Binding of Isaac: Rebirth Wiki
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(except in Rebirth)

Items in this pool can be found in the Angel RoomAngel Room in Greed mode.

Activated Collectibles[ | ]

Name ID Icon Weight Description
Book of Revelations 5.100.78
Book of Revelations
6 rooms
1
Increases the chance of a Devil RoomDevil Room / Angel RoomAngel Room appearing while held. On use, gives one Soul HeartSoul Heart, and replaces the boss of the current floor with a Harbinger if possible.
(in Afterbirth † and Repentance) Eden's Soul 5.100.490
Eden's Soul
12 rooms
1
Spawns two item pedestals then is consumed. Begins with no charges.
(in Repentance) Breath of Life 5.100.326
Breath of Life
3 seconds
1
Grants a brief moment of invincibility when the charge bar hits zero. Isaac begins taking damage if the item is held any longer. (in Repentance) Isaac creates beams of light when touching enemies while invulnerable, and creates a powerful 4-way beam if blocking damage exactly as the invincibility starts.
(in Repentance) Genesis 5.100.622
Genesis
One time use
1
Removes all of Isaac's items and pickups and takes him to a unique Bedroom with some pickups and ChestChests and a trapdoor to the next floor. For every item Isaac lost, he gets to take an item from a set of three.
(in Repentance) Jar of Wisps 5.100.685
Jar of Wisps
12 rooms
1
Spawns random wisps that shoot various tears, block shots, and deal contact damage. The number of wisps spawned increases every time the jar is used.
(in Repentance) Urn of Souls 5.100.640
Urn of Souls
Unlimited
1
Spews a stream of damaging flame. Gains Soul Charges each time an enemy dies, which are used to fuel the urn.
(in Repentance) Vade Retro 5.100.653
Vade Retro
Unlimited
1
While held, enemies leave behind ghosts on death. Stronger enemies leave bigger ghosts. Using the item causes the ghosts to explode and damage nearby enemies, and instantly kills all ghost enemies with less than 50% HP.

Passive Collectibles[ | ]

Name ID Icon Weight Description
Blood of the Martyr 5.100.7 Blood of the Martyr
1
+1 damage. Isaac shoots blood tears.
The Body 5.100.334 The Body
1
Adds 3 Red Heart Containers.
Celtic Cross 5.100.162 Celtic Cross
1
Grants a chance to trigger the Collectible Book of Shadows iconBook of Shadows effect upon taking damage, creating a shield that nullifies all types of damage for 7 seconds.
Censer 5.100.387 Censer
1
Spawns a familiar which creates a circular aura that slows down enemies and enemy shots inside.
Circle of Protection 5.100.423 Circle of Protection
1
Surrounds Isaac with a large white halo that occasionally deals Isaac's tear damage to enemies inside it, and can convert enemy shots into friendly homing tears.
Crown Of Light 5.100.415 Crown Of Light
1
+2 Soul HeartSoul Hearts. While Isaac has no empty red hearts, grants 2x damage, increased range, and -0.3 shot speed. Regardless of health, the crown deactivates for the current room when Isaac takes damage.
Dead Dove 5.100.185 Dead Dove
1
Grants spectral tears and flight.
Godhead 5.100.331 Godhead
1
(except in Repentance) Grants homing tears with a damaging halo. +0.5 Damage, -0.3 Tears -0.3 Shot Speed, +0.8 Tear Falling Speed, and +1.2 Range.
(in Repentance) Grants homing tears with a damaging halo. +0.5 Damage, -0.3 Tears, and -0.3 Shot Speed.
Guardian Angel 5.100.112 Guardian Angel
1
Spawns an orbital familiar that blocks enemy shots, deals (except in Repentance) 105 /(in Repentance) 52.5 damage per second to enemies, and increases the speed of all orbital familiars.
Holy Grail 5.100.184 Holy Grail
1
Grants flight and one Red Heart container. (in Repentance) Heals 1 additional Red HeartRed Heart.
Holy Mantle 5.100.313 Holy Mantle
1
Grants a shield that negates the first instance of damage taken, once per room. Does not apply to or negate self-damage (Blood Donation MachineBlood Donation Machines, etc).
Holy Water 5.100.178 Holy Water
1
(except in Repentance) Spawns a bottle familiar that breaks when Isaac takes damage, leaving a puddle of blue creep.
(in Repentance) A bottle familiar that flies forward when Isaac shoots. It breaks upon hitting an enemy, leaving a puddle of blue creep that petrifies enemies.
Immaculate Conception 5.100.413 Immaculate Conception
1
Upon picking up a certain amount of health, spawn a permanent angelic familiar.
Jesus Juice 5.100.197 Jesus Juice
1
(except in Repentance) +0.5 damage, +0.25 range, +0.5 tear falling speed.
(in Repentance) +0.5 damage, +1.5 range.
The Mind 5.100.333 The Mind
1
Reveals the entire map, including all special rooms and Secret RoomSecret Rooms.
Purity 5.100.407 Purity
1
Boosts one of Isaac's stats depending on the color of the aura around him. The aura disappears upon taking damage and reappears with a random color upon entering a new room. Red boosts damage, blue boosts tears, yellow boosts speed, and orange boosts range.
Rosary 5.100.72 Rosary
1
Grants 3 Soul HeartSoul Hearts. Causes Collectible The Bible iconThe Bible to appear in any item pool. (in Repentance) +0.5 tears.
Sacred Heart 5.100.182 Sacred Heart
1
(except in Repentance) Adds a Red Heart Container. Grants homing tears, a x2.3 Damage multiplier, +1 flat Damage, -0.4 Tears, -0.25 Shot Speed, and +4.125 Range.
(in Repentance) Adds a Red Heart Container. Grants homing tears, a x2.3 Damage multiplier, +1 flat Damage, -0.4 Tears, and -0.25 Shot Speed.
Seraphim 5.100.390 Seraphim
1
Spawns an angel familiar who follows Isaac and fires homing tears which deal 10 damage and have 75% shot speed.
The Soul 5.100.335 The Soul
1
Grants two Soul HeartSoul Hearts. Isaac gains a pulsing aura that repels enemies and projectiles.
Spear Of Destiny 5.100.400 Spear Of Destiny
1
In addition to tears, Isaac holds a spear in front of him which deals contact damage equal to 2x his tear damage, and occasionally inflicts fear.
Stigmata 5.100.138 Stigmata
1
+0.3 damage, grants one full Red Heart container. (in Repentance) Heals 1 additional Red HeartRed Heart.
Sworn Protector 5.100.363 Sworn Protector
1
Spawns an orbital familiar which does 105 damage per second and attracts and blocks enemy shots. Upon blocking 10 shots in a room, it drops an Eternal HeartEternal Heart.
Trinity Shield 5.100.243 Trinity Shield
1
Isaac gains a shield that protects him from enemy shots. It aims in the direction Isaac fires from.
(except in Repentance) Cube of Meat 5.100.73 Cube of Meat
1
Creates an orbital familiar. Collecting additional copies gives it the ability to shoot tears, then chase enemies to deal contact damage, then deal even more contact damage.
(except in Repentance) Mitre 5.100.173 Mitre
1
Grants a chance of converting any Red HeartRed Heart pickups into Soul HeartSoul Hearts instead.
(in Afterbirth † and Repentance) 7 Seals 5.100.526 7 Seals
1
Spawns a random Harbinger familiar that changes every 10 seconds. Harbingers have different behaviors and spawn themed Locusts.
(in Afterbirth † and Repentance) Angelic Prism 5.100.528 Angelic Prism
1
Spawns an orbital familiar with a large orbital radius. Tears that pass through the prism split into four multi-colored tears.
(in Afterbirth † and Repentance) Eucharist 5.100.499 Eucharist
1
An Angel RoomAngel Room door will always spawn after every boss fight, excluding the first floor and floors after WombWomb II/UteroUtero II/Scarred WombScarred Womb II.
(in Afterbirth † and Repentance) Trisagion 5.100.533 Trisagion
1
Tears are replaced with piercing white blasts of light that deal less damage but can damage the same enemy multiple times.
(in Afterbirth †) Glyph of Balance 5.100.464 Glyph of Balance
1
Grants 2 Soul HeartSoul Hearts and modifies drops from Champion monsters based on certain conditions. (in Repentance) Also modifies room clear drops.
(in Repentance) Act of Contrition 5.100.601 Act of Contrition
1
+0.7 tears, grants an Eternal HeartEternal Heart. Allows Angel RoomAngel Rooms to appear even if a Devil Deal has been taken before. Reduces the Devil/Angel room chance penalty for taking Red heart damage.
(in Repentance) Divine Intervention 5.100.568 Divine Intervention
1
Double tapping a fire key creates a shield that pushes away enemies and reflects enemy projectiles and lasers.
(in Repentance) Hallowed Ground 5.100.543 Hallowed Ground
1
Spawns a white poop familiar, which turns into a White PoopWhite Poop when Isaac is hurt. White poop has an aura that increases tear fire rate and can block enemy shots. (in Repentance) The aura also increases damage by 20% and gives homing.
(in Repentance) Immaculate Heart 5.100.573 Immaculate Heart
1
Adds one Red Heart Container and fully restores health. x1.2 damage multiplier. Isaac will occasionally fire extra tears that orbit around him.
(in Repentance) Monstrance 5.100.574 Monstrance
1
Isaac gains an aura that deals damage to enemies inside it.
(in Repentance) Paschal Candle 5.100.567 Paschal Candle
1
Gives Isaac a familiar that grants +0.4 Fire Rate for each consecutive room he's cleared without taking damage. The bonus stacks up to five times.
(in Repentance) Purgatory 5.100.634 Purgatory
1
While in a room with enemies, spawns cracks on the ground. Walking over these cracks summons ghosts that launch themselves at enemies and explode.
(in Repentance) Revelation 5.100.643 Revelation
1
Grants flight and two Soul HeartSoul Hearts. In addition to tears, Isaac can charge up and fire a powerful holy laser.
(in Repentance) Salvation 5.100.696 Salvation
1
Gives Isaac a halo that summons beams of light on enemies inside it. The halo grows larger the more times Isaac has taken damage this floor.
(in Repentance) Soul Locket 5.100.686 Soul Locket
1
Gives Isaac a permanent stat boost whenever he picks up a Soul HeartSoul Heart.
(in Repentance) Spirit Sword 5.100.579 Spirit Sword
1
Instead of tears, Isaac swings a sword. Charging does a spin attack and fires a projectile, and a projectile is sometimes fired with normal swings if Isaac has no empty Red HeartRed Heart Containers.
(in Repentance) The Stairway 5.100.586 The Stairway
1
Generates a ladder at the start of every floor that leads to a unique Angel RoomAngel Room shop.
(in Repentance) Star of Bethlehem 5.100.651 Star of Bethlehem
1
Spawns a star familiar that slowly travels towards the Boss RoomBoss Room, giving an aura that increases damage and tears and grants homing tears.
(in Repentance) Book of Virtues 5.100.584
Book of Virtues
4 rooms
0.5
On use, spawns a destroyable orbiting wisp familiar that fires tears and deals contact damage. Also acts as a passive item that causes other active items to spawn themed wisps.
(in Repentance) Sacred Orb 5.100.691 Sacred Orb
0.5
Prevents items of quality 0-1 from appearing, and items of quality 2 from appearing 33% of the time, greatly increasing the quality of items received from all item pools. Quest items are unaffected.


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