Binding of Isaac: Rebirth Wiki
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Binding of Isaac: Rebirth Wiki
Added in Afterbirth

Items in this pool can be found in the Angel Room in Greed mode.

Activated Collectibles[]

Name ID Icon Weight Description
Book of Revelations 5.100.78
Book of Revelations
6 rooms
1
Gives one Soul Heart, increases the chance for a Devil Room Devil Room or Angel Room Angel Room, and changes the boss of the current floor to a Harbinger if possible.
Added in Afterbirth † Eden's Soul 5.100.490
Eden's Soul
12 rooms
1
Spawns two item pedestals then is consumed. Begins with no charges.
Added in Repentance Genesis 5.100.622
Genesis
One time use
1
Removes all of Isaac's items and pickups and takes him to a unique Bedroom with some pickups and Chests and a trapdoor to the next floor. For every item Isaac lost, he gets to take an item from a set of three.
Added in Repentance Jar of Wisps 5.100.685
Jar of Wisps
12 rooms
1
Spawns random wisps that shoot various tears, block shots, and deal contact damage. The number of wisps spawned increases every time the jar is used.
Added in Repentance Urn of Souls 5.100.640
Urn of Souls
Unlimited
1
Spews a stream of damaging flame. Gains Soul Charges each time an enemy dies, which are used to fuel the urn.
Added in Repentance Vade Retro 5.100.653
Vade Retro
Unlimited
1
While held, enemies leave behind ghosts on death. Using the item causes the ghosts to explode, dealing damage to nearby enemies. Stronger enemies leave bigger ghosts.
Added in Repentance Book of Virtues 5.100.584
Book of Virtues
4 rooms
0.5
On use, spawns a destroyable orbiting Wisp familiar that fires tears and deals contact damage. Also acts as a passive item that causes other active items to spawn themed Wisps.

Passive Collectibles[]

Name ID Icon Weight Description
Blood of the Martyr 5.100.7 Blood of the Martyr
1
Increases damage by 1, and turns Isaac's tears into blood tears.
The Body 5.100.334 The Body
1
Adds 3 Red Heart Containers.
Celtic Cross 5.100.162 Celtic Cross
1
Grants a chance to trigger the 15►Book of Shadows Book of Shadows effect upon taking damage, creating a shield that nullifies all types of damage for 7 seconds.
Censer 5.100.387 Censer
1
Spawns a familiar which creates a circular aura that slows down enemies and enemy shots inside.
Circle of Protection 5.100.423 Circle of Protection
1
Surrounds Isaac with a large white halo that occasionally deals Isaac's tear damage to enemies inside it, and can convert enemy shots into friendly homing tears.
Crown of Light 5.100.415 Crown of Light
1
+2 soul hearts. While Isaac has no empty red hearts, grants 2x damage, +5.25 range, and -0.3 shot speed. Regardless of health, the crown deactivates for the current room when Isaac takes damage.
Cube of Meat 5.100.73 Cube of Meat
1
Spawns an orbital familiar that blocks enemy shots, dealing 105 damage per second. Collecting additional copies grants it the ability to shoot, then chase enemies, then increases the damage.
Dead Dove 5.100.185 Dead Dove
1
Grants spectral tears and flight.
Godhead 5.100.331 Godhead
1
Grants homing tears with a damaging halo. +0.5 damage, -0.3 tears, +1.2 range, -0.3 shot speed, +0.8 tear height.
Guardian Angel 5.100.112 Guardian Angel
1
Spawns an orbital familiar that blocks enemy shots, deals 105 damage per second to enemies, and increases the speed of all orbital familiars.
Holy Grail 5.100.184 Holy Grail
1
Grants flight and one Red Heart container.
Holy Mantle 5.100.313 Holy Mantle
1
Upon entering a room, grants a shield that negates the first damage taken.
Holy Water 5.100.178 Holy Water
1
Removed in Repentance Spawns a bottle familiar that breaks when Isaac takes damage, leaving a puddle of blue creep.
Added in Repentance A bottle familiar that flies forward when Isaac shoots. It breaks upon hitting an enemy, leaving a puddle of blue creep that petrifies enemies.
Immaculate Conception 5.100.413 Immaculate Conception
1
Upon picking up a certain amount of health, spawn a permanent angelic familiar.
Jesus Juice 5.100.197 Jesus Juice
1
+0.5 damage, +0.25 range, +0.5 tear height.
The Mind 5.100.333 The Mind
1
Reveals the entire map, including all special rooms and Secret Rooms.
Mitre 5.100.173 Mitre
1
Grants a chance of converting any Red Heart pickups into Soul Hearts instead.
Purity 5.100.407 Purity
1
Boosts one of Isaac's stats depending on the color of the aura around him. The aura disappears upon taking damage and reappears with a random color upon entering a new room. Red boosts damage, blue boosts tears, yellow boosts speed, and orange boosts range.
Rosary 5.100.72 Rosary
1
Adds 3 Soul Hearts. The Bible will appear in any item pool.
Added in RepentanceAlso a +0.5 tears up.
Sacred Heart 5.100.182 Sacred Heart
1
Grants homing tears, x2.3 damage multiplier, +1 flat damage, +4.125 range, +0.75 tear height, -0.4 tears, -0.25 shot speed, a red Heart Container and replenishes all Red Hearts.
Seraphim 5.100.390 Seraphim
1
Spawns an angel familiar which follows Isaac and fires homing tears which deal 10 damage and have 75% shot speed.
Spear of Destiny 5.100.400 Spear of Destiny
1
In addition to tears, Isaac holds a spear in front of him which deals contact damage equal to 2x his tear damage, and occasionally inflicts fear.
Stigmata 5.100.138 Stigmata
1
Increases damage, and adds 1 heart container.
Sworn Protector 5.100.363 Sworn Protector
1
Spawns an orbital familiar which does 105 damage per second and attracts and blocks enemy shots. Upon blocking 10 shots in a room, it drops an Eternal Heart.
The Soul 5.100.335 The Soul
1
Grants two Soul Hearts. Isaac gains a pulsing aura that repels enemies and projectiles.
Trinity Shield 5.100.243 Trinity Shield
1
Isaac gains a shield that protects him from enemy shots. It aims in the direction Isaac fires from.
Added in Afterbirth † 7 Seals 5.100.526 7 Seals
1
Spawns a random Harbinger familiar that changes every 10 seconds. Harbingers have different behaviors and spawn themed Locusts.
Added in Afterbirth † Angelic Prism 5.100.528 Angelic Prism
1
Spawns an orbital familiar with a large orbital radius. Tears that pass through the prism split into four multi-colored tears.
Added in Afterbirth † Eucharist 5.100.499 Eucharist
1
An Angel Room door will always spawn after every boss fight, excluding the first floor and floors after Womb Womb II/Utero Utero II/.
Added in Afterbirth † Glyph of Balance 5.100.464 Glyph of Balance
1
Grants 2 Soul Hearts and modifies drops from Champion monsters based on certain conditions. Added in Repentance Also modifies room clear drops.
Added in Afterbirth † Trisagion 5.100.533 Trisagion
1
Damage down. Tears are replaced with piercing white blasts of light that can damage the same enemy multiple times.
Added in Repentance Act of Contrition 5.100.601 Act of Contrition
1
Increases tears and grants an Eternal Heart. Allows Angel Rooms to appear even if a Devil deal has been taken before. Greatly boosts Devil/Angel Deal chance if Isaac has taken Red Heart damage.
Added in Repentance Divine Intervention 5.100.568 Divine Intervention
1
Double tapping a fire key creates a shield that pushes away enemies and reflects enemy projectiles and lasers.
Added in Repentance Immaculate Heart 5.100.573 Immaculate Heart
1
Adds one Red Heart Container and fully restores health. x1.2 damage multiplier. Isaac will occasionally fire extra tears that orbit around him.
Added in Repentance Monstrance 5.100.574 Monstrance
1
Isaac gains an aura that deals damage to enemies inside it.
Added in Repentance Paschal Candle 5.100.567 Paschal Candle
1
Gives Isaac a candle familiar that grants a Tears bonus of +0.4 for each room cleared in a row without taking damage, which stacks up to 5 times, represented by how brightly the flame burns. Starts at 1 stack, and resets to zero if damage is taken.
Added in Repentance Purgatory 5.100.634 Purgatory
1
While in a room with enemies, spawns cracks on the ground. Walking over these cracks summons ghosts that launch themselves at enemies and explode.
Added in Repentance Revelation 5.100.643 Revelation
1
Grants flight and two soul hearts. In addition to tears, Isaac can charge up and fire a powerful holy laser.
Added in Repentance Salvation 5.100.696 Salvation
1
Gives Isaac a halo that summons beams of light on enemies inside it. The halo grows larger the more times Isaac has taken damage this floor.
Added in Repentance Soul Locket 5.100.686 Soul Locket
1
Gives Isaac a permanent stat boost whenever he picks up a soul heart.
Added in Repentance Spirit Sword 5.100.579 Spirit Sword
1
Instead of tears, Isaac swings a sword. Charging does a spin attack and fires a projectile, and a projectile is sometimes fired with normal swings if Isaac has no empty red hearts.
Added in Repentance The Stairway 5.100.586 The Stairway
1
Generates a ladder at the start of every floor that leads to a unique Angel Room shop.
Added in Repentance Star of Bethlehem 5.100.651 Star of Bethlehem
1
Spawns a star familiar that slowly travels towards the Boss Room, giving an aura that increases damage and tears and grants homing tears.
Added in Repentance Sacred Orb 5.100.691 Sacred Orb
0.5
Prevents low-quality items from spawning, greatly increasing the quality of items received from all item pools.


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