Adrenaline

Item Icon
Pickup Quote	"Panic = power"
Entity ID	5.100.493
Item Pool	Devil Beggar Treasure Room Treasure Room
Quality	1
Item Tags
Collection Grid	(page 5, column 8, row 1) (page 5, column 9, row 1)

Adrenaline is a passive item added in The Binding of Isaac: Afterbirth †.

Effects

• Gives Isaac a flat damage up based on how many empty Heart containers he has.
  • The damage up given is 0.2 for each empty Red Heart container Isaac has.
  • Damage ups are only applied for every fully empty heart container.
  • The damage up given is ((2 * MissingHearts) ^ 1.6) * 0.1, where MissingHearts is the number of full red hearts of health missing.
• This item belongs to the Spun set. Collecting three items from this set will transform Isaac into a buff berserker.

Notes

• This item has no effect on characters that can't have any Red Heart containers.
• This item affects both Keeper and Tainted Keeper; empty Coin Hearts increase damage.
• As The Forgotten, empty Bone Hearts increase damage, but if the Bone Hearts are broken, the damage buff is taken away.

Synergies

• Blood Oath: Activates the damage up effect of Adrenaline for the resulting empty heart containers at the start of each floor.

Trivia

• Before v1.06.0190, Adrenaline was named Adderline.
  • Despite having its name changed, Adrenaline's item sprite is named collectibles_493_adderline in the game files.
• Adrenaline is a hormone produced by the body in situations of high stress that increases blood circulation, breathing, and other things in preparation for the natural flight or fight reflex.
• Adrenaline causes characters to have an animation that makes them look like they are breathing rapidly. The more health they're missing, the more exaggerated the animation is.

The Binding of Isaac: Rebirth
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