A Card Against Humanity

A Card Against Humanity is a special card.

Effect[]

Poop will not fill tiles with obstacles, even if they have already been destroyed.
The process is not instant and the room will not get fully filled if Isaac leaves before it's done filling.
It is more beneficial to use the card in a large-sized room as it will create more poop piles.
Using A Card Against Humanity in the Ultra Greedier fight will result in Golden Poops spawning after defeating the boss.
- Results in Yellow Poops which only have normal drops.
Using A Card Against Humanity in the Ultra Greed fight can trap the Gapers after Key Coins appear, preventing Ultra Greed from attacking.

Hallowed Ground: Spawned Poops have a high chance to turn into White Poop.
Infested! pill: Every pile of Poop spawns a Blue Spider.
Lil Larva: Every pile of poop spawns a Blue Fly.
Midas' Touch: Spawned poops have a great chance to turn into Golden Poops.
Petrified Poop: Greatly increases the chance of finding a pickup when destroying poop. It's extremely likely to be obtained when using the card in larger, less obstructed rooms.

Brown Cap: All the Poop explodes in a chain reaction once one is destroyed.
Dr. Fetus/ Ipecac: If Isaac has no other means of destroying Poop than his explosive tears, he will have to hurt himself to clear out a path through the Poop unless he has acquired Pyromaniac or Host Hat.
Home: If used in the living room, the poop will cause the couch and TV to move erratically.

The item is a reference to Cards Against Humanity, a satirical card game whose name in turn references "crimes against humanity". Specifically, it refers to the way the first player is chosen: Whoever was the last to poop goes first.
In the pop-up (if not disabled) for unlocking this card, the text on it reads "A room full of poop".
- This actually contradicts the original card game, as black cards are prompts while the white cards are answers to the prompt.

Poop

Items: