A Card Against Humanity

Special Cards

Rebirth	Suicide King	Chaos Card	Credit Card	Rules Card	A Card Against Humanity
Afterbirth	? Card	Get out of Jail Free Card	Emergency Contact	Dice Shard
Afterbirth †	Holy Card	Huge Growth	Ancient Recall	Era Walk

     

"Something stinks..."

Pickup ID
5.300.45

Type:  Special card

Unlock Method
Complete When Life Gives You Lemons (challenge #12)

A Card Against Humanity is a special card.

Effect

• Fills the entire room with Poop.

Notes

• Poop will not fill tiles with obstacles, even if they have already been destroyed.
• The process is not instant and the room will not get filled if Isaac leaves before it's done filling.
• It is more beneficial to use the card in a large-sized room as it will create more Poop piles.
• Using A Card Against Humanity in the Ultra Greedier fight will result in Golden Poops spawning after defeating the boss.
• Using A Card Against Humanity in the Ultra Greed fight can trap the Gapers after Key Coins appear, preventing Ultra Greed from attacking.

Synergies

• Hallowed Ground: Spawned Poops have a high chance to turn into White Poop.
• Infested! pill: Every pile of Poop spawns a Blue Spider.
• Leo/ The Nail/ Thunder Thighs: Allows all the Poop to be easily destroyed.
• Lil Larva: Every pile of Poop spawns a Blue Fly.
• Midas' Touch: Spawned Poops have a great chance to turn into Golden Poops.
• Petrified Poop: Greatly increases the chance of finding a pickup when destroying Poop.

Interactions

• Brown Cap: All the Poop explodes in a chain reaction once one is destroyed.
• Dr. Fetus/ Ipecac: If Isaac has no other means of destroying Poop than his explosive tears, he will have to hurt himself to clear out a path through the Poop unless he has acquired Pyromaniac or Host Hat.

Trivia

• The item is a reference to Cards Against Humanity, a satirical card game whose name in turn references "crimes against humanity". Specifically, it refers to the way the first player is chosen: Whoever was the last to poop goes first.
• In the pop-up (if not disabled) for unlocking this card, the text on it reads "A room full of poop".
  • This actually contradicts the original card game, as black cards are prompts while the white cards are answers to the prompt.

Poop

Items:

• Butt Bombs
• Dirty Mind
• E Coli
• Flush!
• Hallowed Ground
• IBS
• Montezuma's Revenge
• No. 2
• The Poop
• Skatole

Trinkets:

• Brown Cap
• Dingle Berry
• Meconium
• Mysterious Candy
• Petrified Poop
• Used Diaper

Cards:

• A Card Against Humanity