- Applies fear to enemies in a small radius around Isaac.
- 2Spooky can be used to manipulate Ultra Greed. Once Greed Gapers spawn and Ultra Greed in his resistance stance, the gapers will be feared when getting close, leaving the boss unable to move or damage Isaac.
- Venus: Overrides 2Spooky.
- The name is a nod to the "2spooky4me" meme. Isaac's appearance also makes him appear similar to popular internet horror images, such as Squidward's Suicide and Giygas from Earthbound.
|The Binding of Isaac: Rebirth|
|Achievements||Attributes||Bosses||Cards and Runes||Challenges||Chapters|