Adrenaline

"Panic = power"
Entity ID	5.100.493
Item Pool	Devil Beggar Treasure Room Treasure Room
Collection Grid	(page 5, column 8, row 1) (page 5, column 9, row 1)

Adrenaline is a passive item added in The Binding of Isaac: Afterbirth †.

Effects

• Gives Isaac a flat damage up based on how many empty Heart containers he has.
  • The damage up given is 0.2 for each empty Red Heart container Isaac has.
  • Damage ups are only applied for every fully empty heart container.
  • The damage up given is ((2 * MissingHearts) ^ 1.6) * 0.1, where MissingHearts is the total half red hearts of health missing.
• This item belongs to the Spun set. Collecting three items from this set will transform Isaac into a buff berserker.

Notes

• This item has no effect on characters that can't have any Red Heart containers.
• This item affects both Keeper and Tainted Keeper; empty Coin Hearts increase damage.
• As The Forgotten, empty Bone Hearts increase damage, but if the Bone Hearts are broken, the damage buff is taken away.

Trivia

• Before v1.06.0190, Adrenaline was named Adderline.
  • Despite having its name changed, Adrenaline's item sprite is named collectibles_493_adderline in the game files.
• Adrenaline is a hormone produced by the body in situations of high stress that increases blood circulation, breathing, and other things in preparation for the natural flight or fight reflex.
• Adrenaline causes characters to have an animation that makes them look like they are breathing rapidly. The more health they're missing, the more exaggerated the animation is.

Syringes

Items:

• Adrenaline
• Euthanasia
• Experimental Treatment
• Growth Hormones
• Roid Rage
• Speed Ball
• Synthoil
• The Virus

Trinkets:

• Broken Syringe