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This article is about the item pool. For the room, see Angel Room.



Items in this pool can be found in the Angel RoomAngel Room.

Activated Collectibles[ | ]

Name ID Icon Weight Description
The Bible 5.100.33
The Bible
4 rooms
1
On use, Isaac gains flight for the current room. Instantly kills Boss Mom ingameMom, Boss Mom's Heart ingameMom's Heart, and Boss It Lives ingameIt Lives when activated, but kills Isaac when used on Boss Satan ingameSatan.
Breath of Life 5.100.326
Breath of Life
3 seconds
1
Grants a brief moment of invincibility when the charge bar hits zero. Isaac begins taking damage if the item is held any longer. (in Repentance) Isaac creates beams of light when touching enemies while invulnerable, and creates a powerful 4-way beam if blocking damage exactly as the invincibility starts.
Dead Sea Scrolls 5.100.124
Dead Sea Scrolls
2 rooms
1
Triggers the effect of a random activated item from a list of possible options (not every activated item is included).
Prayer Card 5.100.146
Prayer Card
6 rooms
1
Gives an Eternal HeartEternal Heart per use.
(in Afterbirth † and Repentance) Eden's Soul 5.100.490
Eden's Soul
12 rooms
1
Spawns two item pedestals then is consumed. Begins with no charges.
(in Afterbirth † and Repentance) Void 5.100.477
Void
6 rooms
(except in Repentance)1
(in Repentance)0.5
Consumes all pedestal items in the room. Active items will have their effects added to Void, and passive items will grant random stat upgrades.
(in Afterbirth † and Repentance) Delirious 5.100.510
Delirious
12 rooms
0.4
Spawns Boss Delirium ingameDelirium as a random friendly boss that fights for Isaac.
(in Repentance) Book of Revelations 5.100.78
Book of Revelations
6 rooms
1
Increases the chance of a Devil RoomDevil Room / Angel RoomAngel Room appearing while held. On use, gives one Soul HeartSoul Heart, and replaces the boss of the current floor with a Harbinger if possible.
(in Repentance) Genesis 5.100.622
Genesis
One time use
1
Removes all of Isaac's items and pickups and takes him to a unique Bedroom with some pickups and ChestChests and a trapdoor to the next floor. For every item Isaac lost, he gets to take an item from a set of three.
(in Repentance) Jar of Wisps 5.100.685
Jar of Wisps
12 rooms
1
Spawns random wisps that shoot various tears, block shots, and deal contact damage. The number of wisps spawned increases every time the jar is used.
(in Repentance) Urn of Souls 5.100.640
Urn of Souls
Unlimited
1
Spews a stream of damaging flame. Gains Soul Charges each time an enemy dies, which are used to fuel the urn.
(in Repentance) Vade Retro 5.100.653
Vade Retro
Unlimited
1
While held, enemies leave behind ghosts on death. Stronger enemies leave bigger ghosts. Using the item causes the ghosts to explode and damage nearby enemies, and instantly kills all ghost enemies with less than 50% HP.

Passive Collectibles[ | ]

Name ID Icon Weight Description
The Body 5.100.334 The Body
1
Adds 3 Red Heart Containers.
Celtic Cross 5.100.162 Celtic Cross
1
Grants a chance to trigger the Collectible Book of Shadows iconBook of Shadows effect upon taking damage, creating a shield that nullifies all types of damage for 7 seconds.
Dead Dove 5.100.185 Dead Dove
1
Grants spectral tears and flight.
Godhead 5.100.331 Godhead
1
(except in Repentance) Grants homing tears with a damaging halo. +0.5 Damage, -0.3 Tears -0.3 Shot Speed, +0.8 Tear Falling Speed, and +1.2 Range.
(in Repentance) Grants homing tears with a damaging halo. +0.5 Damage, -0.3 Tears, and -0.3 Shot Speed.
Guardian Angel 5.100.112 Guardian Angel
1
Spawns an orbital familiar that blocks enemy shots, deals (except in Repentance) 105 /(in Repentance) 52.5 damage per second to enemies, and increases the speed of all orbital familiars.
Habit 5.100.156 Habit
1
When Isaac is hit, his active item gains 1 room's worth of charge.
The Halo 5.100.101 The Halo
1
(except in Repentance) Grants one full Red Heart container, +0.3 damage, +0.2 tears, +0.25 range, +0.3 speed, and +0.5 tear falling speed.
(in Repentance) Grants one full Red Heart container, +0.3 damage, +0.2 tears, +1.5 range, and +0.3 speed. Heals 1 additional Red HeartRed Heart.
Holy Grail 5.100.184 Holy Grail
1
Grants flight and one Red Heart container. (in Repentance) Heals 1 additional Red HeartRed Heart.
Holy Mantle 5.100.313 Holy Mantle
1
Grants a shield that negates the first instance of damage taken, once per room. Does not apply to or negate self-damage (Blood Donation MachineBlood Donation Machines, etc).
Holy Water 5.100.178 Holy Water
1
(except in Repentance) Spawns a bottle familiar that breaks when Isaac takes damage, leaving a puddle of blue creep.
(in Repentance) A bottle familiar that flies forward when Isaac shoots. It breaks upon hitting an enemy, leaving a puddle of blue creep that petrifies enemies.
Lazarus' Rags 5.100.332 Lazarus' Rags
1
(except in Repentance) Upon dying, resurrect as Character Lazarus Risen iconLazarus Risen in the current room with one Red Heart container and Collectible Anemic iconAnemic.
(in Repentance) Upon dying, resurrect as Character Lazarus Risen iconLazarus Risen in the current room with one less Red Heart container, Collectible Anemic iconAnemic, and +0.5 Damage. Transform into Character Lazarus iconLazarus when reaching the next floor.
The Mind 5.100.333 The Mind
1
Reveals the entire map, including all special rooms and Secret RoomSecret Rooms.
Mitre 5.100.173 Mitre
1
Grants a chance of converting any Red HeartRed Heart pickups into Soul HeartSoul Hearts instead.
The Relic 5.100.98 The Relic
1
Spawns a cross familiar that drops a Soul HeartSoul Heart after clearing enough rooms.
Rosary 5.100.72 Rosary
1
Grants 3 Soul HeartSoul Hearts. Causes Collectible The Bible iconThe Bible to appear in any item pool. (in Repentance) +0.5 tears.
Sacred Heart 5.100.182 Sacred Heart
1
(except in Repentance) Adds a Red Heart Container. Grants homing tears, a x2.3 Damage multiplier, +1 flat Damage, -0.4 Tears, -0.25 Shot Speed, and +4.125 Range.
(in Repentance) Adds a Red Heart Container. Grants homing tears, a x2.3 Damage multiplier, +1 flat Damage, -0.4 Tears, and -0.25 Shot Speed.
Scapular 5.100.142 Scapular
1
Once per room, when Isaac is reduced to his last half heart, he is granted one Soul HeartSoul Heart.
The Soul 5.100.335 The Soul
1
Grants two Soul HeartSoul Hearts. Isaac gains a pulsing aura that repels enemies and projectiles.
Trinity Shield 5.100.243 Trinity Shield
1
Isaac gains a shield that protects him from enemy shots. It aims in the direction Isaac fires from.
The Wafer 5.100.108 The Wafer
1
Most sources of damage that would cause more than one-half heart of damage are reduced to one-half heart instead.
(except in Rebirth) Censer 5.100.387 Censer
1
Spawns a familiar which creates a circular aura that slows down enemies and enemy shots inside.
(except in Rebirth) Circle of Protection 5.100.423 Circle of Protection
1
Surrounds Isaac with a large white halo that occasionally deals Isaac's tear damage to enemies inside it, and can convert enemy shots into friendly homing tears.
(except in Rebirth) Crown of Light 5.100.415 Crown of Light
1
+2 Soul HeartSoul Hearts. While Isaac has no empty red hearts, grants 2x damage, increased range, and -0.3 shot speed. Regardless of health, the crown deactivates for the current room when Isaac takes damage.
(except in Rebirth) Holy Light 5.100.374 Holy Light
1
Adds a chance to fire holy tears, which will create a damaging light beam in the area if they hit an enemy.
(except in Rebirth) Immaculate Conception 5.100.413 Immaculate Conception
1
Upon picking up a certain amount of health, spawn a permanent angelic familiar.
(except in Rebirth) Purity 5.100.407 Purity
1
Boosts one of Isaac's stats depending on the color of the aura around him. The aura disappears upon taking damage and reappears with a random color upon entering a new room. Red boosts damage, blue boosts tears, yellow boosts speed, and orange boosts range.
(except in Rebirth) Seraphim 5.100.390 Seraphim
1
Spawns an angel familiar who follows Isaac and fires homing tears which deal 10 damage and have 75% shot speed.
(except in Rebirth) Spear of Destiny 5.100.400 Spear of Destiny
1
In addition to tears, Isaac holds a spear in front of him which deals contact damage equal to 2x his tear damage, and occasionally inflicts fear.
(except in Rebirth) Sworn Protector 5.100.363 Sworn Protector
1
Spawns an orbital familiar which does 105 damage per second and attracts and blocks enemy shots. Upon blocking 10 shots in a room, it drops an Eternal HeartEternal Heart.
(in Afterbirth † and Repentance) 7 Seals 5.100.526 7 Seals
1
Spawns a random Harbinger familiar that changes every 10 seconds. Harbingers have different behaviors and spawn themed Locusts.
(in Afterbirth † and Repentance) Angelic Prism 5.100.528 Angelic Prism
1
Spawns an orbital familiar with a large orbital radius. Tears that pass through the prism split into four multi-colored tears.
(in Afterbirth † and Repentance) Duality 5.100.498 Duality
1
Whenever a Devil RoomDevil Room or Angel RoomAngel Room would spawn after defeating a boss, both rooms spawn. Only one can be entered.
(in Afterbirth † and Repentance) Eucharist 5.100.499 Eucharist
1
An Angel RoomAngel Room door will always spawn after every boss fight, excluding the first floor and floors after WombWomb II/UteroUtero II/Scarred WombScarred Womb II.
(in Afterbirth † and Repentance) Glyph of Balance 5.100.464 Glyph of Balance
1
Grants 2 Soul HeartSoul Hearts and modifies drops from Champion monsters based on certain conditions. (in Repentance) Also modifies room clear drops.
(in Afterbirth † and Repentance) Lil Delirium 5.100.519 Lil Delirium
1
Grants a familiar that transforms into another random familiar every 10 seconds.
(in Afterbirth † and Repentance) Trisagion 5.100.533 Trisagion
1
Tears are replaced with piercing white blasts of light that deal less damage but can damage the same enemy multiple times.
(in Repentance) Act of Contrition 5.100.601 Act of Contrition
1
Increases tears and grants an Eternal HeartEternal Heart. Allows Angel RoomAngel Rooms to appear even if a Devil Deal has been taken before. Reduces the Devil/Angel room chance penalty for taking Red heart damage.
(in Repentance) Blood of the Martyr 5.100.7 Blood of the Martyr
1
+1 damage. Isaac shoots blood tears.
(in Repentance) Divine Intervention 5.100.568 Divine Intervention
1
Double tapping a fire key creates a shield that pushes away enemies and reflects enemy projectiles and lasers.
(in Repentance) Hallowed Ground 5.100.543 Hallowed Ground
1
Spawns a white poop familiar, which turns into a White PoopWhite Poop when Isaac is hurt. White poop has an aura that increases tear fire rate and can block enemy shots. (in Repentance) The aura also increases damage by 20% and gives homing.
(in Repentance) Immaculate Heart 5.100.573 Immaculate Heart
1
Adds one Red Heart Container and fully restores health. x1.2 damage multiplier. Isaac will occasionally fire extra tears that orbit around him.
(in Repentance) Jesus Juice 5.100.197 Jesus Juice
1
(except in Repentance) +0.5 damage, +0.25 range, +0.5 tear falling speed.
(in Repentance) +0.5 damage, +1.5 range.
(in Repentance) Monstrance 5.100.574 Monstrance
1
Isaac gains an aura that deals damage to enemies inside it.
(in Repentance) Paschal Candle 5.100.567 Paschal Candle
1
Gives Isaac a familiar that grants +0.4 Fire Rate for each consecutive room he's cleared without taking damage. The bonus stacks up to five times.
(in Repentance) Purgatory 5.100.634 Purgatory
1
While in a room with enemies, spawns cracks on the ground. Walking over these cracks summons ghosts that launch themselves at enemies and explode.
(in Repentance) Revelation 5.100.643 Revelation
1
Grants flight and two Soul HeartSoul Hearts. In addition to tears, Isaac can charge up and fire a powerful holy laser.
(in Repentance) Salvation 5.100.696 Salvation
1
Gives Isaac a halo that summons beams of light on enemies inside it. The halo grows larger the more times Isaac has taken damage this floor.
(in Repentance) Spirit Sword 5.100.579 Spirit Sword
1
Instead of tears, Isaac swings a sword. Charging does a spin attack and fires a projectile, and a projectile is sometimes fired with normal swings if Isaac has no empty Red HeartRed Heart Containers.
(in Repentance) Star of Bethlehem 5.100.651 Star of Bethlehem
1
Spawns a star familiar that slowly travels towards the Boss RoomBoss Room, giving an aura that increases damage and tears and grants homing tears.
(in Repentance) Stigmata 5.100.138 Stigmata
1
+0.3 damage, grants one full Red Heart container. (in Repentance) Heals 1 additional Red HeartRed Heart.
(in Repentance) Soul Locket 5.100.686 Soul Locket
1
Gives Isaac a permanent stat boost whenever he picks up a Soul HeartSoul Heart.
(in Repentance) The Stairway 5.100.586 The Stairway
1
Generates a ladder at the start of every floor that leads to a unique Angel RoomAngel Room shop.
(in Repentance) Book of Virtues 5.100.584
Book of Virtues
4 rooms
0.5
On use, spawns a destroyable orbiting wisp familiar that fires tears and deals contact damage. Also acts as a passive item that causes other active items to spawn themed wisps.
(in Repentance) Sacred Orb 5.100.691 Sacred Orb
0.5
Prevents items of quality 0-1 from appearing, and items of quality 2 from appearing 33% of the time, greatly increasing the quality of items received from all item pools. Quest items are unaffected.


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