Binding of Isaac: Rebirth Wiki
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Bosses[ | ]

Boss Monstro
Boss Gemini
Boss Steven
Boss Dingle
Monstro Gemini Steven Needs to be unlocked Dingle
Boss Gurglings
Boss Larry Jr.
Boss The Duke of Flies
Boss Widow
Gurglings Larry Jr. The Duke of Flies Widow
Boss Blighted Ovum
Boss The Haunt
Boss Pin
Boss Famine
Blighted Ovum The Haunt Pin Famine Needs to be unlocked
Boss Fistula
Boss Chub
Boss C.H.A.D.
Boss Gurdy
Fistula Chub C.H.A.D. Needs to be unlocked Gurdy
Boss Mega Fatty
Boss Mega Maw
Boss Gurdy Jr.
Boss Peep
Mega Fatty Mega Maw Gurdy Jr. Peep
Boss The Husk
Boss The Hollow
Boss Carrion Queen
Boss Dark One
The Husk The Hollow Carrion Queen Dark One
Boss Polycephalus
Boss The Wretched
Boss Pestilence
Boss Monstro II
Polycephalus The Wretched Pestilence Needs to be unlocked Monstro II
Boss Gish
Boss The Cage
Boss The Gate
Boss Loki
Gish Needs to be unlocked The Cage The Gate Loki
Boss The Adversary
Boss The Bloat
Boss Mask of Infamy portrait
Boss War
The Adversary The Bloat Mask Of Infamy War Needs to be unlocked
Boss Blastocyst
Boss Mama Gurdy
Boss Scolex
Boss Mr. Fred
Blastocyst Mama Gurdy Scolex Mr. Fred
Boss Lokii
Boss Daddy Long Legs
Boss Triachnid
Boss Teratoma
Lokii Daddy Long Legs Triachnid Needs to be unlocked Teratoma
Boss Death
Boss Conquest
Boss Headless Horseman
Boss The Fallen
Death Needs to be unlocked Conquest Needs to be unlocked Headless Horseman Needs to be unlocked The Fallen Devil Room Icon

Afterbirth (except in Rebirth)[ | ]

Boss Dangle
Boss Turdlings
Boss Little Horn
Boss Rag Man
Dangle Needs to be unlocked Turdlings Needs to be unlocked Little Horn Needs to be unlocked Rag Man Needs to be unlocked
Boss The Stain
Boss The Forsaken
Boss The Frail
Boss Brownie
The Stain Needs to be unlocked The Forsaken Needs to be unlocked The Frail Needs to be unlocked Brownie Needs to be unlocked

Afterbirth+ (in Afterbirth † and Repentance)[ | ]

Boss Big Horn
Boss Rag Mega
Boss Sisters Vis
Boss The Matriarch
Big Horn Needs to be unlocked Rag Mega Needs to be unlocked Sisters Vis Needs to be unlocked The Matriarch Needs to be unlocked

Repentance (in Repentance)[ | ]

Boss Baby Plum
Boss Bumbino
Boss Reap Creep
Boss The Pile
Baby Plum Needs to be unlocked Bumbino Needs to be unlocked Reap Creep Needs to be unlocked The Pile Needs to be unlocked
Boss The Rainmaker
Boss Min-Min
Boss Lil Blub
Boss Wormwood
The Rainmaker Needs to be unlocked Min-Min Needs to be unlocked Lil Blub Needs to be unlocked Wormwood Needs to be unlocked
Boss Clog
Boss Colostomia
Boss Turdlet
Boss Tuff Twins
Clog Needs to be unlocked Colostomia Needs to be unlocked Turdlet Needs to be unlocked Tuff Twins Needs to be unlocked
Boss Hornfel
Boss Great Gideon
Boss Singe
Boss The Shell
Hornfel Needs to be unlocked Great Gideon Needs to be unlocked Singe Needs to be unlocked The Shell Needs to be unlocked
Boss Clutch
Boss The Siren
Boss The Heretic
Boss The Visage
Clutch Needs to be unlocked The Siren Needs to be unlocked The Heretic Needs to be unlocked The Visage Needs to be unlocked
Boss Horny Boys
Boss Chimera
Boss The Scourge
Boss Rotgut
The Horny Boys Needs to be unlocked Chimera Needs to be unlocked The Scourge Needs to be unlocked Rotgut Needs to be unlocked
Boss Ultra Famine ingame
Boss Ultra Pestilence ingame
Ultra War ingame
Ultra Death ingame
Ultra Famine Needs to be unlocked Ultra Pestilence Needs to be unlocked Ultra War Needs to be unlocked Ultra Death Needs to be unlocked

Final Bosses[ | ]

Boss Mom
Boss Mom's Heart
Boss It Lives
Boss Satan
Mom Mom's Heart Needs to be unlocked It Lives Needs to be unlocked Satan Needs to be unlocked
Boss Isaac
Boss The Lamb
???
Boss Mega Satan
Isaac Needs to be unlocked The Lamb Needs to be unlocked ??? Needs to be unlocked Mega Satan Needs to be unlocked
Boss Hush portrait
Boss Delirium
Boss Mother
Boss Dogma
Hush (except in Rebirth) Needs to be unlocked Delirium (in Afterbirth † and Repentance) Needs to be unlocked Mother (in Repentance) Needs to be unlocked Dogma (in Repentance) Needs to be unlocked
The Beast ingame
Boss Ultra Greed
Boss Ultra Greedier
The Beast (in Repentance) Needs to be unlocked Ultra Greed (except in Rebirth) Ultra Greedier (in Afterbirth † and Repentance) Needs to be unlocked

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