All Bosses (Bosses)

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Bosses[edit | edit source]

Boss Blighted Ovum.png
Boss Dingle.png
Boss The Duke of Flies.png
Boss Fistula.png
Blighted Ovum Dingle The Duke of Flies Fistula
Boss Gemini.png
Boss Gurglings.png
Boss The Haunt.png
Boss Larry Jr..png
Gemini Gurglings The Haunt Larry Jr.
Boss Monstro.png Boss Pin.png
Boss Widow.png
Boss Steven.png
Monstro Pin Widow Steven Needs to be unlocked
Boss Famine.png
Boss Carrion Queen.png
Boss Chub.png
Boss Dark One.png
Famine Needs to be unlocked Carrion Queen Chub Dark One
Boss Gurdy.png
Boss The Hollow.png
Boss The Husk.png
Boss Mega Fatty.png
Gurdy The Hollow The Husk Mega Fatty
Boss Gurdy Jr..png
Boss Mega Maw.png
Boss Peep.png
Boss Polycephalus.png
Gurdy Jr. Mega Maw Peep Polycephalus
Boss The Wretched.png
Boss C.H.A.D..png
Boss Pestilence.png
Boss The Adversary.png
The Wretched C.H.A.D. Needs to be unlocked Pestilence Needs to be unlocked The Adversary
Boss The Bloat.png
Boss The Cage.png
Boss The Gate.png
Boss Loki.png
The Bloat The Cage The Gate Loki
Boss Mask Of Infamy.png
Boss Monstro II.png
Boss Gish.png
Boss War.png
Mask of Infamy Monstro II Gish Needs to be unlocked War Needs to be unlocked
Boss Blastocyst.png
Boss Daddy Long Legs.png
Boss Lokii.png
Boss Mama Gurdy.png
Blastocyst Daddy Long Legs Lokii Mama Gurdy
Boss Mr. Fred.png
Boss Scolex.png
Boss Teratoma.png
Boss Triachnid.png
Mr. Fred Scolex Teratoma Triachnid Needs to be unlocked
Boss Death.png
Boss Conquest.png
Boss The Headless Horseman.png
Boss The Fallen.png
Death Needs to be unlocked Conquest Needs to be unlocked The Headless Horseman Needs to be unlocked The Fallen Requires previous entry into a devil room

Afterbirth Added in Afterbirth[edit | edit source]

Boss Dangle.png
Boss Little Horn.png
Boss Rag Man.png
Boss Turdlings.png
Dangle Added in Afterbirth Needs to be unlocked Little Horn Added in Afterbirth Needs to be unlocked Rag Man Added in Afterbirth Needs to be unlocked Turdlings Added in Afterbirth Needs to be unlocked
Boss Brownie.png
Boss The Forsaken.png
Boss The Frail.png
Boss The Stain.png
Brownie Added in Afterbirth Needs to be unlocked The Forsaken Added in Afterbirth Needs to be unlocked The Frail Added in Afterbirth Needs to be unlocked The Stain Added in Afterbirth Needs to be unlocked

Afterbirth+ Added in Afterbirth †[edit | edit source]

Boss Big Horn.png
Boss Rag Mega.png
Boss Sisters Vis.png
Boss The Matriarch.png
Big Horn Added in Afterbirth † Needs to be unlocked Rag Mega Added in Afterbirth † Needs to be unlocked Sisters Vis Added in Afterbirth † Needs to be unlocked The Matriarch Added in Afterbirth † Needs to be unlocked

Repentance Added in Repentance[edit | edit source]

Boss Baby Plum.png
Boss Bumbino.png
Boss Reap Creep.png
Boss The Pile.png
Baby Plum Added in Repentance Bumbino Added in Repentance Reap Creep Added in Repentance The Pile Added in Repentance
Boss Lil Blub (Downpour).png
Boss Wormwood (Downpour).png
Boss The Rainmaker.png
Boss Min-Min.png
Lil Blub (Downpour) Added in Repentance Needs to be unlocked Wormwood (Downpour) Added in Repentance Needs to be unlocked The Rainmaker Added in Repentance Needs to be unlocked Min-Min Added in Repentance Needs to be unlocked
Boss Lil Blub (Dross).png
Boss Wormwood (Dross).png
Boss Clog.png
Boss Colostomia.png
Lil Blub (Dross) Added in Repentance Needs to be unlocked Wormwood (Dross) Added in Repentance Needs to be unlocked Clog Added in Repentance Needs to be unlocked Colostomia Added in Repentance Needs to be unlocked
Boss Turdlet.png
Boss Tuff Twins.png
Boss Hornfel.png
Boss Great Gideon.png
Turdlet Added in Repentance Needs to be unlocked Tuff Twins Added in Repentance Needs to be unlocked Hornfel Added in Repentance Needs to be unlocked Great Gideon Added in Repentance Needs to be unlocked
Boss Singe.png
Boss The Shell.png
Boss The Siren.png
Boss The Heretic.png
Singe Added in Repentance Needs to be unlocked The Shell Added in Repentance Needs to be unlocked The Siren Added in Repentance Needs to be unlocked The Heretic Added in Repentance Needs to be unlocked
Boss The Visage.png
Boss The Horny Boys.png
Boss Rotgut.png
Boss Chimera.png
The Visage Added in Repentance Needs to be unlocked The Horny Boys Added in Repentance Needs to be unlocked Rotgut Added in Repentance Needs to be unlocked Chimera Added in Repentance Needs to be unlocked
Boss The Scourge.png
Ultra Famine.png
Ultra Pestilence.png
Ultra War.png
The Scourge Added in Repentance Needs to be unlocked Ultra Famine Added in Repentance Needs to be unlocked Ultra Pestilence Added in Repentance Needs to be unlocked Ultra War Added in Repentance Needs to be unlocked
Ultra Death.png
Ultra Death Added in Repentance Needs to be unlocked

Final Bosses[edit | edit source]

Boss Mom.png
Boss Mom's Heart.png
Boss It Lives.png
Mom Mom's Heart It Lives Needs to be unlocked
Boss Satan.png
Boss Isaac.png
Boss The Lamb.png
???
Satan Isaac The Lamb ???
Boss Mega Satan.png
Boss Hush.png
Boss Delirium.png
Mega Satan Needs to be unlocked Hush Added in Afterbirth Needs to be unlocked Delirium Added in Afterbirth † Needs to be unlocked
Boss Mother.png
Boss Dogma.png
The Beast ingame.png
Mother Added in Repentance Needs to be unlocked Dogma Added in Repentance Needs to be unlocked The Beast Added in Repentance Needs to be unlocked
Boss Ultra Greed.png
Boss Ultra Greedier.png
Ultra Greed Added in Afterbirth Ultra Greedier Added in Afterbirth † Needs to be unlocked


Bosses Boss Monstro.png
Chapter 1
Stage The Basement icon.pngStage The Cellar icon.pngStage Burning Basement icon.png
GeminiStevenBlighted OvumDingleThe Duke of FliesFamineGurglingsThe HauntLarry Jr.MonstroPinWidowThe FallenThe Headless Horseman
DangleLittle HornRag ManTurdlings
Baby Plum
Chapter 1.5
Stage Downpour icon.pngStage Dross icon.png
Lil BlubWormwoodThe RainmakerMin-MinClogColostomiaTurdlet
Chapter 2
Stage The Caves icon.pngStage The Catacombs icon.pngStage Flooded Caves icon.png
FistulaChubC.H.A.D.Carrion QueenDark OneGurdyGurdy Jr.The HollowThe HuskMega FattyMega MawPeepPestilencePolycephalusThe WretchedThe FallenThe Headless Horseman
The ForsakenThe FrailThe Stain
Big HornRag Mega
Bumbino
Chapter 2.5
Stage Mines icon.pngStage Ashpit icon.png
Reap CreepTuff TwinsHornfelGreat GideonSingeThe ShellThe Pile
Chapter 3
Stage The Depths icon.pngStage Necropolis icon.pngStage Dank Depths icon.png
The AdversaryThe BloatThe CageThe GateMonstro IIGishLokiMask of InfamyWarThe FallenThe Headless HorsemanMom
Brownie
Sisters Vis
Reap CreepThe Pile
Chapter 3.5
Stage Mausoleum icon.pngStage Gehenna icon.png
The SirenThe HereticThe VisageThe Horny BoysMomMom's Heart
Chapter 4
Stage The Womb icon.pngStage Utero icon.pngStage Scarred Womb icon.png
BlastocystThe BloatConquestDaddy Long LegsTriachnidDeathLokiiMama GurdyMr. FredScolexTeratomaThe FallenThe Headless HorsemanMom's HeartIt Lives
Sisters VisThe Matriarch
???
???
Hush
Corpse
Stage Corpse icon.png
ChimeraThe ScourgeRotgutMother
Chapter 5
Stage Sheol icon.pngStage Cathedral icon.png
SatanIsaac
Chapter 6
Stage Dark Room icon.pngStage The Chest icon.png
???The LambMega Satan
The Void
Stage The Void icon.png
Delirium
Home
Stage Home icon.png
DogmaThe BeastUltra DeathUltra FamineUltra PestilenceUltra War
Greed Mode
Ultra Greed
Ultra Greed
Ultra Greedier
The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth
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Characters Characters MainPageBabies.png Co-op Items Items Item pools Item pools Monsters Monsters Objects Objects
Pickups Pickups Pills Pills Rooms Rooms Seeds Seeds Transformations Transformations Trinkets Trinkets