The Heart avoids Isaac and fires 4 blood shots in the cardinal directions when Isaac gets near. Killing the Heart will automatically kill the Mask.
Mask II + 1/2 Heart
Mask II + 1/2 Heart
92.1 The Mask is invulnerable and moves around erratically, charging at Isaac when he lines up with it. The Heart avoids Isaac and fires 4 blood shots in the ordinal directions when Isaac gets near. Killing the Heart will automatically kill the Mask. If there are more than one 1/2 Heart in the room, they will fire blood shots between each other.
Constant Stone Shooter
Constant Stone Shooter
202.0 Stationary and invulnerable monster that continuously fires shots in a single direction.
Cross Stone Shooter
Cross Stone Shooter
202.10 Stationary and invulnerable monster that continuously fires shots in four directions, alternating between cardinal and ordinal.
Pale Fatty
Pale Fatty
208.2 Slowly walks towards Isaac. Occasionally farts and shoots 6 blood shots in all directions. Has a chance to turn into a Blubber or Half Sack upon death.
Fat Sack
Fat Sack
209.0 Slowly walks towards Isaac. Occasionally leaps off-screen and attempts to land on Isaac, leaving a puddle of Red Creep and shooting 6 blood shots in all directions where it lands. Has a chance to turn into a Blubber or Half Sack upon death.
Half Sack
Half Sack
211.0 Wanders around aimlessly and leaves a trail of Red Creep.
Death's Head
Death's Head
212.0 Invulnerable enemy that moves diagonally around the room, dealing contact damage. Dies when the room is cleared.
Rotty
Rotty
226.1 Slowly walks towards Isaac, leaving short-lasting Red Creep behind itself. Spawns a Bony or two Attack Flies upon death.
Bony
Bony
227.0 Wanders around the room and throws a bone at Isaac when he is in sight.
One Tooth
One Tooth
234.0 Follows Isaac and periodically dashes towards him when it gets close. Deals contact damage.
Grub
Grub
239.0 Erratically moves around the room like Larry Jr. and charges at Isaac when he gets within its line of sight. Spawns Maggots, Chargers, or Spitties upon death, one for each of its segments.
Rage Creep
Rage Creep
241.0 Slowly crawls along walls to try to line up with Isaac and shoots a Brimstone laser.
Floating Knight
Floating Knight
254.0 Behaves like the Knight but slower, and can fly over all obstacles.
Lil' Haunt
Lil' Haunt
260.0 Floats toward Isaac and occasionally fires a blood shot at him, predicting his movements.
Black Bony
Black Bony
277.0 Wanders around the room and throws three bones in a row at Isaac when he is in sight. Explodes upon death.
Poison Mind
Poison Mind
301.0 Slowly crawls/floats around the room diagonally, leaving a trail of damaging green creep. Explodes upon death.
Cohort
Cohort
857.0 Acts similarly to Monstro, hopping towards Isaac and using one of two projectile patterns. Spawns four Globins upon death.
Migraine
Migraine
869.0 Crawls around the room erratically, following Isaac and dealing contact damage. Can jump small distances. Releases multiple Troll Bombs upon death.
Needle
Needle
881.0 Pops out of the ground and lunges towards Isaac, dealing contact damage.
Shady
Shady
888.0 Walks toward Isaac, occasionally firing a shot that creates shots perpendicular to itself while traveling and splits into a ring of shots upon hitting a wall or obstacle. Also occasionally jumps, creating lines of explosions in the cardinal directions.
Degraded Bosses

Mines Mines[]

Entity ID Description
Dragon Fly
Dragon Fly
25.3.0 Flies around the room diagonally, dealing contact damage. Upon death, creates four lines of fire in the cardinal directions.
Dragon Fly X
Dragon Fly X
25.3.1 Flies around the room diagonally, dealing contact damage. Upon death, creates four lines of fire in the ordinal directions.
Bone Fly
Bone Fly
25.4 Flies around the room diagonally, dealing contact damage. Fires bones at Isaac if he lines up with it in the cardinal directions. Fires a radial burst of 3 bones upon death.
Hard Host
Hard Host
27.3 Stationary enemy that is normally invulnerable. Raises its head up when Isaac gets close, revealing a fleshy stem that can be damaged. Shortly after raising its head, it slams its head down and fires a rock wave towards Isaac.
Stone Grimace
Stone Grimace
42.0 Stationary and invulnerable monster that occasionally fires a blood shot at Isaac. Stops firing when room is cleared.
Ink
Ink
61.3 Flies slowly towards Isaac. Fires four tar shots in the ordinal directions and leaves a puddle of slowing black creep upon death.
Gurgle
Gurgle
87.0 Walks towards Isaac, firing Ipecac shots at him. Can turn into a Splasher upon death.
Crackle
Crackle
87.1 Walks toward Isaac, spitting balls of fire that create lines of fire in the cardinal directions on impact.
Bony
Bony
227.0 Wanders around the room and throws a bone at Isaac when he is in sight.
Soy Creep
Soy Creep
240.1 Slowly crawls along walls to try to line up with Isaac and shoots a stream of shots seemingly affected by 15►Soy Milk Soy Milk.
Stoney
Stoney
302.0 Chases Isaac and blocks tears, but does not deal contact damage. Temporarily pauses in exhaustion after a certain amount of time. Invulnerable; dies when the room is cleared.
Quake Grimace
Quake Grimace
804.0 Stationary and invulnerable monster that jumps and fires a line of rocks in one direction upon landing.
Bomb Grimace
Bomb Grimace
809.0 Stationary and invulnerable monster that keeps a single Throwable Bomb spawned.
Rock Spider
Rock Spider
818.0 Slowly crawls around the room. If it sees Isaac, it crawls at him, trying to deal contact damage. Turns into a Spider upon death. Turns into a Coal Spider if it touches fire.
Coal Spider
Coal Spider
818.2 Quickly crawls around the room. If it sees Isaac, it crawls at him, trying to deal contact damage. Turns into a hot coal upon death that blocks shots and deals contact damage, but can be destroyed.
Fly Bomb
Fly Bomb
819.0 Flies toward Isaac, circling around him as it does. Turn into a tiny bomb upon death.
Danny
Danny
820.0 Walks toward Isaac and spits chaotic bursts of rocks at him, some of which may be Rock Spiders.
Coal Boy
Coal Boy
820.1 Walks toward Isaac and spits hot coals at him, some of which may be Coal Spiders.
Blaster
Blaster
821.0 Slowly wanders around and occasionally shoots Fly Bombs at Isaac.
Bouncer
Bouncer
822.0 Wanders around the room, avoiding Isaac. If Isaac stays close to one for long enough, it inflates and starts chasing him, gaining a chance to deflect shots and causing it to explode into lingering blood shots on death.
Quakey
Quakey
823.0 Attempts to jump on Isaac, shooting out 8 rock shots when it hits the ground.
Gyro
Gyro
824.0 Rolls around like a wheel. Charges at Isaac when he is in line of sight, bouncing off of walls and obstacles as it does.
Grilled Gyro
Grilled Gyro
824.1 Rolls around like a wheel. Charges at Isaac when he is in line of sight, bouncing off of walls and obstacles and creating fires behind itself as it does.
Fire Worm
Fire Worm
825.0 Pops out of the ground in random locations and fires one flame at Isaac.
Hardy
Hardy
826.0 Dashes toward Isaac and deals contact damage creating rock projectiles when it hits a wall/obstacle. It spawns more rock projectiles the more times it crashes into obstacles, dying after doing so a third time.
Faceless
Faceless
827.0 Wanders around the room, rarely firing a radial burst of six shots. Chases Isaac and fires shots more frequently after taking damage.
Necro
Necro
828.0 Stationary enemy that summons unlimited-ranged bones to attack Isaac.
Mole
Mole
829.0 Burrows towards Isaac and jumps out the ground to fire 3 blood shots at him.
Big Bony
Big Bony
830.0 Walks slowly toward Isaac, and will occasionally fire a bone that bounces around the room for a few moments. The bone can be broken if shot enough.
Migraine
Migraine
869.0 Crawls around the room erratically, following Isaac and dealing contact damage. Can jump small distances. Releases multiple Troll Bombs upon death.
Flesh Maiden
Flesh Maiden
880.0 Vaguely flies towards Isaac in curved swooping motions.
Dust
Dust
882.0 Follows Isaac, and is only visible when close to Isaac. Will begin to speed up when they are visible. Teleports away after taking enough damage.
Dusty Death's Head
Dusty Death's Head
887.0 Invulnerable enemy that moves across the room in a waving motion in large quantities. Dies when the room is cleared.

Caves Caves[]

Entity ID Description
I.Blob
I.Blob
15.2 Randomly wanders around the room, firing 8 shots in all directions.
Charger
Charger
23.0 Slowly moves around the room, charging at Isaac when he gets in its line of sight.
Globin
Globin
24.0 Chases Isaac, dealing a full heart of contact damage. Upon taking enough damage, it collapses into a pile of goo, which can be killed. Will regenerate after a short period of time if not killed quickly.
Gazing Globin
Gazing Globin
24.1 Quickly chases Isaac, dealing a full heart of contact damage. Upon taking enough damage, it collapses into a pile of goo, which will slide away from Isaac and can be killed. Will regenerate after a short period of time if not killed quickly.
Boom Fly
Boom Fly
25.0 Flies around the room diagonally, dealing contact damage. Explodes upon death.
Red Boom Fly
Red Boom Fly
25.1 Flies around the room diagonally, dealing contact damage. Creates a ring of 6 blood shots upon death.
Maw
Maw
26.0 Slowly floats towards Isaac, firing blood shots at him when he is in their range.
Red Maw
Red Maw
26.1 Floats towards Isaac and releases 4 blood shots in the cardinal directions upon death.
Host
Host
27.0 Stationary enemy that is normally invulnerable. Raises its head up when Isaac gets close, revealing a fleshy stem that can be damaged. Upon raising its head, it will fire 3 blood shots in a spread and lower its head again.
Red Host
Red Host
27.1 Stationary enemy that can be damaged even when its head is lowered. Fire 5 spread blood shots when it raises its head.
Eggy
Eggy
29.2 Hops aimlessly around the room, spawning slowing white creep wherever it hops. Spawns a group of Swarm Spiders upon death.
Boil
Boil
30.0 Stationary enemy that decreases in size when hit, but regenerates to its full size until fully destroyed. Fires multiple short-ranged blood projectiles in random directions when fully swollen.
Spitty
Spitty
31.0 Slowly moves around the room, occasionally firing a single blood shot forward.
Mr. Maw
Mr. Maw
35.0 Walks towards Isaac and attacks by launching its head towards him. Turns into a Maw or Gusher upon death depending on the killed body segment. Occasionally separates at will.
Mr. Red Maw
Mr. Red Maw
35.2 Walks towards Isaac and attacks by launching its head towards him. Turns into a Red Maw or Gusher upon death depending on the killed body segment. Occasionally separates at will.
Chubber
Chubber
39.2 Randomly wanders around the room. Pauses to fire a Charger that deals one heart of damage when Isaac gets in its line of sight. The Charger is invulnerable, blocks Isaac's tears, has limited range, and flies back to the Chubber.
Stone Grimace
Stone Grimace
42.0 Stationary and invulnerable monster that occasionally fires a blood shot at Isaac. Stops firing when room is cleared.
Vomit Grimace
Vomit Grimace
42.1 Stationary and invulnerable monster that occasionally fires an Ipecac shot at Isaac. Stops firing when room is cleared.
Triple Grimace
Triple Grimace
42.2 Stationary and invulnerable monster that occasionally fires a triple shot at Isaac. Stops firing when room is cleared.
Sucker
Sucker
61.0 Flies slowly towards Isaac, exploding into 4 shots in the cardinal directions upon death.
Spit
Spit
61.1 Flies slowly towards Isaac, firing an Ipecac shot towards Isaac upon death.
Keeper
Keeper
86.0 Hops around the room, firing 2 blood shots in a V formation at Isaac. Upon damaging Isaac, Isaac drops 2 coins on the ground but loses 3.
Gurgle
Gurgle
87.0 Walks towards Isaac, firing Ipecac shots at him. Can turn into a Splasher upon death.
Walking Boil
Walking Boil
88.0 Does not shrink or regenerate. Walks around aimlessly and fires multiple short-ranged blood projectiles in random directions.
Walking Gut
Walking Gut
88.1 Does not shrink or regenerate. Walks around aimlessly and fires 15►Ipecac Ipecac shots in random directions.
Buttlicker
Buttlicker
89.0 Can start Attached to other Buttlickers and erratically moves around the room, similar to Larry Jr..
Constant Stone Shooter
Constant Stone Shooter
202.0 Stationary and invulnerable monster that continuously fires shots in a single direction.
Fat Sack
Fat Sack
209.0 Slowly walks towards Isaac. Occasionally leaps off-screen and attempts to land on Isaac, leaving a puddle of Red Creep and shooting 6 blood shots in all directions where it lands. Has a chance to turn into a Blubber or Half Sack upon death.
Squirt
Squirt
220.0 Dashes towards Isaac and deals contact damage. Spawns 2 Dips upon death.
Dinga
Dinga
223.0 Slowly moves around the room, occasionally hopping to spawn Dips or fire 8 Brown shots in all directions. Splits 2 Squirts upon death.
One Tooth
One Tooth
234.0 Follows Isaac and periodically dashes towards him when it gets close. Deals contact damage.
Blind Creep
Blind Creep
242.0 Randomly crawls along walls and shoots three spread blood shots.
Conjoined Spitty
Conjoined Spitty
243.0 Slowly moves around the room, occasionally firing a blood shot from both ends of its body.
Ticking Spider
Ticking Spider
250.0 Crawls around the room erratically, following Isaac and dealing contact damage. Can jump small distances. Explodes upon death.
Dart Fly
Dart Fly
256.0 Flies towards Isaac and attempts to predict his movements. Deals contact damage.
Conjoined Fatty
Conjoined Fatty
257.0 Slowly walks towards Isaac. Occasionally pauses to fart out a line of damaging Green Creep towards Isaac. Chance to turn into a regular Fatty upon death.
Mega Clotty
Mega Clotty
282.0 Slowly moves around the room, occasionally hopping and either firing 6 blood shots in all directions, leaving a puddle of Red Creep, or spawning a Clotty or a collapsed Globin. Splits into two Clotties upon death.
Dukie
Dukie
288.0 Flies around the room diagonally, occasionally spitting out 1-2 Dart Flies.
Blister
Blister
303.0 Slowly hops towards Isaac, occasionally spawning a Dark Ball. Spawns a Sack upon death.
Ministro
Ministro
305.0 Hops towards Isaac, occasionally spitting out a cluster of disorganized shots.
Peeping Fatty
Peeping Fatty
835.0 Has two indestructible eyeballs that are out of their sockets but attached by muscles. Wanders around the room randomly, or toward Isaac if its eyes see him. Occasionally farts and fires a radial burst of 6 blood shots.
Army Fly
Army Fly
868.0 Chases Isaac, moving along the cardinal directions. Forms a line with other Army Flies in the room. Deals contact damage.
Migraine
Migraine
869.0 Crawls around the room erratically, following Isaac and dealing contact damage. Can jump small distances. Releases multiple Troll Bombs upon death.
Needle
Needle
881.0 Pops out of the ground and lunges towards Isaac, dealing contact damage.
Degraded Bosses

Downpour Downpour[]

Entity ID Description
Frowning Gaper
Frowning Gaper
10.0 Walks towards Isaac, dealing contact damage. Upon getting near Isaac, it will open its eyes and pursue Isaac faster. Usually turns into a Pacer or a Gusher upon death.
Gaper
Gaper
10.1 Walks towards Isaac, dealing contact damage. Usually turns into a Pacer or a Gusher upon death.
Attack Fly
Attack Fly
18.0 Red fly that follows Isaac and deals contact damage.
Tube Worm
Tube Worm
244.1 Pops out of the ground in random locations and fires a long-range spray of arcing shots where Isaac will be.
Lil' Haunt
Lil' Haunt
260.0 Floats toward Isaac and occasionally fires a blood shot at him, predicting his movements.
Bubbles
Bubbles
806.0 Slowly walks towards Isaac, firing back shots upon taking damage. Occasionally farts, which pushes Isaac and adjacent enemies away and creates a chaotic burst of shots. Creates a geyser of water shots upon death.
Wraith
Wraith
807.0 Walks toward Isaac, dealing contact damage. Can only be seen through its reflection and ripples it leaves in the water as it moves.
Willo
Willo
808.0 Flies in a circle around Isaac (in formation with other Willos if available), keeping an exact distance away from him. One Willo at a time will occasionally light up and fire a shot at Isaac.
Small Leech
Small Leech
810.0 Chases Isaac continuously, not stopping at walls. Able to swim over gaps.
Deep Gaper
Deep Gaper
811.0 Emerges off the floor once all previous enemies have been killed, then proceeds to chase Isaac like a normal Gaper.
Sub Horf
Sub Horf
812.0 Stationary enemy that spins and fires shots while being moved around or knocked back.
Blurb
Blurb
813.0 Walks slowly towards Isaac. After taking some damage or getting close to Isaac, it fires a chaotic burst of tears at him and chases him more quickly.
Strider
Strider
814.0 Erratically swims around the room. If it sees Isaac, it chases him, trying to deal contact damage.
Fissure
Fissure
815.0 Jumps out of pits and bounces around the room. Spawns endlessly from pits until room clear. Do not need to be killed to clear room.
Polty
Polty
816.0 Picks up and throws rocks and props at Isaac.
Prey
Prey
817.0 Wanders around the room, avoiding Isaac and spawning Small Leeches if he gets close. Spawns 3 Small Leeches upon death.
Mullighoul
Mullighoul
817.1 Wanders around the room, avoiding Isaac and spawning Willos if he gets close. Spawns 1-2 Willos upon death.
Level 2 Willo
Level 2 Willo
838.0 Orbits enemies and shoots tears at Isaac. If the enemy it is orbiting dies, it will orbit another enemy. However, if all enemies are dead, it will chase Isaac, while still occasionally shooting at Isaac.
Drip
Drip
870.0 Quickly rolls around in diagonal directions, dealing contact damage.
Splurt
Splurt
871.0 Dashes towards Isaac twice and deals contact damage. Spawns 2 Drips upon death.
Fly Trap
Fly Trap
873.0 Floats towards Isaac, with 3 Attack Flies circling around it. Coughs up additional Attack Flies and releases gas to launch the Attack Flies outwards.
Dump
Dump
876.0 Slides toward Isaac, leaving a trail of slippery brown creep. After taking enough damage, its head slides off and quickly bounces around the room and its body spews out brown shots until it empties.
Bloaty
Bloaty
879.0 Lumbers around, occasionally spitting green shots and a line of damaging green creep in a random direction.

Basement Basement[]

Entity ID Description
Frowning Gaper
Frowning Gaper
10.0 Walks towards Isaac, dealing contact damage. Upon getting near Isaac, it will open its eyes and pursue Isaac faster. Usually turns into a Pacer or a Gusher upon death.
Gaper
Gaper
10.1 Walks towards Isaac, dealing contact damage. Usually turns into a Pacer or a Gusher upon death.
Gusher
Gusher
11.0 Walks aimlessly around the room, occasionally firing a short-ranged blood shot.
Horf
Horf
12.0 Stationary enemy that fires a medium-ranged blood shot at Isaac when he gets in range of them.
Fly
Fly
13.0 Hovers in place. Does not deal contact damage and is harmless but can turn into Pooters if they stay around Poop.
Pooter
Pooter
14.0 Slowly drifts toward Isaac, occasionally firing a single blood shot at him. Does not deal contact damage.
Grilled Clotty
Grilled Clotty
15.3 Quickly and randomly wanders around the room, firing four flame shots in the cardinal directions at a slight angle.
Mulligan
Mulligan
16.0 Walks around the room, avoiding Isaac. Upon death, spawns several flies, which can be Black Flies, Attack Flies, and/or Pooters. Can suicide to explode and launch four projectiles in the cardinal directions while still releasing flies.
Mulliboom
Mulliboom
16.2 Chases Isaac and explodes upon death or upon touching Isaac. The explosion deals a half-heart of damage instead of the regular full heart.
Attack Fly
Attack Fly
18.0 Red fly that follows Isaac and deals contact damage.
Red Boom Fly
Red Boom Fly
25.1 Flies around the room diagonally, dealing contact damage. Creates a ring of 6 blood shots upon death.
Hopper
Hopper
29.0 Slowly hops around the room, doing contact damage. Can turn into a Flaming Hopper by jumping into fire.
Leaper
Leaper
34.0 Hops around the room, doing contact damage. Occasionally jumps high into the air, dropping down onto Isaac's position while firing 4 blood shots in the cardinal directions.
Vis
Vis
39.0 Randomly wanders around the room. Pauses to charge and fire a Brimstone laser when Isaac gets in its line of sight.
Flaming Hopper
Flaming Hopper
54.0 Quickly hops around the room, doing contact damage. Covers a larger distance than the regular Hopper.
Para-Bite
Para-Bite
58.0 Moves towards Isaac, dealing contact damage. Can burrow underground and reappear elsewhere.
Sucker
Sucker
61.0 Flies slowly towards Isaac, exploding into 4 shots in the cardinal directions upon death.
Spit
Spit
61.1 Flies slowly towards Isaac, firing an Ipecac shot towards Isaac upon death.
Soul Sucker
Soul Sucker
61.2 Flies slowly towards Isaac. Spawns a vortex that fires four Brimstone beams in the cardinal directions upon death.
Ink
Ink
61.3 Flies slowly towards Isaac. Fires four tar shots in the ordinal directions and leaves a puddle of slowing black creep upon death.
Moter
Moter
80.0 Follows Isaac, similar to Attack Flies. Deals contact damage. Splits into 2 Attack Flies upon death.
Hanger
Hanger
90.0 Floats around the room, firing 3 spread blood shots at Isaac. Upon damaging Isaac, Isaac drops 2 coins on the ground but loses 3. Spawns with an Eternal Fly circling around it.
Big Spider
Big Spider
94.0 Erratically moves around the room. If Isaac gets close to it, it chases him, trying to deal contact damage. Spawns two Spiders upon death.
Constant Stone Shooter
Constant Stone Shooter
202.0 Stationary and invulnerable monster that continuously fires shots in a single direction.
Fatty
Fatty
208.0 Slowly walks towards Isaac. Occasionally farts, which pushes Isaac and adjacent enemies away.
Pale Fatty
Pale Fatty
208.2 Slowly walks towards Isaac. Occasionally farts and shoots 6 blood shots in all directions. Has a chance to turn into a Blubber or Half Sack upon death.
Dip
Dip
217.0 Slowly dashes in random directions, dealing contact damage.
Squirt
Squirt
220.0 Dashes towards Isaac and deals contact damage. Spawns 2 Dips upon death.
Ring Fly
Ring Fly
222.0 Gathers with any other Ring Flies in the room. These flies orbit around themselves while following Isaac. Deals contact damage.
Dinga
Dinga
223.0 Slowly moves around the room, occasionally hopping to spawn Dips or fire 8 Brown shots in all directions. Splits 2 Squirts upon death.
Rotty
Rotty
226.1 Slowly walks towards Isaac, leaving short-lasting Red Creep behind itself. Spawns a Bony or two Attack Flies upon death.
Round Worm
Round Worm
244.0 Pops out of the ground in random locations and spits a blood shot at Isaac if he is in sight.
Full Fly
Full Fly
249.0 Flies toward Isaac erratically, dealing contact damage. Releases 6 bullets in all directions upon death.
Ticking Spider
Ticking Spider
250.0 Crawls around the room erratically, following Isaac and dealing contact damage. Can jump small distances. Explodes upon death.
Lil' Haunt
Lil' Haunt
260.0 Floats toward Isaac and occasionally fires a blood shot at him, predicting his movements.
Roundy
Roundy
276.0 Pops out of the ground in random locations, creating a small rock wave. Fires an explosive Ipecac shot at Isaac if he is in sight.
Mega Clotty
Mega Clotty
282.0 Slowly moves around the room, occasionally hopping and either firing 6 blood shots in all directions, leaving a puddle of Red Creep, or spawning a Clotty or a collapsed Globin. Splits into two Clotties upon death.
Cyclopia
Cyclopia
284.0 Walks towards Isaac, dealing contact damage and leaving behind a short-lasting trail of damaging Red Creep. Occasionally shoots a blood shot towards Isaac.
Stoney
Stoney
302.0 Chases Isaac and blocks tears, but does not deal contact damage. Temporarily pauses in exhaustion after a certain amount of time. Invulnerable; dies when the room is cleared.
Ministro
Ministro
305.0 Hops towards Isaac, occasionally spitting out a cluster of disorganized shots.
Sub Horf
Sub Horf
812.0 Stationary enemy that spins and fires shots while being moved around or knocked back.
Faceless
Faceless
827.0 Wanders around the room, rarely firing a radial burst of six shots. Chases Isaac and fires shots more frequently after taking damage.
Army Fly
Army Fly
868.0 Chases Isaac, moving along the cardinal directions. Forms a line with other Army Flies in the room. Deals contact damage.
Migraine
Migraine
869.0 Crawls around the room erratically, following Isaac and dealing contact damage. Can jump small distances. Releases multiple Troll Bombs upon death.
Degraded Bosses

Notes[]

  • If any variant floors were encountered during descent, all floors of the Ascent will still be the original ones. For example, if the second floor on a run was Cellar Cellar II or Burning Basement Burning Basement II , during the Ascent it will be replaced by Basement Basement II regardless.
  • Isaac won't encounter any curses during the Ascent, except Curse of the Labyrinth if it was on the original floor.
    • When encountering Curse of the Blind, it may be a good idea to skip boss and treasure room items, as they will be revealed during the Ascent.
    • XL floors in Ascent will contain both Treasure Rooms from the original floor.
  • Red treasure rooms found through the 15►Red Key Red Key during the original run will automatically show up during the Ascent, and will be adjacent to normal rooms. These doors do not require keys to open.
  • Any unopened Treasure Rooms on previous floors will still be locked during the Ascent.
    • If these skipped Treasure Rooms are entered during the ascent, they will contain different items. This is best viewed with the effect of 15►Dream Catcher Dream Catcher.
    • This also means a strategy is to skip Treasure Rooms early in a run to spawn a Planetarium, and then get the skipped Treasure Room items during the Ascent. However, there's no need to keep doing it after encountering a Planetarium, since the probability to encounter it will stay at 1%.
      • With this strat, you can also open Treasure Rooms doors during the descent, witout getting in it, so you don't have to keep keys for opening them during the Ascent.
  • Devil Rooms or Angel Rooms will have different contents than on the original path.
    • Since the boss rooms have already been cleared during descent, Devil Rooms and Angel Rooms won't open during the Ascent, and can only be accessed with teleport effects.
    • The special Angel Room Shops generated by 15►The Stairway The Stairway will also have different contents.
  • During the Ascent, both items in a double item Treasure Room are visible.
  • Items and trinkets that activate on entering the floor, such as Maggy's Faith Maggy's Faith, will trigger each time Isaac ascends a floor.
  • If attempting to produce a Cracked Key Cracked Key, Myosotis Myosotis should be avoided before successfully leaving a floor with a trinket placed in a Boss or Treasure Room. The effect can move trinkets from previous floors into the starting room of the next floor.
    • Myosotis Myosotis will work on the Ascent, and can be used to bring an additional pickup if holding a Cracked Key Cracked Key.
  • 15►Satanic Bible Satanic Bible has some altered effects during the Ascent.
    • If a boss item became a Devil Deal on the way down and it was not taken, the same item will still be there on the way up but will now cost money instead of heart containers.
    • If used during the Ascent, boss rooms that have already given normal pedestal item drops will contain Devil Deals regardless.
  • In each floor, after exploring all normal rooms, using 15►Teleport 2.0 Teleport 2.0 will teleport Isaac to the Angel/Devil Room, since Secret Rooms and Ultra Secret Rooms will not spawn.
  • If a floor is restarted, which can be accomplished through using 15►Forget Me Now Forget Me Now or by finding a Red 5-pip Dice Room, the following effects will happen:
    • No dream animations will be shown when restarting.
    • The regenerated floor will still be a Ascent floor, not a descent floor.
    • If the floor was an XL one, the regenerated floor will also be XL.
    • If the Treasure Room was skipped during descent, and during the Ascent its contents were seen, after restarting it will contain different items.
    • All Cracked Key Cracked Key in either the Boss Room or the Treasure Room will remain there, even if they were used before restarting.
  • The I AM ERROR room can be reached during the ascent. I AM ERROR rooms will mimic the layout that they had corresponding to the floor. Rather than containing a trapdoor, they will contain a beam of light leading to the next map in the sequence.
  • Entering an I AM ERROR room in Gehenna II (before the Ascent) takes you to Womb II.
  • No consumable voice lines will be spoken during the Ascent.
  • Jacob and Esau Jacob and Esau will overlap one other when ascending to a new floor. This effect stops upon pressing the Swap key or entering a new room.
  • During the descent, it is recomended to left any abandoned Trinket in Treasure Rooms or Boss Rooms, so you can have a maximum of Cracked Key Cracked Key during the Ascent, which means exploring more rooms and eventually found more rewards.
    • You can also leave a maximum of other consumables during the Descent, and then use them during the ascent.

Dialogue[]

At various points during the Ascent, arguments between Isaac's parents can be heard, shedding some light on the fractured state of Isaac's family.

Stage Dialogue Audio
At the start of Mausoleum Mausoleum II
  • Dad: "I spent it. It's gone. Just get over it!"
  • Mom: "What do you mean? What do you mean it's gone? How could you have spent our savings?"
At the start of Depths Depths I / Mines Mines II
  • Mom: "He's self-destructive and disturbed, just like his father! Look at who he has to look up to! ...And you're drunk again, aren't you?"
  • Dad: "SHUT UP, MAGGY! SHUT! UP! You just keep pushing me like this, I'm leaving!"
  • Mom: "Good! LEAVE! We'll be fine without you! Abandon us like you've abandoned yourself..."
At the start of Caves Caves I / Downpour Downpour II
  • Mom: "You need to repent. You need to confess your sins, and become saved! Let His light inside you! CLEANSE YOUR SOU-"
  • Dad: "YOU. ARE. INSANE. You are taking this too far! Can't you hear how you sound!?"
  • Mom: "Pray with me... pray for your salvation! Come, pray with us, Isaac..."
At the start of Basement Basement I
  • (The sound of a door opening and footsteps are heard)
  • Mom: "Where are you going? Wait! We need you! Your son, NEEDS you!"
  • Dad: "I'm doing more harm than good. I just can't do this anymore. I'm sorry."
  • Mom: "Please...! Please don't leave us!"
  • Dad: "I'm sorry, Isaac..."

Trivia[]

  • Great Gideon can be seen during the Ascent. However, since he was already defeated on the way down, he will be deactivated.
    • Even if he was encountered in the Ashpit Ashpit during the normal descent, he will still appear in the Mines Mines during the Ascent.
  • What sounds like a reversed version of Genesis Retake Light can be heard playing during the Ascent, and as the ascent progresses, more instruments are added to it based on the floors the player ascends through.
    • Mausoleum Mausoleum adds a crunchy, electric bass line.
    • Depths Depths adds occasional guitar riffs and a unique composition.
    • Mines Mines adds a drum line and metal clanking sounds.
    • Caves Caves adds a standard bass line.
    • Downpour Downpour adds a fuller guitar line with an echo effect.
    • Basement Basement adds a full percussion line with a standard drum set.

Bugs[]

Bug Bug! If the player enters the Crawl Space left behind by Chaos Carding Great Gideon during the ascent, the game will crash.
Bug Bug! During this sequence, quitting and reloading may lead to the character changing (i.e. changing from Tainted Lazarus to Isaac).
Bug Bug! Crawlspaces that should contain a Black Market instead always lead to the I AM ERROR room.


SmallIsaac.pngChaptersSmallIsaac.png
Chapter 1 Chapter 2 Chapter 3 Chapter 4 Optional Chapter 5 Chapter 6 Endgame
Normal and hard modes only Stage Basement icon.png Stage Caves icon.png Stage Depths icon.png Stage Womb icon.png Stage Sheol icon.png
Sheol


Stage Cathedral icon.png
Cathedral
Stage Dark Room icon.png
Dark Room


Stage Chest icon.png
The Chest
The Basement The Caves The Depths The Womb
Added in Afterbirth Added in Afterbirth †
Stage Cellar icon.png Stage Catacombs icon.png Stage Necropolis icon.png Stage Utero icon.png ??? Stage The Void icon.png
The Cellar The Catacombs Necropolis Utero ??? The Void
Added in Afterbirth Added in Afterbirth Added in Afterbirth Added in Afterbirth
Stage Burning Basement icon.png Stage Flooded Caves icon.png Stage Dank Depths icon.png Stage Scarred Womb icon.png
Burning Basement Flooded Caves Dank Depths Scarred Womb
Added in Repentance Added in Repentance Added in Repentance Added in Repentance Added in Repentance
Stage Downpour.png Stage Mines icon.png Stage Mausoleum icon.png Stage Corpse icon.png Stage Home icon.png
Downpour Mines Mausoleum Corpse Home
Added in Repentance Added in Repentance Added in Repentance
Stage Dross icon.png Stage Ashpit icon.png Stage Gehenna icon.png
Dross Ashpit Gehenna
Added in Afterbirth
Greed and greedier modes only
Added in Afterbirth Added in Afterbirth
Stage Basement icon.png Stage Caves icon.png Stage Depths icon.png Stage Womb icon.png Stage Sheol icon.png The Shop Ultra Greed
The Basement The Caves The Depths The Womb Sheol The Shop Ultra Greed
The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth
Achievements Achievements Attributes Attributes Bosses Bosses TarotCard.png Cards and Runes Challenges Challenges Chapters Chapters
Characters Characters MainPageBabies.png Co-op Items Items Item pools Item pools Monsters Monsters Objects Objects
Pickups Pickups Pills Pills Rooms Rooms Seeds Seeds Transformations Transformations Trinkets Trinkets